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327 related items for PubMed ID: 10861059

  • 1. TCR/CD3-Induced activation and binding of Emt/Itk to linker of activated T cell complexes: requirement for the Src homology 2 domain.
    Ching KA, Grasis JA, Tailor P, Kawakami Y, Kawakami T, Tsoukas CD.
    J Immunol; 2000 Jul 01; 165(1):256-62. PubMed ID: 10861059
    [Abstract] [Full Text] [Related]

  • 2. Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment.
    Shan X, Wange RL.
    J Biol Chem; 1999 Oct 08; 274(41):29323-30. PubMed ID: 10506192
    [Abstract] [Full Text] [Related]

  • 3. Control of TCR-mediated activation of beta 1 integrins by the ZAP-70 tyrosine kinase interdomain B region and the linker for activation of T cells adapter protein.
    Goda S, Quale AC, Woods ML, Felthauser A, Shimizu Y.
    J Immunol; 2004 May 01; 172(9):5379-87. PubMed ID: 15100278
    [Abstract] [Full Text] [Related]

  • 4. Inducible T cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the T cell antigen receptor.
    Grasis JA, Browne CD, Tsoukas CD.
    J Immunol; 2003 Apr 15; 170(8):3971-6. PubMed ID: 12682224
    [Abstract] [Full Text] [Related]

  • 5. Phosphorylation of the linker for activation of T-cells by Itk promotes recruitment of Vav.
    Perez-Villar JJ, Whitney GS, Sitnick MT, Dunn RJ, Venkatesan S, O'Day K, Schieven GL, Lin TA, Kanner SB.
    Biochemistry; 2002 Aug 27; 41(34):10732-40. PubMed ID: 12186560
    [Abstract] [Full Text] [Related]

  • 6. Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes.
    Perez-Villar JJ, Kanner SB.
    J Immunol; 1999 Dec 15; 163(12):6435-41. PubMed ID: 10586033
    [Abstract] [Full Text] [Related]

  • 7. T cell-specific adapter protein inhibits T cell activation by modulating Lck activity.
    Sundvold V, Torgersen KM, Post NH, Marti F, King PD, Røttingen JA, Spurkland A, Lea T.
    J Immunol; 2000 Sep 15; 165(6):2927-31. PubMed ID: 10975797
    [Abstract] [Full Text] [Related]

  • 8. Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade.
    Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ.
    J Biol Chem; 2000 Jan 21; 275(3):2219-30. PubMed ID: 10636929
    [Abstract] [Full Text] [Related]

  • 9. Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine.
    Kremer KN, Humphreys TD, Kumar A, Qian NX, Hedin KE.
    J Immunol; 2003 Jul 01; 171(1):360-7. PubMed ID: 12817019
    [Abstract] [Full Text] [Related]

  • 10. The adaptor protein Gads (Grb2-related adaptor downstream of Shc) is implicated in coupling hemopoietic progenitor kinase-1 to the activated TCR.
    Liu SK, Smith CA, Arnold R, Kiefer F, McGlade CJ.
    J Immunol; 2000 Aug 01; 165(3):1417-26. PubMed ID: 10903746
    [Abstract] [Full Text] [Related]

  • 11. Regulation of beta 1 integrin-mediated adhesion by T cell receptor signaling involves ZAP-70 but differs from signaling events that regulate transcriptional activity.
    Epler JA, Liu R, Chung H, Ottoson NC, Shimizu Y.
    J Immunol; 2000 Nov 01; 165(9):4941-9. PubMed ID: 11046020
    [Abstract] [Full Text] [Related]

  • 12. Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain.
    Yang WC, Ching KA, Tsoukas CD, Berg LJ.
    J Immunol; 2001 Jan 01; 166(1):387-95. PubMed ID: 11123316
    [Abstract] [Full Text] [Related]

  • 13. Phosphatidylinositol 3-kinase is required for CD28 but not CD3 regulation of the TEC family tyrosine kinase EMT/ITK/TSK: functional and physical interaction of EMT with phosphatidylinositol 3-kinase.
    Lu Y, Cuevas B, Gibson S, Khan H, LaPushin R, Imboden J, Mills GB.
    J Immunol; 1998 Nov 15; 161(10):5404-12. PubMed ID: 9820515
    [Abstract] [Full Text] [Related]

  • 14. Emt/Itk associates with activated TCR complexes: role of the pleckstrin homology domain.
    Ching KA, Kawakami Y, Kawakami T, Tsoukas CD.
    J Immunol; 1999 Dec 01; 163(11):6006-13. PubMed ID: 10570288
    [Abstract] [Full Text] [Related]

  • 15. Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells.
    Paz PE, Wang S, Clarke H, Lu X, Stokoe D, Abo A.
    Biochem J; 2001 Jun 01; 356(Pt 2):461-71. PubMed ID: 11368773
    [Abstract] [Full Text] [Related]

  • 16. Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line.
    Zhang W, Irvin BJ, Trible RP, Abraham RT, Samelson LE.
    Int Immunol; 1999 Jun 01; 11(6):943-50. PubMed ID: 10360968
    [Abstract] [Full Text] [Related]

  • 17. Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.
    Zhu M, Janssen E, Zhang W.
    J Immunol; 2003 Jan 01; 170(1):325-33. PubMed ID: 12496416
    [Abstract] [Full Text] [Related]

  • 18. The role of Tec protein-tyrosine kinase in T cell signaling.
    Yang WC, Ghiotto M, Barbarat B, Olive D.
    J Biol Chem; 1999 Jan 08; 274(2):607-17. PubMed ID: 9872994
    [Abstract] [Full Text] [Related]

  • 19. Itk, a T cell-specific tyrosine kinase, is required for CD2-mediated interleukin-2 promoter activation in the human T cell line Jurkat.
    Tanaka N, Abe H, Yagita H, Okumura K, Nakamura M, Sugamura K.
    Eur J Immunol; 1997 Apr 08; 27(4):834-41. PubMed ID: 9130632
    [Abstract] [Full Text] [Related]

  • 20. Itk Promotes the Integration of TCR and CD28 Costimulation through Its Direct Substrates SLP-76 and Gads.
    Hallumi E, Shalah R, Lo WL, Corso J, Oz I, Beach D, Wittman S, Isenberg A, Sela M, Urlaub H, Weiss A, Yablonski D.
    J Immunol; 2021 May 15; 206(10):2322-2337. PubMed ID: 33931484
    [Abstract] [Full Text] [Related]

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