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Journal Abstract Search


119 related items for PubMed ID: 10933194

  • 1.
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  • 2. Dual agent chemoprotection by retroviral co-expression of either MDR1 or MRP1 with the P140K mutant of O6-methylguanine-DNA-methyl transferase.
    Southgate TD, Garside E, Margison GP, Fairbairn LJ.
    J Gene Med; 2006 Aug; 8(8):972-9. PubMed ID: 16733832
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  • 5. Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells.
    Ragg S, Xu-Welliver M, Bailey J, D'Souza M, Cooper R, Chandra S, Seshadri R, Pegg AE, Williams DA.
    Cancer Res; 2000 Sep 15; 60(18):5187-95. PubMed ID: 11016647
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  • 6. A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents.
    Jelinek J, Rafferty JA, Cmejla R, Hildinger M, Chinnasamy D, Lashford LS, Ostertag W, Margison GP, Dexter TM, Fairbairn LJ, Baum C.
    Gene Ther; 1999 Aug 15; 6(8):1489-93. PubMed ID: 10467374
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  • 7. Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells.
    Allay JA, Dumenco LL, Koc ON, Liu L, Gerson SL.
    Blood; 1995 Jun 01; 85(11):3342-51. PubMed ID: 7756667
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  • 9. Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).
    Maier P, Spier I, Laufs S, Veldwijk MR, Fruehauf S, Wenz F, Zeller WJ.
    Gene Ther; 2010 Mar 01; 17(3):389-99. PubMed ID: 19865182
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  • 10. Chemoprotective gene transfer II: multilineage in vivo protection of haemopoiesis against the effects of an antitumour agent by expression of a mutant human O6-alkylguanine-DNA alkyltransferase.
    Chinnasamy N, Rafferty JA, Hickson I, Lashford LS, Longhurst SJ, Thatcher N, Margison GP, Dexter TM, Fairbairn LJ.
    Gene Ther; 1998 Jun 01; 5(6):842-7. PubMed ID: 9747465
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  • 11. Efficient protection of cells from the genotoxicity of nitrosoureas by the retrovirus-mediated transfer of human O6-methylguanine-DNA methyltransferase using bicistronic vectors with human multidrug resistance gene 1.
    Suzuki M, Sugimoto Y, Tsuruo T.
    Mutat Res; 1998 Jun 05; 401(1-2):133-41. PubMed ID: 9639692
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  • 12. Expression of retroviral vectors containing the human multidrug resistance 1 cDNA in hematopoietic cells of transplanted mice.
    Sorrentino BP, McDonagh KT, Woods D, Orlic D.
    Blood; 1995 Jul 15; 86(2):491-501. PubMed ID: 7605985
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  • 13. Retroviral-mediated gene transduction of human alkyltransferase complementary DNA confers nitrosourea resistance to human hematopoietic progenitors.
    Allay JA, Koç ON, Davis BM, Gerson SL.
    Clin Cancer Res; 1996 Aug 15; 2(8):1353-9. PubMed ID: 9816307
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  • 18. Protection of hematopoietic cells against combined O6-benzylguanine and chloroethylnitrosourea treatment by mutant forms of O6-methylguanine DNA methyltransferase.
    Williams DA, Maze R, Kurpad C, Pegg A, Erickson LC.
    Bone Marrow Transplant; 2000 May 15; 25 Suppl 2():S105-9. PubMed ID: 10933201
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  • 19. Protection of committed murine haemopoietic progenitors against BCNU toxicity does not predict protection of primitive, multipotent spleen colony-forming cells - implications for chemoprotective gene therapy.
    Chinnasamy N, Rafferty J, Lashford L, Chinnasamy D, Margison G, Thatcher N, Dexter T, Fairbairn L.
    Leukemia; 1999 Nov 15; 13(11):1776-83. PubMed ID: 10557052
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  • 20. Retrovirus-mediated transfer of the human O6-methylguanine-DNA methyltransferase gene into a murine hematopoietic stem cell line and resistance to the toxic effects of certain alkylating agents.
    Wang G, Weiss C, Sheng P, Bresnick E.
    Biochem Pharmacol; 1996 May 03; 51(9):1221-8. PubMed ID: 8645346
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