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366 related items for PubMed ID: 10964504

  • 1. NGF-Dependent neurite outgrowth in PC12 cells overexpressing the Src homology 2-domain protein shb requires activation of the Rap1 pathway.
    Lu L, Annerén C, Reedquist KA, Bos JL, Welsh M.
    Exp Cell Res; 2000 Sep 15; 259(2):370-7. PubMed ID: 10964504
    [Abstract] [Full Text] [Related]

  • 2. Sustained activation of M-Ras induced by nerve growth factor is essential for neuronal differentiation of PC12 cells.
    Sun P, Watanabe H, Takano K, Yokoyama T, Fujisawa J, Endo T.
    Genes Cells; 2006 Sep 15; 11(9):1097-113. PubMed ID: 16923128
    [Abstract] [Full Text] [Related]

  • 3. The Src homology 2 domain protein Shb transmits basic fibroblast growth factor- and nerve growth factor-dependent differentiation signals in PC12 cells.
    Karlsson T, Kullander K, Welsh M.
    Cell Growth Differ; 1998 Sep 15; 9(9):757-66. PubMed ID: 9751119
    [Abstract] [Full Text] [Related]

  • 4. GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase.
    Annerén C, Reedquist KA, Bos JL, Welsh M.
    J Biol Chem; 2000 Sep 15; 275(37):29153-61. PubMed ID: 10878015
    [Abstract] [Full Text] [Related]

  • 5. p190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells.
    Jeon CY, Kim HJ, Lee JY, Kim JB, Kim SC, Park JB.
    Exp Mol Med; 2010 May 31; 42(5):335-44. PubMed ID: 20200473
    [Abstract] [Full Text] [Related]

  • 6. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
    York RD, Yao H, Dillon T, Ellig CL, Eckert SP, McCleskey EW, Stork PJ.
    Nature; 1998 Apr 09; 392(6676):622-6. PubMed ID: 9560161
    [Abstract] [Full Text] [Related]

  • 7. PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells.
    Obara Y, Labudda K, Dillon TJ, Stork PJ.
    J Cell Sci; 2004 Dec 01; 117(Pt 25):6085-94. PubMed ID: 15546918
    [Abstract] [Full Text] [Related]

  • 8. Hierarchical analysis of the nerve growth factor-dependent and nerve growth factor-independent differentiation signaling pathways in PC12 cells with protein kinase inhibitors.
    Campbell XZ, Neet KE.
    J Neurosci Res; 1995 Oct 01; 42(2):207-19. PubMed ID: 8568921
    [Abstract] [Full Text] [Related]

  • 9. Role of the Src homology 2 domain-containing protein Shb in murine brain endothelial cell proliferation and differentiation.
    Lu L, Holmqvist K, Cross M, Welsh M.
    Cell Growth Differ; 2002 Mar 01; 13(3):141-8. PubMed ID: 11959815
    [Abstract] [Full Text] [Related]

  • 10. Induction of neurite outgrowth in PC12 cells by gamma-lactam-related compounds via Ras-MAP kinase signaling pathway independent mechanism.
    Yao R, Osada H.
    Exp Cell Res; 1997 Aug 01; 234(2):233-9. PubMed ID: 9260890
    [Abstract] [Full Text] [Related]

  • 11. Regulation of the Ras signaling pathway by GTPase-activating protein in PC12 cells.
    Yao R, Cooper GM.
    Oncogene; 1995 Oct 19; 11(8):1607-14. PubMed ID: 7478585
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  • 13. Control of neurite outgrowth by RhoA inactivation.
    Jeon CY, Moon MY, Kim JH, Kim HJ, Kim JG, Li Y, Jin JK, Kim PH, Kim HC, Meier KE, Kim YS, Park JB.
    J Neurochem; 2012 Mar 19; 120(5):684-98. PubMed ID: 22035369
    [Abstract] [Full Text] [Related]

  • 14. Modulation of Src homology 3 proteins by the proline-rich adaptor protein Shb.
    Karlsson T, Welsh M.
    Exp Cell Res; 1997 Mar 15; 231(2):269-75. PubMed ID: 9087167
    [Abstract] [Full Text] [Related]

  • 15. Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase.
    Uchida M, Enomoto A, Fukuda T, Kurokawa K, Maeda K, Kodama Y, Asai N, Hasegawa T, Shimono Y, Jijiwa M, Ichihara M, Murakumo Y, Takahashi M.
    J Cell Sci; 2006 Aug 01; 119(Pt 15):3067-77. PubMed ID: 16820412
    [Abstract] [Full Text] [Related]

  • 16. PACAP activates Rac1 and synergizes with NGF to activate ERK1/2, thereby inducing neurite outgrowth in PC12 cells.
    Sakai Y, Hashimoto H, Shintani N, Katoh H, Negishi M, Kawaguchi C, Kasai A, Baba A.
    Brain Res Mol Brain Res; 2004 Apr 07; 123(1-2):18-26. PubMed ID: 15046862
    [Abstract] [Full Text] [Related]

  • 17. Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells.
    Schönherr C, Yang HL, Vigny M, Palmer RH, Hallberg B.
    Oncogene; 2010 May 13; 29(19):2817-30. PubMed ID: 20190816
    [Abstract] [Full Text] [Related]

  • 18. Spatio-temporal images of growth-factor-induced activation of Ras and Rap1.
    Mochizuki N, Yamashita S, Kurokawa K, Ohba Y, Nagai T, Miyawaki A, Matsuda M.
    Nature; 2001 Jun 28; 411(6841):1065-8. PubMed ID: 11429608
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