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PUBMED FOR HANDHELDS

Journal Abstract Search


302 related items for PubMed ID: 10962093

  • 1. Two transport binding sites of P-glycoprotein are unequal yet contingent: initial rate kinetic analysis by ATP hydrolysis demonstrates intersite dependence.
    Wang EJ, Casciano CN, Clement RP, Johnson WW.
    Biochim Biophys Acta; 2000 Aug 31; 1481(1):63-74. PubMed ID: 10962093
    [Abstract] [Full Text] [Related]

  • 2. Proximity of bound Hoechst 33342 to the ATPase catalytic sites places the drug binding site of P-glycoprotein within the cytoplasmic membrane leaflet.
    Qu Q, Sharom FJ.
    Biochemistry; 2002 Apr 09; 41(14):4744-52. PubMed ID: 11926837
    [Abstract] [Full Text] [Related]

  • 3. Competitive and non-competitive inhibition of the multidrug-resistance-associated P-glycoprotein ATPase--further experimental evidence for a multisite model.
    Garrigos M, Mir LM, Orlowski S.
    Eur J Biochem; 1997 Mar 01; 244(2):664-73. PubMed ID: 9119038
    [Abstract] [Full Text] [Related]

  • 4. Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.
    Li MJ, Nath A, Atkins WM.
    Biochemistry; 2017 May 16; 56(19):2506-2517. PubMed ID: 28441502
    [Abstract] [Full Text] [Related]

  • 5. Stoichiometry of coupling of rhodamine 123 transport to ATP hydrolysis by P-glycoprotein.
    Shapiro AB, Ling V.
    Eur J Biochem; 1998 May 15; 254(1):189-93. PubMed ID: 9652413
    [Abstract] [Full Text] [Related]

  • 6. P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer.
    Shapiro AB, Corder AB, Ling V.
    Eur J Biochem; 1997 Nov 15; 250(1):115-21. PubMed ID: 9431998
    [Abstract] [Full Text] [Related]

  • 7. Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter.
    Romsicki Y, Sharom FJ.
    Biochemistry; 2001 Jun 12; 40(23):6937-47. PubMed ID: 11389609
    [Abstract] [Full Text] [Related]

  • 8. Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities.
    Shapiro AB, Ling V.
    Eur J Biochem; 1997 Nov 15; 250(1):130-7. PubMed ID: 9432000
    [Abstract] [Full Text] [Related]

  • 9. Multiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1).
    Chufan EE, Kapoor K, Sim HM, Singh S, Talele TT, Durell SR, Ambudkar SV.
    PLoS One; 2013 Nov 15; 8(12):e82463. PubMed ID: 24349290
    [Abstract] [Full Text] [Related]

  • 10. Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.
    Shapiro AB, Fox K, Lam P, Ling V.
    Eur J Biochem; 1999 Feb 15; 259(3):841-50. PubMed ID: 10092872
    [Abstract] [Full Text] [Related]

  • 11. Communication between multiple drug binding sites on P-glycoprotein.
    Martin C, Berridge G, Higgins CF, Mistry P, Charlton P, Callaghan R.
    Mol Pharmacol; 2000 Sep 15; 58(3):624-32. PubMed ID: 10953057
    [Abstract] [Full Text] [Related]

  • 12. Transport of LDS-751 from the cytoplasmic leaflet of the plasma membrane by the rhodamine-123-selective site of P-glycoprotein.
    Shapiro AB, Ling V.
    Eur J Biochem; 1998 May 15; 254(1):181-8. PubMed ID: 9652412
    [Abstract] [Full Text] [Related]

  • 13. Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.
    Wang EJ, Casciano CN, Clement RP, Johnson WW.
    Pharm Res; 2003 Apr 15; 20(4):537-44. PubMed ID: 12739759
    [Abstract] [Full Text] [Related]

  • 14. Functional studies of P-glycoprotein in inside-out plasma membrane vesicles derived from murine erythroleukemia cells overexpressing MDR 3. Properties and kinetics of the interaction of vinblastine with P-glycoprotein and evidence for its active mediated transport.
    Schlemmer SR, Sirotnak FM.
    J Biol Chem; 1994 Dec 09; 269(49):31059-66. PubMed ID: 7983045
    [Abstract] [Full Text] [Related]

  • 15. Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
    Pascaud C, Garrigos M, Orlowski S.
    Biochem J; 1998 Jul 15; 333 ( Pt 2)(Pt 2):351-8. PubMed ID: 9657975
    [Abstract] [Full Text] [Related]

  • 16. Drug binding sites on P-glycoprotein are altered by ATP binding prior to nucleotide hydrolysis.
    Martin C, Berridge G, Mistry P, Higgins C, Charlton P, Callaghan R.
    Biochemistry; 2000 Oct 03; 39(39):11901-6. PubMed ID: 11009602
    [Abstract] [Full Text] [Related]

  • 17. Uncoupled active transport mechanisms accounting for low selectivity in multidrug carriers: P-glycoprotein and SMR antiporters.
    Krupka RM.
    J Membr Biol; 1999 Nov 15; 172(2):129-43. PubMed ID: 10556361
    [Abstract] [Full Text] [Related]

  • 18. The role of P-glycoprotein in intestinal transport versus the BBB transport of tetraphenylphosphonium.
    Swed A, Eyal S, Madar I, Zohar-Kontante H, Weiss L, Hoffman A.
    Mol Pharm; 2009 Nov 15; 6(6):1883-90. PubMed ID: 19722701
    [Abstract] [Full Text] [Related]

  • 19. Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.
    Ramachandra M, Ambudkar SV, Gottesman MM, Pastan I, Hrycyna CA.
    Mol Biol Cell; 1996 Oct 15; 7(10):1485-98. PubMed ID: 8898356
    [Abstract] [Full Text] [Related]

  • 20. Linear and cyclic peptides as substrates and modulators of P-glycoprotein: peptide binding and effects on drug transport and accumulation.
    Sharom FJ, Lu P, Liu R, Yu X.
    Biochem J; 1998 Aug 01; 333 ( Pt 3)(Pt 3):621-30. PubMed ID: 9677321
    [Abstract] [Full Text] [Related]


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