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Journal Abstract Search

107 related items for PubMed ID: 10933885

  • 1. The decreased in vivo clearance of CYP2D6 substrates by CYP2D6*10 might be caused not only by the low-expression but also by low affinity of CYP2D6.
    Fukuda T, Nishida Y, Imaoka S, Hiroi T, Naohara M, Funae Y, Azuma J.
    Arch Biochem Biophys; 2000 Aug 15; 380(2):303-8. PubMed ID: 10933885
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  • 2. Functional analysis of CYP2D6.31 variant: homology modeling suggests possible disruption of redox partner interaction by Arg440His substitution.
    Allorge D, Bréant D, Harlow J, Chowdry J, Lo-Guidice JM, Chevalier D, Cauffiez C, Lhermitte M, Blaney FE, Tucker GT, Broly F, Ellis SW.
    Proteins; 2005 May 01; 59(2):339-46. PubMed ID: 15726636
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  • 3. CYP2D6.10 present in human liver microsomes shows low catalytic activity and thermal stability.
    Nakamura K, Ariyoshi N, Yokoi T, Ohgiya S, Chida M, Nagashima K, Inoue K, Kodama T, Shimada N, Kamataki T.
    Biochem Biophys Res Commun; 2002 May 10; 293(3):969-73. PubMed ID: 12051754
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  • 4. Effect of genetic polymorphism on the metabolism of endogenous neuroactive substances, progesterone and p-tyramine, catalyzed by CYP2D6.
    Niwa T, Hiroi T, Tsuzuki D, Yamamoto S, Narimatsu S, Fukuda T, Azuma J, Funae Y.
    Brain Res Mol Brain Res; 2004 Oct 22; 129(1-2):117-23. PubMed ID: 15469888
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  • 5. Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity.
    Wan J, Imaoka S, Chow T, Hiroi T, Yabusaki Y, Funae Y.
    Arch Biochem Biophys; 1997 Dec 15; 348(2):383-90. PubMed ID: 9434752
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  • 6. Two novel CYP2D6*10 haplotypes as possible causes of a poor metabolic phenotype in Japanese.
    Matsunaga M, Yamazaki H, Kiyotani K, Iwano S, Saruwatari J, Nakagawa K, Soyama A, Ozawa S, Sawada J, Kashiyama E, Kinoshita M, Kamataki T.
    Drug Metab Dispos; 2009 Apr 15; 37(4):699-701. PubMed ID: 19158312
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  • 7. Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6.1, 2D6.2, 2D6.10, and 2D6.17 allelic isoforms.
    Yu A, Kneller BM, Rettie AE, Haining RL.
    J Pharmacol Exp Ther; 2002 Dec 15; 303(3):1291-300. PubMed ID: 12438554
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  • 8. Molecular cloning, expression, and characterization of CYP2D17 from cynomolgus monkey liver.
    Mankowski DC, Laddison KJ, Christopherson PA, Ekins S, Tweedie DJ, Lawton MP.
    Arch Biochem Biophys; 1999 Dec 01; 372(1):189-96. PubMed ID: 10562433
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  • 9. The role of phenylalanine 483 in cytochrome P450 2D6 is strongly substrate dependent.
    Lussenburg BM, Keizers PH, de Graaf C, Hidestrand M, Ingelman-Sundberg M, Vermeulen NP, Commandeur JN.
    Biochem Pharmacol; 2005 Oct 15; 70(8):1253-61. PubMed ID: 16135359
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  • 12. Dopamine formation from tyramine by CYP2D6.
    Hiroi T, Imaoka S, Funae Y.
    Biochem Biophys Res Commun; 1998 Aug 28; 249(3):838-43. PubMed ID: 9731223
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  • 13. Characterization of dextromethorphan O- and N-demethylation catalyzed by highly purified recombinant human CYP2D6.
    Yu A, Dong H, Lang D, Haining RL.
    Drug Metab Dispos; 2001 Nov 28; 29(11):1362-5. PubMed ID: 11602510
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  • 16. Impaired expression of CYP2D6 in intermediate metabolizers carrying the *41 allele caused by the intronic SNP 2988G>A: evidence for modulation of splicing events.
    Toscano C, Klein K, Blievernicht J, Schaeffeler E, Saussele T, Raimundo S, Eichelbaum M, Schwab M, Zanger UM.
    Pharmacogenet Genomics; 2006 Oct 28; 16(10):755-66. PubMed ID: 17001295
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  • 17. Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects.
    Maekawa K, Harakawa N, Sugiyama E, Tohkin M, Kim SR, Kaniwa N, Katori N, Hasegawa R, Yasuda K, Kamide K, Miyata T, Saito Y, Sawada J.
    Drug Metab Dispos; 2009 Sep 28; 37(9):1895-903. PubMed ID: 19541829
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  • 18. Influence of phenylalanine 120 on cytochrome P450 2D6 catalytic selectivity and regiospecificity: crucial role in 7-methoxy-4-(aminomethyl)-coumarin metabolism.
    Keizers PH, Lussenburg BM, de Graaf C, Mentink LM, Vermeulen NP, Commandeur JN.
    Biochem Pharmacol; 2004 Dec 01; 68(11):2263-71. PubMed ID: 15498516
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  • 19. Expression, purification, and biochemical characterization of a human cytochrome P450 CYP2D6-NADPH cytochrome P450 reductase fusion protein.
    Deeni YY, Paine MJ, Ayrton AD, Clarke SE, Chenery R, Wolf CR.
    Arch Biochem Biophys; 2001 Dec 01; 396(1):16-24. PubMed ID: 11716457
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  • 20. Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes.
    Hanioka N, Yamamoto M, Iwabu H, Jinno H, Tanaka-Kagawa T, Naito S, Shimizu T, Masuda K, Katsu T, Narimatsu S.
    Life Sci; 2007 Oct 27; 81(19-20):1436-45. PubMed ID: 17935737
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