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261 related items for PubMed ID: 10882846

  • 1. Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism.
    Zhang HT, Crissman AM, Dorairaj NR, Chandler LJ, O'Donnell JM.
    Neuropsychopharmacology; 2000 Aug; 23(2):198-204. PubMed ID: 10882846
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus.
    Zhang HT, Zhao Y, Huang Y, Dorairaj NR, Chandler LJ, O'Donnell JM.
    Neuropsychopharmacology; 2004 Aug; 29(8):1432-9. PubMed ID: 15114341
    [Abstract] [Full Text] [Related]

  • 3. Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats.
    Zhang HT, Huang Y, Suvarna NU, Deng C, Crissman AM, Hopper AT, De Vivo M, Rose GM, O'Donnell JM.
    Psychopharmacology (Berl); 2005 May; 179(3):613-9. PubMed ID: 15672274
    [Abstract] [Full Text] [Related]

  • 4. Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
    Suvarna NU, O'Donnell JM.
    J Pharmacol Exp Ther; 2002 Jul; 302(1):249-56. PubMed ID: 12065724
    [Abstract] [Full Text] [Related]

  • 5. Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats.
    Zhang HT, Huang Y, Mishler K, Roerig SC, O'Donnell JM.
    Psychopharmacology (Berl); 2005 Oct; 182(1):104-15. PubMed ID: 16010541
    [Abstract] [Full Text] [Related]

  • 6. Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats.
    Makhay MM, Houslay MD, O'Donnell JM.
    Psychopharmacology (Berl); 2001 Nov; 158(3):297-304. PubMed ID: 11713620
    [Abstract] [Full Text] [Related]

  • 7. Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures.
    Hajjhussein H, Suvarna NU, Gremillion C, Chandler LJ, O'Donnell JM.
    Brain Res; 2007 May 29; 1149():58-68. PubMed ID: 17407767
    [Abstract] [Full Text] [Related]

  • 8. Rolipram attenuates MK-801-induced deficits in latent inhibition.
    Davis JA, Gould TJ.
    Behav Neurosci; 2005 Apr 29; 119(2):595-602. PubMed ID: 15839805
    [Abstract] [Full Text] [Related]

  • 9. Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats.
    Zhang HT, O'Donnell JM.
    Psychopharmacology (Berl); 2000 Jun 29; 150(3):311-6. PubMed ID: 10923759
    [Abstract] [Full Text] [Related]

  • 10. Type 4 cAMP phosphodiesterase (PDE4) inhibitors augment glucocorticoid-mediated apoptosis in B cell chronic lymphocytic leukemia (B-CLL) in the absence of exogenous adenylyl cyclase stimulation.
    Tiwari S, Dong H, Kim EJ, Weintraub L, Epstein PM, Lerner A.
    Biochem Pharmacol; 2005 Feb 01; 69(3):473-83. PubMed ID: 15652238
    [Abstract] [Full Text] [Related]

  • 11. Effects of a phosphodiesterase IV inhibitor rolipram on microsphere embolism-induced defects in memory function and cerebral cyclic AMP signal transduction system in rats.
    Nagakura A, Niimura M, Takeo S.
    Br J Pharmacol; 2002 Apr 01; 135(7):1783-93. PubMed ID: 11934820
    [Abstract] [Full Text] [Related]

  • 12. Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats.
    Rutten K, Van Donkelaar EL, Ferrington L, Blokland A, Bollen E, Steinbusch HW, Kelly PA, Prickaerts JH.
    Neuropsychopharmacology; 2009 Jul 01; 34(8):1914-25. PubMed ID: 19262466
    [Abstract] [Full Text] [Related]

  • 13. The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats.
    Wang C, Yang XM, Zhuo YY, Zhou H, Lin HB, Cheng YF, Xu JP, Zhang HT.
    Int J Neuropsychopharmacol; 2012 Jul 01; 15(6):749-66. PubMed ID: 21733236
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.
    Moon E, Lee R, Near R, Weintraub L, Wolda S, Lerner A.
    Clin Cancer Res; 2002 Feb 01; 8(2):589-95. PubMed ID: 11839681
    [Abstract] [Full Text] [Related]

  • 15. Pregnancy induces a modulation of the cAMP phosphodiesterase 4-conformers ratio in human myometrium: consequences for the utero-relaxant effect of PDE4-selective inhibitors.
    Méhats C, Tanguy G, Paris B, Robert B, Pernin N, Ferré F, Leroy MJ.
    J Pharmacol Exp Ther; 2000 Feb 01; 292(2):817-23. PubMed ID: 10640323
    [Abstract] [Full Text] [Related]

  • 16. Regulation of cyclic AMP in rat pulmonary microvascular endothelial cells by rolipram-sensitive cyclic AMP phosphodiesterase (PDE4).
    Thompson WJ, Ashikaga T, Kelly JJ, Liu L, Zhu B, Vemavarapu L, Strada SJ.
    Biochem Pharmacol; 2002 Feb 15; 63(4):797-807. PubMed ID: 11992650
    [Abstract] [Full Text] [Related]

  • 17. Modulation of rat thymocyte proliferative response through the inhibition of different cyclic nucleotide phosphodiesterase isoforms by means of selective inhibitors and cGMP-elevating agents.
    Marcoz P, Prigent AF, Lagarde M, Nemoz G.
    Mol Pharmacol; 1993 Nov 15; 44(5):1027-35. PubMed ID: 8246905
    [Abstract] [Full Text] [Related]

  • 18. Selective inhibition of phosphodiesterase-4 ameliorates chronic colitis and prevents intestinal fibrosis.
    Videla S, Vilaseca J, Medina C, Mourelle M, Guarner F, Salas A, Malagelada JR.
    J Pharmacol Exp Ther; 2006 Feb 15; 316(2):940-5. PubMed ID: 16254133
    [Abstract] [Full Text] [Related]

  • 19. Rolipram, a phosphodiesterase 4 inhibitor, prevented cancellous and cortical bone loss by inhibiting endosteal bone resorption and maintaining the elevated periosteal bone formation in adult ovariectomized rats.
    Yao W, Tian XY, Chen J, Setterberg RB, Lundy MW, Chmielzwski P, Froman CA, Jee WS.
    J Musculoskelet Neuronal Interact; 2007 Feb 15; 7(2):119-30. PubMed ID: 17627081
    [Abstract] [Full Text] [Related]

  • 20. Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice.
    Wang ZZ, Yang WX, Zhang Y, Zhao N, Zhang YZ, Liu YQ, Xu Y, Wilson SP, O'Donnell JM, Zhang HT, Li YF.
    Sci Rep; 2015 Jul 10; 5():11332. PubMed ID: 26161529
    [Abstract] [Full Text] [Related]

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