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351 related items for PubMed ID: 10861294

  • 1. DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis.
    Strissel PL, Strick R, Tomek RJ, Roe BA, Rowley JD, Zeleznik-Le NJ.
    Hum Mol Genet; 2000 Jul 01; 9(11):1671-9. PubMed ID: 10861294
    [Abstract] [Full Text] [Related]

  • 2. An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region.
    Strissel PL, Strick R, Rowley JD, Zeleznik-Le NJ.
    Blood; 1998 Nov 15; 92(10):3793-803. PubMed ID: 9808573
    [Abstract] [Full Text] [Related]

  • 3. Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.
    Langer T, Metzler M, Reinhardt D, Viehmann S, Borkhardt A, Reichel M, Stanulla M, Schrappe M, Creutzig U, Ritter J, Leis T, Jacobs U, Harbott J, Beck JD, Rascher W, Repp R.
    Genes Chromosomes Cancer; 2003 Apr 15; 36(4):393-401. PubMed ID: 12619163
    [Abstract] [Full Text] [Related]

  • 4. Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia.
    Super HG, Strissel PL, Sobulo OM, Burian D, Reshmi SC, Roe B, Zeleznik-Le NJ, Diaz MO, Rowley JD.
    Genes Chromosomes Cancer; 1997 Oct 15; 20(2):185-95. PubMed ID: 9331569
    [Abstract] [Full Text] [Related]

  • 5. Chromatin structural elements and chromosomal translocations in leukemia.
    Zhang Y, Rowley JD.
    DNA Repair (Amst); 2006 Sep 08; 5(9-10):1282-97. PubMed ID: 16893685
    [Abstract] [Full Text] [Related]

  • 6. Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
    Broeker PL, Super HG, Thirman MJ, Pomykala H, Yonebayashi Y, Tanabe S, Zeleznik-Le N, Rowley JD.
    Blood; 1996 Mar 01; 87(5):1912-22. PubMed ID: 8634439
    [Abstract] [Full Text] [Related]

  • 7. Common chromatin structures at breakpoint cluster regions may lead to chromosomal translocations found in chronic and acute leukemias.
    Strick R, Zhang Y, Emmanuel N, Strissel PL.
    Hum Genet; 2006 Jun 01; 119(5):479-95. PubMed ID: 16572268
    [Abstract] [Full Text] [Related]

  • 8. Characterization of genomic breakpoints in MLL and CBP in leukemia patients with t(11;16).
    Zhang Y, Zeleznik-Le N, Emmanuel N, Jayathilaka N, Chen J, Strissel P, Strick R, Li L, Neilly MB, Taki T, Hayashi Y, Kaneko Y, Schlegelberger B, Rowley JD.
    Genes Chromosomes Cancer; 2004 Nov 01; 41(3):257-65. PubMed ID: 15334549
    [Abstract] [Full Text] [Related]

  • 9. A novel chromosomal inversion at 11q23 in infant acute myeloid leukemia fuses MLL to CALM, a gene that encodes a clathrin assembly protein.
    Wechsler DS, Engstrom LD, Alexander BM, Motto DG, Roulston D.
    Genes Chromosomes Cancer; 2003 Jan 01; 36(1):26-36. PubMed ID: 12461747
    [Abstract] [Full Text] [Related]

  • 10. MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site.
    Slater DJ, Hilgenfeld E, Rappaport EF, Shah N, Meek RG, Williams WR, Lovett BD, Osheroff N, Autar RS, Ried T, Felix CA.
    Oncogene; 2002 Jul 11; 21(30):4706-14. PubMed ID: 12096348
    [Abstract] [Full Text] [Related]

  • 11. All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders.
    Rowley JD, Reshmi S, Sobulo O, Musvee T, Anastasi J, Raimondi S, Schneider NR, Barredo JC, Cantu ES, Schlegelberger B, Behm F, Doggett NA, Borrow J, Zeleznik-Le N.
    Blood; 1997 Jul 15; 90(2):535-41. PubMed ID: 9226152
    [Abstract] [Full Text] [Related]

  • 12. Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.
    Zhang Y, Strissel P, Strick R, Chen J, Nucifora G, Le Beau MM, Larson RA, Rowley JD.
    Proc Natl Acad Sci U S A; 2002 Mar 05; 99(5):3070-5. PubMed ID: 11867721
    [Abstract] [Full Text] [Related]

  • 13. Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia.
    Strick R, Strissel PL, Borgers S, Smith SL, Rowley JD.
    Proc Natl Acad Sci U S A; 2000 Apr 25; 97(9):4790-5. PubMed ID: 10758153
    [Abstract] [Full Text] [Related]

  • 14. Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.
    Whitmarsh RJ, Saginario C, Zhuo Y, Hilgenfeld E, Rappaport EF, Megonigal MD, Carroll M, Liu M, Osheroff N, Cheung NK, Slater DJ, Ried T, Knutsen T, Blair IA, Felix CA.
    Oncogene; 2003 Nov 20; 22(52):8448-59. PubMed ID: 14627986
    [Abstract] [Full Text] [Related]

  • 15. Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).
    Domer PH, Head DR, Renganathan N, Raimondi SC, Yang E, Atlas M.
    Leukemia; 1995 Aug 20; 9(8):1305-12. PubMed ID: 7643617
    [Abstract] [Full Text] [Related]

  • 16. MLL genomic breakpoint distribution within the breakpoint cluster region in de novo leukemia in children.
    Felix CA, Hosler MR, Slater DJ, Parker RI, Masterson M, Whitlock JA, Rebbeck TR, Nowell PC, Lange BJ.
    J Pediatr Hematol Oncol; 1998 Aug 20; 20(4):299-308. PubMed ID: 9703001
    [Abstract] [Full Text] [Related]

  • 17. Apoptotic stimuli initiate MLL-AF9 translocations that are transcribed in cells capable of division.
    Betti CJ, Villalobos MJ, Diaz MO, Vaughan AT.
    Cancer Res; 2003 Mar 15; 63(6):1377-81. PubMed ID: 12649202
    [Abstract] [Full Text] [Related]

  • 18. Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with an MLL-AF9 translocation.
    Odero MD, Zeleznik-Le NJ, Chinwalla V, Rowley JD.
    Genes Chromosomes Cancer; 2000 Dec 15; 29(4):333-8. PubMed ID: 11066077
    [Abstract] [Full Text] [Related]

  • 19. Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.
    Lovett BD, Lo Nigro L, Rappaport EF, Blair IA, Osheroff N, Zheng N, Megonigal MD, Williams WR, Nowell PC, Felix CA.
    Proc Natl Acad Sci U S A; 2001 Aug 14; 98(17):9802-7. PubMed ID: 11493704
    [Abstract] [Full Text] [Related]

  • 20. Identification of a novel RAS GTPase-activating protein (RASGAP) gene at 9q34 as an MLL fusion partner in a patient with de novo acute myeloid leukemia.
    von Bergh AR, Wijers PM, Groot AJ, van Zelderen-Bhola S, Falkenburg JH, Kluin PM, Schuuring E.
    Genes Chromosomes Cancer; 2004 Apr 14; 39(4):324-34. PubMed ID: 14978793
    [Abstract] [Full Text] [Related]

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