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364 related items for PubMed ID: 10861295

  • 1. DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways.
    Fuentes JJ, Genescà L, Kingsbury TJ, Cunningham KW, Pérez-Riba M, Estivill X, de la Luna S.
    Hum Mol Genet; 2000 Jul 01; 9(11):1681-90. PubMed ID: 10861295
    [Abstract] [Full Text] [Related]

  • 2. A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2).
    Strippoli P, Lenzi L, Petrini M, Carinci P, Zannotti M.
    Genomics; 2000 Mar 15; 64(3):252-63. PubMed ID: 10756093
    [Abstract] [Full Text] [Related]

  • 3. Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathway.
    Cano E, Canellada A, Minami T, Iglesias T, Redondo JM.
    J Biol Chem; 2005 Aug 19; 280(33):29435-43. PubMed ID: 15975916
    [Abstract] [Full Text] [Related]

  • 4. VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis?
    Yao YG, Duh EJ.
    Biochem Biophys Res Commun; 2004 Aug 27; 321(3):648-56. PubMed ID: 15358155
    [Abstract] [Full Text] [Related]

  • 5. DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice.
    Lange AW, Molkentin JD, Yutzey KE.
    Dev Biol; 2004 Feb 15; 266(2):346-60. PubMed ID: 14738882
    [Abstract] [Full Text] [Related]

  • 6. A calcineurin inhibitory protein overexpressed in Down's syndrome interacts with the product of a ubiquitously expressed transcript.
    Silveira HC, Sommer CA, Soares-Costa A, Henrique-Silva F.
    Braz J Med Biol Res; 2004 Jun 15; 37(6):785-9. PubMed ID: 15264020
    [Abstract] [Full Text] [Related]

  • 7. Restoration of DSCR1 to disomy in the trisomy 16 mouse model of Down syndrome does not correct cardiac or craniofacial development anomalies.
    Lange AW, Rothermel BA, Yutzey KE.
    Dev Dyn; 2005 Jul 15; 233(3):954-63. PubMed ID: 15906378
    [Abstract] [Full Text] [Related]

  • 8. A conserved family of calcineurin regulators.
    Kingsbury TJ, Cunningham KW.
    Genes Dev; 2000 Jul 01; 14(13):1595-604. PubMed ID: 10887154
    [Abstract] [Full Text] [Related]

  • 9. Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development.
    Wu H, Kao SC, Barrientos T, Baldwin SH, Olson EN, Crabtree GR, Zhou B, Chang CP.
    J Biol Chem; 2007 Oct 19; 282(42):30673-9. PubMed ID: 17693409
    [Abstract] [Full Text] [Related]

  • 10. Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway.
    Qin L, Zhao D, Liu X, Nagy JA, Hoang MV, Brown LF, Dvorak HF, Zeng H.
    Mol Cancer Res; 2006 Nov 19; 4(11):811-20. PubMed ID: 17114339
    [Abstract] [Full Text] [Related]

  • 11. A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.
    Rothermel B, Vega RB, Yang J, Wu H, Bassel-Duby R, Williams RS.
    J Biol Chem; 2000 Mar 24; 275(12):8719-25. PubMed ID: 10722714
    [Abstract] [Full Text] [Related]

  • 12. Down syndrome candidate region 1-like 1 (DSCR1-L1) mimics the inhibitory effects of DSCR1 on calcineurin signaling in endothelial cells and inhibits angiogenesis.
    Gollogly LK, Ryeom SW, Yoon SS.
    J Surg Res; 2007 Sep 24; 142(1):129-36. PubMed ID: 17610901
    [Abstract] [Full Text] [Related]

  • 13. Mutational analyses of the signals involved in the subcellular location of DSCR1.
    Pfister SC, Machado-Santelli GM, Han SW, Henrique-Silva F.
    BMC Cell Biol; 2002 Sep 11; 3():24. PubMed ID: 12225619
    [Abstract] [Full Text] [Related]

  • 14. The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes.
    Strippoli P, Petrini M, Lenzi L, Carinci P, Zannotti M.
    Gene; 2000 Oct 31; 257(2):223-32. PubMed ID: 11080588
    [Abstract] [Full Text] [Related]

  • 15. Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells.
    Hesser BA, Liang XH, Camenisch G, Yang S, Lewin DA, Scheller R, Ferrara N, Gerber HP.
    Blood; 2004 Jul 01; 104(1):149-58. PubMed ID: 15016650
    [Abstract] [Full Text] [Related]

  • 16. A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart.
    Fuentes JJ, Pritchard MA, Planas AM, Bosch A, Ferrer I, Estivill X.
    Hum Mol Genet; 1995 Oct 01; 4(10):1935-44. PubMed ID: 8595418
    [Abstract] [Full Text] [Related]

  • 17. Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo.
    Chan B, Greenan G, McKeon F, Ellenberger T.
    Proc Natl Acad Sci U S A; 2005 Sep 13; 102(37):13075-80. PubMed ID: 16131541
    [Abstract] [Full Text] [Related]

  • 18. Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.
    Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Folkman J, Daley GQ, Aird WC, Galdzicki Z, Ryeom S.
    Nature; 2009 Jun 25; 459(7250):1126-30. PubMed ID: 19458618
    [Abstract] [Full Text] [Related]

  • 19. Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3β signaling.
    Shaw JL, Chang KT.
    PLoS Genet; 2013 Jun 25; 9(9):e1003792. PubMed ID: 24086147
    [Abstract] [Full Text] [Related]

  • 20. Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease.
    Ermak G, Morgan TE, Davies KJ.
    J Biol Chem; 2001 Oct 19; 276(42):38787-94. PubMed ID: 11483593
    [Abstract] [Full Text] [Related]

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