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Journal Abstract Search

890 related items for PubMed ID: 10878807

  • 1. Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein.
    Ohh M, Park CW, Ivan M, Hoffman MA, Kim TY, Huang LE, Pavletich N, Chau V, Kaelin WG.
    Nat Cell Biol; 2000 Jul; 2(7):423-7. PubMed ID: 10878807
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  • 2. VHL takes HIF's breath away.
    Krek W.
    Nat Cell Biol; 2000 Jul; 2(7):E121-3. PubMed ID: 10878820
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  • 4. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.
    Tanimoto K, Makino Y, Pereira T, Poellinger L.
    EMBO J; 2000 Aug 15; 19(16):4298-309. PubMed ID: 10944113
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  • 6. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
    Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ.
    Science; 2001 Apr 20; 292(5516):468-72. PubMed ID: 11292861
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  • 7. Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.
    Clifford SC, Cockman ME, Smallwood AC, Mole DR, Woodward ER, Maxwell PH, Ratcliffe PJ, Maher ER.
    Hum Mol Genet; 2001 May 01; 10(10):1029-38. PubMed ID: 11331613
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  • 8. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
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  • 9. von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.
    Hoffman MA, Ohh M, Yang H, Klco JM, Ivan M, Kaelin WG.
    Hum Mol Genet; 2001 May 01; 10(10):1019-27. PubMed ID: 11331612
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  • 14. The von Hippel-Lindau tumor suppressor protein.
    Ivan M, Kaelin WG.
    Curr Opin Genet Dev; 2001 Feb 01; 11(1):27-34. PubMed ID: 11163147
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  • 16. Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor.
    Baba M, Hirai S, Yamada-Okabe H, Hamada K, Tabuchi H, Kobayashi K, Kondo K, Yoshida M, Yamashita A, Kishida T, Nakaigawa N, Nagashima Y, Kubota Y, Yao M, Ohno S.
    Oncogene; 2003 May 08; 22(18):2728-38. PubMed ID: 12743597
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  • 17. HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation.
    Yu F, White SB, Zhao Q, Lee FS.
    Proc Natl Acad Sci U S A; 2001 Aug 14; 98(17):9630-5. PubMed ID: 11504942
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  • 20. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.
    Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ.
    EMBO J; 2001 Sep 17; 20(18):5197-206. PubMed ID: 11566883
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