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241 related items for PubMed ID: 10952971
1. Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum. Shakur Y, Takeda K, Kenan Y, Yu ZX, Rena G, Brandt D, Houslay MD, Degerman E, Ferrans VJ, Manganiello VC. J Biol Chem; 2000 Dec 08; 275(49):38749-61. PubMed ID: 10952971 [Abstract] [Full Text] [Related]
2. Functions of the N-terminal region of cyclic nucleotide phosphodiesterase 3 (PDE 3) isoforms. Kenan Y, Murata T, Shakur Y, Degerman E, Manganiello VC. J Biol Chem; 2000 Apr 21; 275(16):12331-8. PubMed ID: 10766874 [Abstract] [Full Text] [Related]
3. Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. Ahmad F, Lindh R, Tang Y, Weston M, Degerman E, Manganiello VC. Biochem J; 2007 Jun 01; 404(2):257-68. PubMed ID: 17324123 [Abstract] [Full Text] [Related]
4. In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting. Beard MB, Huston E, Campbell L, Gall I, McPhee I, Yarwood S, Scotland G, Houslay MD. Cell Signal; 2002 May 01; 14(5):453-65. PubMed ID: 11882390 [Abstract] [Full Text] [Related]
5. Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardium. Hambleton R, Krall J, Tikishvili E, Honeggar M, Ahmad F, Manganiello VC, Movsesian MA. J Biol Chem; 2005 Nov 25; 280(47):39168-74. PubMed ID: 16172121 [Abstract] [Full Text] [Related]
6. Characterization of two recombinant PDE3 (cGMP-inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells. Leroy MJ, Degerman E, Taira M, Murata T, Wang LH, Movsesian MA, Meacci E, Manganiello VC. Biochemistry; 1996 Aug 06; 35(31):10194-202. PubMed ID: 8756484 [Abstract] [Full Text] [Related]
7. Expression of cyclic GMP-inhibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: differential subcellular localization and regulated expression by cyclic AMP. Liu H, Maurice DH. Br J Pharmacol; 1998 Dec 06; 125(7):1501-10. PubMed ID: 9884079 [Abstract] [Full Text] [Related]
8. Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene. Johnston LA, Erdogan S, Cheung YF, Sullivan M, Barber R, Lynch MJ, Baillie GS, Van Heeke G, Adams DR, Huston E, Houslay MD. Biochem J; 2004 Jun 01; 380(Pt 2):371-84. PubMed ID: 15025561 [Abstract] [Full Text] [Related]
9. Expression and mutagenesis of the catalytic domain of cGMP-inhibited phosphodiesterase (PDE3) cloned from human platelets. Tang KM, Jang EK, Haslam RJ. Biochem J; 1997 Apr 01; 323 ( Pt 1)(Pt 1):217-24. PubMed ID: 9173884 [Abstract] [Full Text] [Related]
10. TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid. Baillie GS, Huston E, Scotland G, Hodgkin M, Gall I, Peden AH, MacKenzie C, Houslay ES, Currie R, Pettitt TR, Walmsley AR, Wakelam MJ, Warwicker J, Houslay MD. J Biol Chem; 2002 Aug 02; 277(31):28298-309. PubMed ID: 11994273 [Abstract] [Full Text] [Related]
11. Isoforms of cyclic nucleotide phosphodiesterase PDE3A in cardiac myocytes. Wechsler J, Choi YH, Krall J, Ahmad F, Manganiello VC, Movsesian MA. J Biol Chem; 2002 Oct 11; 277(41):38072-8. PubMed ID: 12154085 [Abstract] [Full Text] [Related]
12. Identification of overlapping but distinct cAMP and cGMP interaction sites with cyclic nucleotide phosphodiesterase 3A by site-directed mutagenesis and molecular modeling based on crystalline PDE4B. Zhang W, Ke H, Tretiakova AP, Jameson B, Colman RW. Protein Sci; 2001 Aug 11; 10(8):1481-9. PubMed ID: 11468344 [Abstract] [Full Text] [Related]
13. Plasma membrane cyclic nucleotide phosphodiesterase 3B (PDE3B) is associated with caveolae in primary adipocytes. Nilsson R, Ahmad F, Swärd K, Andersson U, Weston M, Manganiello V, Degerman E. Cell Signal; 2006 Oct 11; 18(10):1713-21. PubMed ID: 16503395 [Abstract] [Full Text] [Related]
14. Cyclic AMP phosphodiesterases in human lymphocytes. Sheth SB, Chaganti K, Bastepe M, Ajuria J, Brennan K, Biradavolu R, Colman RW. Br J Haematol; 1997 Dec 11; 99(4):784-9. PubMed ID: 9432022 [Abstract] [Full Text] [Related]
15. Identification of inhibitor specificity determinants in a mammalian phosphodiesterase. Atienza JM, Susanto D, Huang C, McCarty AS, Colicelli J. J Biol Chem; 1999 Feb 19; 274(8):4839-47. PubMed ID: 9988724 [Abstract] [Full Text] [Related]
16. Chimeric constructs show that the unique N-terminal domain of the cyclic AMP phosphodiesterase RD1 (RNPDE4A1A; rPDE-IVA1) can confer membrane association upon the normally cytosolic protein chloramphenicol acetyltransferase. Scotland G, Houslay MD. Biochem J; 1995 Jun 01; 308 ( Pt 2)(Pt 2):673-81. PubMed ID: 7772057 [Abstract] [Full Text] [Related]
17. Determination of the structure of the N-terminal splice region of the cyclic AMP-specific phosphodiesterase RD1 (RNPDE4A1) by 1H NMR and identification of the membrane association domain using chimeric constructs. Smith KJ, Scotland G, Beattie J, Trayer IP, Houslay MD. J Biol Chem; 1996 Jul 12; 271(28):16703-11. PubMed ID: 8663181 [Abstract] [Full Text] [Related]
18. Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+. Huston E, Gall I, Houslay TM, Houslay MD. J Cell Sci; 2006 Sep 15; 119(Pt 18):3799-810. PubMed ID: 16940352 [Abstract] [Full Text] [Related]
19. PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6). Cheung YF, Kan Z, Garrett-Engele P, Gall I, Murdoch H, Baillie GS, Camargo LM, Johnson JM, Houslay MD, Castle JC. J Pharmacol Exp Ther; 2007 Aug 15; 322(2):600-9. PubMed ID: 17519386 [Abstract] [Full Text] [Related]
20. The transmembrane region of microsomal cytochrome P450 identified as the endoplasmic reticulum retention signal. Murakami K, Mihara K, Omura T. J Biochem; 1994 Jul 15; 116(1):164-75. PubMed ID: 7798174 [Abstract] [Full Text] [Related] Page: [Next] [New Search]