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Journal Abstract Search


223 related items for PubMed ID: 10878015

  • 1. GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase.
    Annerén C, Reedquist KA, Bos JL, Welsh M.
    J Biol Chem; 2000 Sep 15; 275(37):29153-61. PubMed ID: 10878015
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  • 2. NGF-Dependent neurite outgrowth in PC12 cells overexpressing the Src homology 2-domain protein shb requires activation of the Rap1 pathway.
    Lu L, Annerén C, Reedquist KA, Bos JL, Welsh M.
    Exp Cell Res; 2000 Sep 15; 259(2):370-7. PubMed ID: 10964504
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  • 3. The FRK/RAK-SHB signaling cascade: a versatile signal-transduction pathway that regulates cell survival, differentiation and proliferation.
    Annerén C, Lindholm CK, Kriz V, Welsh M.
    Curr Mol Med; 2003 Jun 15; 3(4):313-24. PubMed ID: 12776987
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  • 4. The Src homology 2 domain protein Shb transmits basic fibroblast growth factor- and nerve growth factor-dependent differentiation signals in PC12 cells.
    Karlsson T, Kullander K, Welsh M.
    Cell Growth Differ; 1998 Sep 15; 9(9):757-66. PubMed ID: 9751119
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  • 5. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C, Welsh M.
    Mol Med; 2002 Nov 15; 8(11):705-13. PubMed ID: 12520087
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  • 6. Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK.
    Barberis L, Wary KK, Fiucci G, Liu F, Hirsch E, Brancaccio M, Altruda F, Tarone G, Giancotti FG.
    J Biol Chem; 2000 Nov 24; 275(47):36532-40. PubMed ID: 10976102
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  • 7. Characterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation.
    Park SY, Avraham H, Avraham S.
    J Biol Chem; 2000 Jun 30; 275(26):19768-77. PubMed ID: 10764815
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  • 9. The 38-amino-acid form of pituitary adenylate cyclase-activating polypeptide induces neurite outgrowth in PC12 cells that is dependent on protein kinase C and extracellular signal-regulated kinase but not on protein kinase A, nerve growth factor receptor tyrosine kinase, p21(ras) G protein, and pp60(c-src) cytoplasmic tyrosine kinase.
    Lazarovici P, Jiang H, Fink D.
    Mol Pharmacol; 1998 Sep 30; 54(3):547-58. PubMed ID: 9730914
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  • 14. The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth.
    Ashcroft M, Stephens RM, Hallberg B, Downward J, Kaplan DR.
    Oncogene; 1999 Aug 12; 18(32):4586-97. PubMed ID: 10467403
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  • 15. Growth hormone stimulates the formation of a multiprotein signaling complex involving p130(Cas) and CrkII. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK).
    Zhu T, Goh EL, LeRoith D, Lobie PE.
    J Biol Chem; 1998 Dec 11; 273(50):33864-75. PubMed ID: 9837978
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  • 16. Differential utilization of ShcA tyrosine residues and functional domains in the transduction of epidermal growth factor-induced mitogen-activated protein kinase activation in 293T cells and nerve growth factor-induced neurite outgrowth in PC12 cells. Identification of a new Grb2.Sos1 binding site.
    Thomas D, Bradshaw RA.
    J Biol Chem; 1997 Aug 29; 272(35):22293-9. PubMed ID: 9268379
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  • 19. The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells.
    Holmqvist K, Cross M, Riley D, Welsh M.
    Cell Signal; 2003 Feb 29; 15(2):171-9. PubMed ID: 12464388
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  • 20. Nerve growth factor (NGF) induces a rapid and sustained downregulation of the focal adhesion kinase (FAK).
    Gatti A.
    Cell Mol Neurobiol; 2004 Jun 29; 24(3):461-75. PubMed ID: 15206825
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