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189 related items for PubMed ID: 10873856

  • 1. A new allosteric site in glycogen phosphorylase b as a target for drug interactions.
    Oikonomakos NG, Skamnaki VT, Tsitsanou KE, Gavalas NG, Johnson LN.
    Structure; 2000 Jun 15; 8(6):575-84. PubMed ID: 10873856
    [Abstract] [Full Text] [Related]

  • 2. Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
    Barford D, Hu SH, Johnson LN.
    J Mol Biol; 1991 Mar 05; 218(1):233-60. PubMed ID: 1900534
    [Abstract] [Full Text] [Related]

  • 3. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate.
    Oikonomakos NG, Tsitsanou KE, Zographos SE, Skamnaki VT, Goldmann S, Bischoff H.
    Protein Sci; 1999 Oct 05; 8(10):1930-45. PubMed ID: 10548038
    [Abstract] [Full Text] [Related]

  • 4. The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor.
    Zographos SE, Oikonomakos NG, Tsitsanou KE, Leonidas DD, Chrysina ED, Skamnaki VT, Bischoff H, Goldmann S, Watson KA, Johnson LN.
    Structure; 1997 Nov 15; 5(11):1413-25. PubMed ID: 9384557
    [Abstract] [Full Text] [Related]

  • 5. The 1.76 A resolution crystal structure of glycogen phosphorylase B complexed with glucose, and CP320626, a potential antidiabetic drug.
    Oikonomakos NG, Zographos SE, Skamnaki VT, Archontis G.
    Bioorg Med Chem; 2002 May 15; 10(5):1313-9. PubMed ID: 11886794
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution.
    Oikonomakos NG, Chrysina ED, Kosmopoulou MN, Leonidas DD.
    Biochim Biophys Acta; 2003 Apr 11; 1647(1-2):325-32. PubMed ID: 12686153
    [Abstract] [Full Text] [Related]

  • 7. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol.
    Tsitsanou KE, Hayes JM, Keramioti M, Mamais M, Oikonomakos NG, Kato A, Leonidas DD, Zographos SE.
    Food Chem Toxicol; 2013 Nov 11; 61():14-27. PubMed ID: 23279842
    [Abstract] [Full Text] [Related]

  • 8. Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.
    Chrysina ED, Kosmopoulou MN, Tiraidis C, Kardakaris R, Bischler N, Leonidas DD, Hadady Z, Somsak L, Docsa T, Gergely P, Oikonomakos NG.
    Protein Sci; 2005 Apr 11; 14(4):873-88. PubMed ID: 15741340
    [Abstract] [Full Text] [Related]

  • 9. 1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
    Tsirkone VG, Tsoukala E, Lamprakis C, Manta S, Hayes JM, Skamnaki VT, Drakou C, Zographos SE, Komiotis D, Leonidas DD.
    Bioorg Med Chem; 2010 May 15; 18(10):3413-25. PubMed ID: 20430629
    [Abstract] [Full Text] [Related]

  • 10. Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate.
    Leonidas DD, Oikonomakos NG, Papageorgiou AC, Acharya KR, Barford D, Johnson LN.
    Protein Sci; 1992 Sep 15; 1(9):1112-22. PubMed ID: 1304390
    [Abstract] [Full Text] [Related]

  • 11. Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase B.
    Oikonomakos NG, Skamnaki VT, Osz E, Szilágyi L, Somsák L, Docsa T, Tóth B, Gergely P.
    Bioorg Med Chem; 2002 Feb 15; 10(2):261-8. PubMed ID: 11741774
    [Abstract] [Full Text] [Related]

  • 12. Physiological control of liver glycogen metabolism: lessons from novel glycogen phosphorylase inhibitors.
    Agius L.
    Mini Rev Med Chem; 2010 Oct 15; 10(12):1175-87. PubMed ID: 20716056
    [Abstract] [Full Text] [Related]

  • 13. Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex.
    Kosmopoulou MN, Leonidas DD, Chrysina ED, Bischler N, Eisenbrand G, Sakarellos CE, Pauptit R, Oikonomakos NG.
    Eur J Biochem; 2004 Jun 15; 271(11):2280-90. PubMed ID: 15153119
    [Abstract] [Full Text] [Related]

  • 14. Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors.
    Gregus Z, Németi B.
    Toxicol Sci; 2007 Nov 15; 100(1):44-53. PubMed ID: 17693424
    [Abstract] [Full Text] [Related]

  • 15. Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.
    Oikonomakos NG, Kosmopoulou MN, Chrysina ED, Leonidas DD, Kostas ID, Wendt KU, Klabunde T, Defossa E.
    Protein Sci; 2005 Jul 15; 14(7):1760-71. PubMed ID: 15987904
    [Abstract] [Full Text] [Related]

  • 16. Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase b.
    Johnson LN, Snape P, Martin JL, Acharya KR, Barford D, Oikonomakos NG.
    J Mol Biol; 1993 Jul 05; 232(1):253-67. PubMed ID: 8331662
    [Abstract] [Full Text] [Related]

  • 17. FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase.
    Tiraidis C, Alexacou KM, Zographos SE, Leonidas DD, Gimisis T, Oikonomakos NG.
    Protein Sci; 2007 Aug 05; 16(8):1773-82. PubMed ID: 17600143
    [Abstract] [Full Text] [Related]

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