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Journal Abstract Search

175 related items for PubMed ID: 10914732

  • 1. Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display.
    Beers R, Chowdhury P, Bigner D, Pastan I.
    Clin Cancer Res; 2000 Jul; 6(7):2835-43. PubMed ID: 10914732
    [Abstract] [Full Text] [Related]

  • 2. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.
    Benhar I, Padlan EA, Jung SH, Lee B, Pastan I.
    Proc Natl Acad Sci U S A; 1994 Dec 06; 91(25):12051-5. PubMed ID: 7991583
    [Abstract] [Full Text] [Related]

  • 3. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv.
    Reiter Y, Brinkmann U, Webber KO, Jung SH, Lee B, Pastan I.
    Protein Eng; 1994 May 06; 7(5):697-704. PubMed ID: 8073039
    [Abstract] [Full Text] [Related]

  • 4. Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity.
    Onda M, Nagata S, Tsutsumi Y, Vincent JJ, Wang Q, Kreitman RJ, Lee B, Pastan I.
    Cancer Res; 2001 Jul 01; 61(13):5070-7. PubMed ID: 11431343
    [Abstract] [Full Text] [Related]

  • 5. Stabilization of the Fv fragments in recombinant immunotoxins by disulfide bonds engineered into conserved framework regions.
    Reiter Y, Brinkmann U, Kreitman RJ, Jung SH, Lee B, Pastan I.
    Biochemistry; 1994 May 10; 33(18):5451-9. PubMed ID: 7910034
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  • 8. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.
    Benhar I, Pastan I.
    J Biol Chem; 1995 Oct 06; 270(40):23373-80. PubMed ID: 7559495
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  • 9. Recombinant RFB4 single-chain immunotoxin that is cytotoxic towards CD22-positive cells.
    Mansfield E, Chiron MF, Amlot P, Pastan I, FitzGerald DJ.
    Biochem Soc Trans; 1997 May 06; 25(2):709-14. PubMed ID: 9191188
    [No Abstract] [Full Text] [Related]

  • 10. Recombinant single-chain immunotoxins against T and B cell leukemias.
    Kreitman RJ, Pastan I.
    Leuk Lymphoma; 1994 Mar 06; 13(1-2):1-10. PubMed ID: 8025511
    [Abstract] [Full Text] [Related]

  • 11. Regional treatment of epidermal growth factor receptor vIII-expressing neoplastic meningitis with a single-chain immunotoxin, MR-1.
    Archer GE, Sampson JH, Lorimer IA, McLendon RE, Kuan CT, Friedman AH, Friedman HS, Pastan IH, Bigner DD.
    Clin Cancer Res; 1999 Sep 06; 5(9):2646-52. PubMed ID: 10499644
    [Abstract] [Full Text] [Related]

  • 12. A recombinant immunotoxin that is active on prostate cancer cells and that is composed of the Fv region of monoclonal antibody PR1 and a truncated form of Pseudomonas exotoxin.
    Brinkmann U, Gallo M, Brinkmann E, Kunwar S, Pastan I.
    Proc Natl Acad Sci U S A; 1993 Jan 15; 90(2):547-51. PubMed ID: 8421689
    [Abstract] [Full Text] [Related]

  • 13. Improved antitumor activity of a recombinant anti-Lewis(y) immunotoxin not requiring proteolytic activation.
    Kuan CT, Pastan I.
    Proc Natl Acad Sci U S A; 1996 Feb 06; 93(3):974-8. PubMed ID: 8577771
    [Abstract] [Full Text] [Related]

  • 14. EGF receptor and p185erbB-2-specific single-chain antibody toxins differ in their cell-killing activity on tumor cells expressing both receptor proteins.
    Wels W, Beerli R, Hellmann P, Schmidt M, Marte BM, Kornilova ES, Hekele A, Mendelsohn J, Groner B, Hynes NE.
    Int J Cancer; 1995 Jan 03; 60(1):137-44. PubMed ID: 7814146
    [Abstract] [Full Text] [Related]

  • 15. A bivalent disulfide-stabilized Fv with improved antigen binding to erbB2.
    Bera TK, Onda M, Brinkmann U, Pastan I.
    J Mol Biol; 1998 Aug 21; 281(3):475-83. PubMed ID: 9698563
    [Abstract] [Full Text] [Related]

  • 16. Characterization of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice.
    Benhar I, Pastan I.
    Clin Cancer Res; 1995 Sep 21; 1(9):1023-9. PubMed ID: 9816075
    [Abstract] [Full Text] [Related]

  • 17. Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).
    Batra JK, Fitzgerald DJ, Chaudhary VK, Pastan I.
    Mol Cell Biol; 1991 Apr 21; 11(4):2200-5. PubMed ID: 2005905
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  • 19. Design of interchain disulfide bonds in the framework region of the Fv fragment of the monoclonal antibody B3.
    Jung SH, Pastan I, Lee B.
    Proteins; 1994 May 21; 19(1):35-47. PubMed ID: 8066084
    [Abstract] [Full Text] [Related]

  • 20. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice.
    Brinkmann U, Pai LH, FitzGerald DJ, Willingham M, Pastan I.
    Proc Natl Acad Sci U S A; 1991 Oct 01; 88(19):8616-20. PubMed ID: 1924323
    [Abstract] [Full Text] [Related]

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