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360 related items for PubMed ID: 10967078

  • 1. VEGF is major stimulator in model of choroidal neovascularization.
    Kwak N, Okamoto N, Wood JM, Campochiaro PA.
    Invest Ophthalmol Vis Sci; 2000 Sep; 41(10):3158-64. PubMed ID: 10967078
    [Abstract] [Full Text] [Related]

  • 2. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.
    Wood JM, Bold G, Buchdunger E, Cozens R, Ferrari S, Frei J, Hofmann F, Mestan J, Mett H, O'Reilly T, Persohn E, Rösel J, Schnell C, Stover D, Theuer A, Towbin H, Wenger F, Woods-Cook K, Menrad A, Siemeister G, Schirner M, Thierauch KH, Schneider MR, Drevs J, Martiny-Baron G, Totzke F.
    Cancer Res; 2000 Apr 15; 60(8):2178-89. PubMed ID: 10786682
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of vascular endothelial growth factor (VEGF) as a novel approach for cancer therapy.
    Wood JM.
    Medicina (B Aires); 2000 Apr 15; 60 Suppl 2():41-7. PubMed ID: 11188930
    [Abstract] [Full Text] [Related]

  • 4. Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation.
    Yano S, Herbst RS, Shinohara H, Knighton B, Bucana CD, Killion JJ, Wood J, Fidler IJ.
    Clin Cancer Res; 2000 Mar 15; 6(3):957-65. PubMed ID: 10741721
    [Abstract] [Full Text] [Related]

  • 5. Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization.
    Ozaki H, Seo MS, Ozaki K, Yamada H, Yamada E, Okamoto N, Hofmann F, Wood JM, Campochiaro PA.
    Am J Pathol; 2000 Feb 15; 156(2):697-707. PubMed ID: 10666398
    [Abstract] [Full Text] [Related]

  • 6. Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF- and basic fibroblast growth factor-induced angiogenesis in vivo and in vitro.
    Tille JC, Wood J, Mandriota SJ, Schnell C, Ferrari S, Mestan J, Zhu Z, Witte L, Pepper MS.
    J Pharmacol Exp Ther; 2001 Dec 15; 299(3):1073-85. PubMed ID: 11714897
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of protein kinase C decreases prostaglandin-induced breakdown of the blood-retinal barrier.
    Saishin Y, Saishin Y, Takahashi K, Melia M, Vinores SA, Campochiaro PA.
    J Cell Physiol; 2003 May 15; 195(2):210-9. PubMed ID: 12652648
    [Abstract] [Full Text] [Related]

  • 8. Suppression of choroidal neovascularization by inhibiting angiotensin-converting enzyme: minimal role of bradykinin.
    Nagai N, Oike Y, Izumi-Nagai K, Koto T, Satofuka S, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Ishida S.
    Invest Ophthalmol Vis Sci; 2007 May 15; 48(5):2321-6. PubMed ID: 17460297
    [Abstract] [Full Text] [Related]

  • 9. Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor.
    Lu D, Jimenez X, Zhang H, Wu Y, Bohlen P, Witte L, Zhu Z.
    Cancer Res; 2001 Oct 01; 61(19):7002-8. PubMed ID: 11585724
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.
    Economou MA, Wu J, Vasilcanu D, Rosengren L, All-Ericsson C, van der Ploeg I, Menu E, Girnita L, Axelson M, Larsson O, Seregard S, Kvanta A.
    Invest Ophthalmol Vis Sci; 2008 Jun 01; 49(6):2620-6. PubMed ID: 18515591
    [Abstract] [Full Text] [Related]

  • 11. Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor.
    Smith LE, Shen W, Perruzzi C, Soker S, Kinose F, Xu X, Robinson G, Driver S, Bischoff J, Zhang B, Schaeffer JM, Senger DR.
    Nat Med; 1999 Dec 01; 5(12):1390-5. PubMed ID: 10581081
    [Abstract] [Full Text] [Related]

  • 12. Transforming growth factor-beta induces expression of vascular endothelial growth factor in human retinal pigment epithelial cells: involvement of mitogen-activated protein kinases.
    Nagineni CN, Samuel W, Nagineni S, Pardhasaradhi K, Wiggert B, Detrick B, Hooks JJ.
    J Cell Physiol; 2003 Dec 01; 197(3):453-62. PubMed ID: 14566975
    [Abstract] [Full Text] [Related]

  • 13. The adapter protein, Grb10, is a positive regulator of vascular endothelial growth factor signaling.
    Giorgetti-Peraldi S, Murdaca J, Mas JC, Van Obberghen E.
    Oncogene; 2001 Jul 05; 20(30):3959-68. PubMed ID: 11494124
    [Abstract] [Full Text] [Related]

  • 14. Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice.
    Blaskovich MA, Lin Q, Delarue FL, Sun J, Park HS, Coppola D, Hamilton AD, Sebti SM.
    Nat Biotechnol; 2000 Oct 05; 18(10):1065-70. PubMed ID: 11017044
    [Abstract] [Full Text] [Related]

  • 15. Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves radiation tumor therapy.
    Timke C, Zieher H, Roth A, Hauser K, Lipson KE, Weber KJ, Debus J, Abdollahi A, Huber PE.
    Clin Cancer Res; 2008 Apr 01; 14(7):2210-9. PubMed ID: 18381963
    [Abstract] [Full Text] [Related]

  • 16. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.
    Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J, Tolentino MJ.
    Mol Vis; 2003 May 30; 9():210-6. PubMed ID: 12789138
    [Abstract] [Full Text] [Related]

  • 17. Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice.
    Brekken RA, Overholser JP, Stastny VA, Waltenberger J, Minna JD, Thorpe PE.
    Cancer Res; 2000 Sep 15; 60(18):5117-24. PubMed ID: 11016638
    [Abstract] [Full Text] [Related]

  • 18. Vascular endothelial growth factor- and platelet-derived growth factor-angiogenesis depressed but fetal bovine serum-angiogenesis enhanced choroidal tissue cultures of streptozotocin-diabetic Wistar and GK rats.
    Kimura I, Yanagita S, Kobayshi S, Fukuta M, Okabe M.
    Int Angiol; 2000 Mar 15; 19(1):26-34. PubMed ID: 10853682
    [Abstract] [Full Text] [Related]

  • 19. VEGF-induced activation of phosphoinositide 3-kinase is dependent on focal adhesion kinase.
    Qi JH, Claesson-Welsh L.
    Exp Cell Res; 2001 Feb 01; 263(1):173-82. PubMed ID: 11161716
    [Abstract] [Full Text] [Related]

  • 20. Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth.
    Hess C, Vuong V, Hegyi I, Riesterer O, Wood J, Fabbro D, Glanzmann C, Bodis S, Pruschy M.
    Br J Cancer; 2001 Dec 14; 85(12):2010-6. PubMed ID: 11747347
    [Abstract] [Full Text] [Related]

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