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162 related items for PubMed ID: 10945864

  • 1. Uptake of imipramine in rat liver lysosomes in vitro and its inhibition by basic drugs.
    Ishizaki J, Yokogawa K, Ichimura F, Ohkuma S.
    J Pharmacol Exp Ther; 2000 Sep; 294(3):1088-98. PubMed ID: 10945864
    [Abstract] [Full Text] [Related]

  • 2. Saturable uptake of lipophilic amine drugs into isolated hepatocytes: mechanisms and consequences for quantitative clearance prediction.
    Hallifax D, Houston JB.
    Drug Metab Dispos; 2007 Aug; 35(8):1325-32. PubMed ID: 17470525
    [Abstract] [Full Text] [Related]

  • 3. Interactions between promazine and antidepressants at the level of cellular distribution.
    Daniel WA, Wójcikowski J.
    Pharmacol Toxicol; 1997 Dec; 81(6):259-64. PubMed ID: 9444666
    [Abstract] [Full Text] [Related]

  • 4. The role of a transmembrane pH gradient in uptake and release of imipramine and haloperidol in synaptosomes.
    Schmalzing G.
    Mol Pharmacol; 1988 Dec; 34(6):888-95. PubMed ID: 3200251
    [Abstract] [Full Text] [Related]

  • 5. Uptake and intracellular binding of lipophilic amine drugs by isolated rat hepatocytes and implications for prediction of in vivo metabolic clearance.
    Hallifax D, Houston JB.
    Drug Metab Dispos; 2006 Nov; 34(11):1829-36. PubMed ID: 16882765
    [Abstract] [Full Text] [Related]

  • 6. Contribution of lysosomes to the subcellular distribution of basic drugs in the rat liver.
    Ishizaki J, Yokogawa K, Hirano M, Nakashima E, Sai Y, Ohkuma S, Ohshima T, Ichimura F.
    Pharm Res; 1996 Jun; 13(6):902-6. PubMed ID: 8792430
    [Abstract] [Full Text] [Related]

  • 7. Characteristics of taurine transport in rat liver lysosomes.
    Vadgama JV, Chang K, Kopple JD, Idriss JM, Jonas AJ.
    J Cell Physiol; 1991 Jun; 147(3):447-54. PubMed ID: 2066365
    [Abstract] [Full Text] [Related]

  • 8. ATP-induced stimulation of the intralysosomal hydrolysis of thyroglobulin. Evidence for an ATP-driven proton pump in thyroid lysosomes.
    Fouchier F, Mego JL, Dang J, Simon C.
    Horm Metab Res; 1984 Jul; 16(7):359-62. PubMed ID: 6092251
    [Abstract] [Full Text] [Related]

  • 9. Energy-dependent accumulation of neuron blockers causes selective inhibition of neurotransmitter uptake by brain synaptic vesicles.
    Moriyama Y, Tsai HL, Futai M.
    Arch Biochem Biophys; 1993 Sep; 305(2):278-81. PubMed ID: 8373165
    [Abstract] [Full Text] [Related]

  • 10. Influence of lipophilicity and lysosomal accumulation on tissue distribution kinetics of basic drugs: a physiologically based pharmacokinetic model.
    Yokogawa K, Ishizaki J, Ohkuma S, Miyamoto K.
    Methods Find Exp Clin Pharmacol; 2002 Mar; 24(2):81-93. PubMed ID: 12040887
    [Abstract] [Full Text] [Related]

  • 11. Quantitation of the lysosomotropic character of cationic amphiphilic drugs using the fluorescent basic amine Red DND-99.
    Lemieux B, Percival MD, Falgueyret JP.
    Anal Biochem; 2004 Apr 15; 327(2):247-51. PubMed ID: 15051542
    [Abstract] [Full Text] [Related]

  • 12. Active uptake of propranolol by isolated rabbit alveolar macrophages and its inhibition by other basic amines.
    Vestal RE, Kornhauser DM, Shand DG.
    J Pharmacol Exp Ther; 1980 Jul 15; 214(1):106-11. PubMed ID: 7391962
    [Abstract] [Full Text] [Related]

  • 13. Ion-trapping, microsomal binding, and unbound drug distribution in the hepatic retention of basic drugs.
    Siebert GA, Hung DY, Chang P, Roberts MS.
    J Pharmacol Exp Ther; 2004 Jan 15; 308(1):228-35. PubMed ID: 14566005
    [Abstract] [Full Text] [Related]

  • 14. [Studies on the mechanism of subcellular distribution of basic drugs based on their lipophilicity].
    Ishizaki J, Yokogawa K, Ohkuma S, Ichimura F, Miyamoto K.
    Yakugaku Zasshi; 2001 Jul 15; 121(7):557-65. PubMed ID: 11494600
    [Abstract] [Full Text] [Related]

  • 15. ATP-dependent lysis of isolated lysosomes by basic substances and acidic ionophores.
    Ohkuma S, Takano T.
    Cell Struct Funct; 1997 Apr 15; 22(2):253-68. PubMed ID: 9195051
    [Abstract] [Full Text] [Related]

  • 16. Lipophilic cationic drugs increase the permeability of lysosomal membranes in a cell culture system.
    Kornhuber J, Henkel AW, Groemer TW, Städtler S, Welzel O, Tripal P, Rotter A, Bleich S, Trapp S.
    J Cell Physiol; 2010 Jul 15; 224(1):152-64. PubMed ID: 20301195
    [Abstract] [Full Text] [Related]

  • 17. Effect of cationic surfactant on transport of surface-active and non-surface-active model drugs and emulsion stability in triphasic systems.
    Chidambaram N, Burgess DJ.
    AAPS PharmSci; 2000 Jul 15; 2(3):E28. PubMed ID: 11741244
    [Abstract] [Full Text] [Related]

  • 18. Effect of hyperoxia on imipramine uptake and metabolism by the isolated, perfused rat lung.
    Block ER, Cannon JK.
    Res Commun Chem Pathol Pharmacol; 1978 Dec 15; 22(3):621-4. PubMed ID: 734241
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of weak-base amine-induced lysis of lysosomes by cytosol.
    Arai K, Yasuda N, Isohashi F, Okamoto K, Ohkuma S.
    J Biochem; 2002 Oct 15; 132(4):529-34. PubMed ID: 12359066
    [Abstract] [Full Text] [Related]

  • 20. Heavy metal detoxification in crustacean epithelial lysosomes: role of anions in the compartmentalization process.
    Sterling KM, Mandal PK, Roggenbeck BA, Ahearn SE, Gerencser GA, Ahearn GA.
    J Exp Biol; 2007 Oct 15; 210(Pt 19):3484-93. PubMed ID: 17873002
    [Abstract] [Full Text] [Related]

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