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336 related items for PubMed ID: 10908294

  • 1. The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited.
    Nakamura K, Bindokas VP, Marks JD, Wright DA, Frim DM, Miller RJ, Kang UJ.
    Mol Pharmacol; 2000 Aug; 58(2):271-8. PubMed ID: 10908294
    [Abstract] [Full Text] [Related]

  • 2. The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism.
    Lannuzel A, Michel PP, Höglinger GU, Champy P, Jousset A, Medja F, Lombès A, Darios F, Gleye C, Laurens A, Hocquemiller R, Hirsch EC, Ruberg M.
    Neuroscience; 2003 Aug; 121(2):287-96. PubMed ID: 14521988
    [Abstract] [Full Text] [Related]

  • 3. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease.
    Wang X, Su B, Liu W, He X, Gao Y, Castellani RJ, Perry G, Smith MA, Zhu X.
    Aging Cell; 2011 Oct; 10(5):807-23. PubMed ID: 21615675
    [Abstract] [Full Text] [Related]

  • 4. Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: distinct roles of superoxide anion and superoxide dismutases.
    Rodriguez-Rocha H, Garcia-Garcia A, Pickett C, Li S, Jones J, Chen H, Webb B, Choi J, Zhou Y, Zimmerman MC, Franco R.
    Free Radic Biol Med; 2013 Aug; 61():370-83. PubMed ID: 23602909
    [Abstract] [Full Text] [Related]

  • 5. Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death.
    Kim YJ, Ko HH, Han ES, Lee CS.
    Brain Res Bull; 2007 Mar 30; 71(6):633-40. PubMed ID: 17292807
    [Abstract] [Full Text] [Related]

  • 6. Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation.
    Fonck C, Baudry M.
    Brain Res; 2001 Jun 29; 905(1-2):199-206. PubMed ID: 11423095
    [Abstract] [Full Text] [Related]

  • 7. Acetylsalicylic acid and acetaminophen protect against MPP+-induced mitochondrial damage and superoxide anion generation.
    Maharaj H, Maharaj DS, Daya S.
    Life Sci; 2006 Apr 18; 78(21):2438-43. PubMed ID: 16318861
    [Abstract] [Full Text] [Related]

  • 8. Dopaminergic neurotoxicity of 1-methyl-4-phenylpyridinium analogs in cultured neurons: relationship to the dopamine uptake system and inhibition of mitochondrial respiration.
    Saporito MS, Heikkila RE, Youngster SK, Nicklas WJ, Geller HM.
    J Pharmacol Exp Ther; 1992 Mar 18; 260(3):1400-9. PubMed ID: 1312170
    [Abstract] [Full Text] [Related]

  • 9. Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons.
    Bilsland J, Roy S, Xanthoudakis S, Nicholson DW, Han Y, Grimm E, Hefti F, Harper SJ.
    J Neurosci; 2002 Apr 01; 22(7):2637-49. PubMed ID: 11923429
    [Abstract] [Full Text] [Related]

  • 10. The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity.
    Lotharius J, O'Malley KL.
    J Biol Chem; 2000 Dec 08; 275(49):38581-8. PubMed ID: 10969076
    [Abstract] [Full Text] [Related]

  • 11. Prostaglandin analogue misoprostol attenuates neurotoxin 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death in differentiated PC12 cells.
    Choi EJ, Han JH, Lee CS.
    Brain Res Bull; 2008 Nov 25; 77(5):293-300. PubMed ID: 18602972
    [Abstract] [Full Text] [Related]

  • 12. Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity.
    Ying R, Liang HL, Whelan HT, Eells JT, Wong-Riley MT.
    Brain Res; 2008 Dec 03; 1243():167-73. PubMed ID: 18848925
    [Abstract] [Full Text] [Related]

  • 13. The role of glutathione in dopaminergic neuronal survival.
    Nakamura K, Wang W, Kang UJ.
    J Neurochem; 1997 Nov 03; 69(5):1850-8. PubMed ID: 9349527
    [Abstract] [Full Text] [Related]

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  • 15. Modulation of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells by K(ATP) channel block.
    Lee CS, Kim YJ, Ko HH, Han ES.
    J Neural Transm (Vienna); 2007 Mar 03; 114(3):297-305. PubMed ID: 17109075
    [Abstract] [Full Text] [Related]

  • 16. Rosmarinic acid antagonized 1-methyl-4-phenylpyridinium (MPP+)-induced neurotoxicity in MES23.5 dopaminergic cells.
    Du T, Li L, Song N, Xie J, Jiang H.
    Int J Toxicol; 2010 Dec 03; 29(6):625-33. PubMed ID: 20966113
    [Abstract] [Full Text] [Related]

  • 17. Polyhydroxylated fullerene derivative C(60)(OH)(24) prevents mitochondrial dysfunction and oxidative damage in an MPP(+) -induced cellular model of Parkinson's disease.
    Cai X, Jia H, Liu Z, Hou B, Luo C, Feng Z, Li W, Liu J.
    J Neurosci Res; 2008 Dec 03; 86(16):3622-34. PubMed ID: 18709653
    [Abstract] [Full Text] [Related]

  • 18. 2, 2'- and 4, 4'-Cyanines are transporter-independent in vitro dopaminergic toxins with the specificity and mechanism of toxicity similar to MPP⁺.
    Kadigamuwa CC, Le VQ, Wimalasena K.
    J Neurochem; 2015 Nov 03; 135(4):755-67. PubMed ID: 26094622
    [Abstract] [Full Text] [Related]

  • 19. Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death.
    Kaul S, Anantharam V, Kanthasamy A, Kanthasamy AG.
    Brain Res Mol Brain Res; 2005 Sep 13; 139(1):137-52. PubMed ID: 15978696
    [Abstract] [Full Text] [Related]

  • 20. Neuroprotective effect of rotigotine against complex I inhibitors, MPP⁺ and rotenone, in primary mesencephalic cell culture.
    Radad K, Scheller D, Rausch WD, Reichmann H, Gille G.
    Folia Neuropathol; 2014 Sep 13; 52(2):179-86. PubMed ID: 25118903
    [Abstract] [Full Text] [Related]

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