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281 related items for PubMed ID: 10905484

  • 1. A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice.
    Fukui Y, Masui S, Osada S, Umesono K, Motojima K.
    Diabetes; 2000 May; 49(5):759-67. PubMed ID: 10905484
    [Abstract] [Full Text] [Related]

  • 2. Peroxisome proliferator-activated receptors gamma and alpha mediate in vivo regulation of uncoupling protein (UCP-1, UCP-2, UCP-3) gene expression.
    Kelly LJ, Vicario PP, Thompson GM, Candelore MR, Doebber TW, Ventre J, Wu MS, Meurer R, Forrest MJ, Conner MW, Cascieri MA, Moller DE.
    Endocrinology; 1998 Dec; 139(12):4920-7. PubMed ID: 9832429
    [Abstract] [Full Text] [Related]

  • 3. Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes.
    Matsuda J, Hosoda K, Itoh H, Son C, Doi K, Hanaoka I, Inoue G, Nishimura H, Yoshimasa Y, Yamori Y, Odaka H, Nakao K.
    Diabetes; 1998 Nov; 47(11):1809-14. PubMed ID: 9792555
    [Abstract] [Full Text] [Related]

  • 4. Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice.
    Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR.
    Endocrinology; 2000 Nov; 141(11):4021-31. PubMed ID: 11089532
    [Abstract] [Full Text] [Related]

  • 5. A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.
    Murakami K, Tobe K, Ide T, Mochizuki T, Ohashi M, Akanuma Y, Yazaki Y, Kadowaki T.
    Diabetes; 1998 Dec; 47(12):1841-7. PubMed ID: 9836514
    [Abstract] [Full Text] [Related]

  • 6. The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat.
    Emilsson V, O'Dowd J, Wang S, Liu YL, Sennitt M, Heyman R, Cawthorne MA.
    Metabolism; 2000 Dec; 49(12):1610-5. PubMed ID: 11145125
    [Abstract] [Full Text] [Related]

  • 7. Effects of growth hormone (GH) on mRNA levels of uncoupling proteins 1, 2, and 3 in brown and white adipose tissues and skeletal muscle in obese mice.
    Hioki C, Yoshida T, Kogure A, Takakura Y, Umekawa T, Yoshioka K, Shimatsu A, Yoshikawa T.
    Horm Metab Res; 2004 Sep; 36(9):607-13. PubMed ID: 15486811
    [Abstract] [Full Text] [Related]

  • 8. Lipoprotein lipase mRNA in white adipose tissue but not in skeletal muscle is increased by pioglitazone through PPAR-gamma.
    Kageyama H, Hirano T, Okada K, Ebara T, Kageyama A, Murakami T, Shioda S, Adachi M.
    Biochem Biophys Res Commun; 2003 May 23; 305(1):22-7. PubMed ID: 12732191
    [Abstract] [Full Text] [Related]

  • 9. Differential effects of YM440 a hypoglycemic agent on binding to a peroxisome proliferator-activated receptor gamma and its transactivation.
    Kurosaki E, Nakano R, Shimaya A, Yoshida S, Ida M, Suzuki T, Shibasaki M, Shikama H.
    Biochem Pharmacol; 2003 Mar 01; 65(5):795-805. PubMed ID: 12628477
    [Abstract] [Full Text] [Related]

  • 10. A novel peroxisome proliferator-activated gamma (PPAR gamma) agonist, CLX-0921, has potent antihyperglycemic activity with low adipogenic potential.
    Dey D, Medicherla S, Neogi P, Gowri M, Cheng J, Gross C, Sharma SD, Reaven GM, Nag B.
    Metabolism; 2003 Aug 01; 52(8):1012-8. PubMed ID: 12898466
    [Abstract] [Full Text] [Related]

  • 11. Thiazolidinediones inhibit the expression of beta3-adrenergic receptors at a transcriptional level.
    Bakopanos E, Silva JE.
    Diabetes; 2000 Dec 01; 49(12):2108-15. PubMed ID: 11118014
    [Abstract] [Full Text] [Related]

  • 12. Effects of pioglitazone on promoting energy storage, not expenditure, in brown adipose tissue of obese fa/fa Zucker rats: comparison to CL 316,243.
    Burkey BF, Dong M, Gagen K, Eckhardt M, Dragonas N, Chen W, Grosenstein P, Argentieri G, de Souza CJ.
    Metabolism; 2000 Oct 01; 49(10):1301-8. PubMed ID: 11079820
    [Abstract] [Full Text] [Related]

  • 13. A novel method for analysis of nuclear receptor function at natural promoters: peroxisome proliferator-activated receptor gamma agonist actions on aP2 gene expression detected using branched DNA messenger RNA quantitation.
    Burris TP, Pelton PD, Zhou L, Osborne MC, Cryan E, Demarest KT.
    Mol Endocrinol; 1999 Mar 01; 13(3):410-7. PubMed ID: 10076998
    [Abstract] [Full Text] [Related]

  • 14. Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes.
    Digby JE, Montague CT, Sewter CP, Sanders L, Wilkison WO, O'Rahilly S, Prins JB.
    Diabetes; 1998 Jan 01; 47(1):138-41. PubMed ID: 9421389
    [Abstract] [Full Text] [Related]

  • 15. Troglitazone, an antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome proliferator-activated receptor-gamma.
    Wang M, Wise SC, Leff T, Su TZ.
    Diabetes; 1999 Feb 01; 48(2):254-60. PubMed ID: 10334298
    [Abstract] [Full Text] [Related]

  • 16. Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone.
    Sakamoto J, Kimura H, Moriyama S, Odaka H, Momose Y, Sugiyama Y, Sawada H.
    Biochem Biophys Res Commun; 2000 Nov 30; 278(3):704-11. PubMed ID: 11095972
    [Abstract] [Full Text] [Related]

  • 17. Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice.
    Berger J, Bailey P, Biswas C, Cullinan CA, Doebber TW, Hayes NS, Saperstein R, Smith RG, Leibowitz MD.
    Endocrinology; 1996 Oct 30; 137(10):4189-95. PubMed ID: 8828476
    [Abstract] [Full Text] [Related]

  • 18. Thiazolidinediones stimulate uncoupling protein-2 expression in cell lines representing white and brown adipose tissues and skeletal muscle.
    Camirand A, Marie V, Rabelo R, Silva JE.
    Endocrinology; 1998 Jan 30; 139(1):428-31. PubMed ID: 9421444
    [Abstract] [Full Text] [Related]

  • 19. Differential activation of peroxisome proliferator-activated receptor-gamma by troglitazone and rosiglitazone.
    Camp HS, Li O, Wise SC, Hong YH, Frankowski CL, Shen X, Vanbogelen R, Leff T.
    Diabetes; 2000 Apr 30; 49(4):539-47. PubMed ID: 10871190
    [Abstract] [Full Text] [Related]

  • 20. Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival.
    Wang YL, Frauwirth KA, Rangwala SM, Lazar MA, Thompson CB.
    J Biol Chem; 2002 Aug 30; 277(35):31781-8. PubMed ID: 12082115
    [Abstract] [Full Text] [Related]


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