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308 related items for PubMed ID: 10914553

  • 1. Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition.
    An WG, Hwang SG, Trepel JB, Blagosklonny MV.
    Leukemia; 2000 Jul; 14(7):1276-83. PubMed ID: 10914553
    [Abstract] [Full Text] [Related]

  • 2. Proteasome inhibitors induce p53/p21-independent apoptosis in human glioma cells.
    Wagenknecht B, Hermisson M, Eitel K, Weller M.
    Cell Physiol Biochem; 1999 Jul; 9(3):117-25. PubMed ID: 10494025
    [Abstract] [Full Text] [Related]

  • 3. Proteasome inhibitors induced caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells.
    Naujokat C, Sezer O, Zinke H, Leclere A, Hauptmann S, Possinger K.
    Eur J Haematol; 2000 Oct; 65(4):221-36. PubMed ID: 11073163
    [Abstract] [Full Text] [Related]

  • 4. Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells.
    Yu J, Tiwari S, Steiner P, Zhang L.
    Cancer Biol Ther; 2003 Oct; 2(6):694-9. PubMed ID: 14688479
    [Abstract] [Full Text] [Related]

  • 5. Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines.
    Ling YH, Liebes L, Jiang JD, Holland JF, Elliott PJ, Adams J, Muggia FM, Perez-Soler R.
    Clin Cancer Res; 2003 Mar; 9(3):1145-54. PubMed ID: 12631620
    [Abstract] [Full Text] [Related]

  • 6. F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation.
    Malashicheva AB, Kislyakova TV, Aksenov ND, Osipov KA, Pospelov VA.
    Oncogene; 2000 Aug 10; 19(34):3858-65. PubMed ID: 10951579
    [Abstract] [Full Text] [Related]

  • 7. Influence of p53 and p21Waf1 expression on G2/M phase arrest of colorectal carcinoma HCT116 cells to proteasome inhibitors.
    Kim OH, Lim JH, Woo KJ, Kim YH, Jin IN, Han ST, Park JW, Kwon TK.
    Int J Oncol; 2004 Apr 10; 24(4):935-41. PubMed ID: 15010833
    [Abstract] [Full Text] [Related]

  • 8. PS-341, a novel proteasome inhibitor, induces Bcl-2 phosphorylation and cleavage in association with G2-M phase arrest and apoptosis.
    Ling YH, Liebes L, Ng B, Buckley M, Elliott PJ, Adams J, Jiang JD, Muggia FM, Perez-Soler R.
    Mol Cancer Ther; 2002 Aug 10; 1(10):841-9. PubMed ID: 12492117
    [Abstract] [Full Text] [Related]

  • 9. Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-kappaB-dependent process.
    Dai Y, Rahmani M, Grant S.
    Oncogene; 2003 Oct 16; 22(46):7108-22. PubMed ID: 14562039
    [Abstract] [Full Text] [Related]

  • 10. Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts.
    An B, Goldfarb RH, Siman R, Dou QP.
    Cell Death Differ; 1998 Dec 16; 5(12):1062-75. PubMed ID: 9894613
    [Abstract] [Full Text] [Related]

  • 11. Proteasome-dependent regulation of p21WAF1/CIP1 expression.
    Blagosklonny MV, Wu GS, Omura S, el-Deiry WS.
    Biochem Biophys Res Commun; 1996 Oct 14; 227(2):564-9. PubMed ID: 8878553
    [Abstract] [Full Text] [Related]

  • 12. p27Kip1 accumulation by inhibition of proteasome function induces apoptosis in oral squamous cell carcinoma cells.
    Kudo Y, Takata T, Ogawa I, Kaneda T, Sato S, Takekoshi T, Zhao M, Miyauchi M, Nikai H.
    Clin Cancer Res; 2000 Mar 14; 6(3):916-23. PubMed ID: 10741716
    [Abstract] [Full Text] [Related]

  • 13. Human somatic cell knockouts reveal determinants of sensitivity and resistance to proteasome inhibitor PS-341.
    Lee C, Waldman T.
    Cancer Biol Ther; 2003 Mar 14; 2(6):700-1. PubMed ID: 14688480
    [No Abstract] [Full Text] [Related]

  • 14. Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival.
    Princiotta MF, Schubert U, Chen W, Bennink JR, Myung J, Crews CM, Yewdell JW.
    Proc Natl Acad Sci U S A; 2001 Jan 16; 98(2):513-8. PubMed ID: 11149939
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of proteasome function induced apoptosis in gastric cancer.
    Fan XM, Wong BC, Wang WP, Zhou XM, Cho CH, Yuen ST, Leung SY, Lin MC, Kung HF, Lam SK.
    Int J Cancer; 2001 Aug 15; 93(4):481-8. PubMed ID: 11477551
    [Abstract] [Full Text] [Related]

  • 16. Role of p53 in cell cycle regulation and apoptosis following exposure to proteasome inhibitors.
    Chen F, Chang D, Goh M, Klibanov SA, Ljungman M.
    Cell Growth Differ; 2000 May 15; 11(5):239-46. PubMed ID: 10845424
    [Abstract] [Full Text] [Related]

  • 17. 26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer.
    Shah SA, Potter MW, McDade TP, Ricciardi R, Perugini RA, Elliott PJ, Adams J, Callery MP.
    J Cell Biochem; 2000 May 15; 82(1):110-22. PubMed ID: 11400168
    [Abstract] [Full Text] [Related]

  • 18. Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells.
    Ling YH, Liebes L, Zou Y, Perez-Soler R.
    J Biol Chem; 2003 Sep 05; 278(36):33714-23. PubMed ID: 12821677
    [Abstract] [Full Text] [Related]

  • 19. Synergistic interaction between the novel histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in platinum-sensitive and resistant ovarian carcinoma cells.
    Gatti L, Benedetti V, De Cesare M, Corna E, Cincinelli R, Zaffaroni N, Zunino F, Perego P.
    J Inorg Biochem; 2012 Aug 05; 113():94-101. PubMed ID: 22717676
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of proteasome activity by bortezomib in renal cancer cells is p53 dependent and VHL independent.
    Vaziri SA, Grabowski DR, Hill J, Rybicki LR, Burk R, Bukowski RM, Ganapathi MK, Ganapathi R.
    Anticancer Res; 2009 Aug 05; 29(8):2961-9. PubMed ID: 19661301
    [Abstract] [Full Text] [Related]

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