These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

269 related items for PubMed ID: 10973971

  • 1. Degradation of amylin by insulin-degrading enzyme.
    Bennett RG, Duckworth WC, Hamel FG.
    J Biol Chem; 2000 Nov 24; 275(47):36621-5. PubMed ID: 10973971
    [Abstract] [Full Text] [Related]

  • 2. An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures.
    Bennett RG, Hamel FG, Duckworth WC.
    Diabetes; 2003 Sep 24; 52(9):2315-20. PubMed ID: 12941771
    [Abstract] [Full Text] [Related]

  • 3. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme.
    Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ.
    J Mol Biol; 2010 Jan 15; 395(2):430-43. PubMed ID: 19896952
    [Abstract] [Full Text] [Related]

  • 4. Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
    Shen Y, Joachimiak A, Rosner MR, Tang WJ.
    Nature; 2006 Oct 19; 443(7113):870-4. PubMed ID: 17051221
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of Insulin-Degrading Enzyme Does Not Increase Islet Amyloid Deposition in Vitro.
    Hogan MF, Meier DT, Zraika S, Templin AT, Mellati M, Hull RL, Leissring MA, Kahn SE.
    Endocrinology; 2016 Sep 19; 157(9):3462-8. PubMed ID: 27404391
    [Abstract] [Full Text] [Related]

  • 6. Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones.
    Maianti JP, McFedries A, Foda ZH, Kleiner RE, Du XQ, Leissring MA, Tang WJ, Charron MJ, Seeliger MA, Saghatelian A, Liu DR.
    Nature; 2014 Jul 03; 511(7507):94-8. PubMed ID: 24847884
    [Abstract] [Full Text] [Related]

  • 7. Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.
    Durham TB, Toth JL, Klimkowski VJ, Cao JX, Siesky AM, Alexander-Chacko J, Wu GY, Dixon JT, McGee JE, Wang Y, Guo SY, Cavitt RN, Schindler J, Thibodeaux SJ, Calvert NA, Coghlan MJ, Sindelar DK, Christe M, Kiselyov VV, Michael MD, Sloop KW.
    J Biol Chem; 2015 Aug 14; 290(33):20044-59. PubMed ID: 26085101
    [Abstract] [Full Text] [Related]

  • 8. The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme.
    Bellia F, Grasso G.
    J Mass Spectrom; 2014 Apr 14; 49(4):274-9. PubMed ID: 24719342
    [Abstract] [Full Text] [Related]

  • 9. Nitric oxide inhibits insulin-degrading enzyme activity and function through S-nitrosylation.
    Cordes CM, Bennett RG, Siford GL, Hamel FG.
    Biochem Pharmacol; 2009 Mar 15; 77(6):1064-73. PubMed ID: 19154729
    [Abstract] [Full Text] [Related]

  • 10. Targeting Insulin-Degrading Enzyme to Treat Type 2 Diabetes Mellitus.
    Tang WJ.
    Trends Endocrinol Metab; 2016 Jan 15; 27(1):24-34. PubMed ID: 26651592
    [Abstract] [Full Text] [Related]

  • 11. Insulin inhibition of the proteasome is dependent on degradation of insulin by insulin-degrading enzyme.
    Bennett RG, Fawcett J, Kruer MC, Duckworth WC, Hamel FG.
    J Endocrinol; 2003 Jun 15; 177(3):399-405. PubMed ID: 12773120
    [Abstract] [Full Text] [Related]

  • 12. Insulin acts intracellularly on proteasomes through insulin-degrading enzyme.
    Duckworth WC, Bennett RG, Hamel FG.
    Biochem Biophys Res Commun; 1998 Mar 17; 244(2):390-4. PubMed ID: 9514933
    [Abstract] [Full Text] [Related]

  • 13. Redox regulation of insulin degradation by insulin-degrading enzyme.
    Cordes CM, Bennett RG, Siford GL, Hamel FG.
    PLoS One; 2011 Mar 23; 6(3):e18138. PubMed ID: 21448434
    [Abstract] [Full Text] [Related]

  • 14. Degradation of relaxin family peptides by insulin-degrading enzyme.
    Bennett RG, Heimann DG, Hamel FG.
    Ann N Y Acad Sci; 2009 Apr 23; 1160():38-41. PubMed ID: 19416156
    [Abstract] [Full Text] [Related]

  • 15. Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver.
    Ogawa W, Shii K, Yonezawa K, Baba S, Yokono K.
    J Biol Chem; 1992 Jan 15; 267(2):1310-6. PubMed ID: 1730651
    [Abstract] [Full Text] [Related]

  • 16. Non-covalent interaction of ubiquitin with insulin-degrading enzyme.
    Saric T, Müller D, Seitz HJ, Pavelic K.
    Mol Cell Endocrinol; 2003 Jun 30; 204(1-2):11-20. PubMed ID: 12850277
    [Abstract] [Full Text] [Related]

  • 17. Geniposide protects pancreatic INS-1E β cells from hIAPP-induced cell damage: potential involvement of insulin degrading-enzyme.
    Zhang Y, Yin F, Liu J, Wang Y.
    Cell Biol Int; 2015 Apr 30; 39(4):373-8. PubMed ID: 25319222
    [Abstract] [Full Text] [Related]

  • 18. Insulin-degrading enzyme: structure-function relationship and its possible roles in health and disease.
    Fernández-Gamba A, Leal MC, Morelli L, Castaño EM.
    Curr Pharm Des; 2009 Apr 30; 15(31):3644-55. PubMed ID: 19925417
    [Abstract] [Full Text] [Related]

  • 19. Characterization of insulin degrading enzyme and other amyloid-β degrading proteases in human serum: a role in Alzheimer's disease?
    Liu Z, Zhu H, Fang GG, Walsh K, Mwamburi M, Wolozin B, Abdul-Hay SO, Ikezu T, Leissring MA, Qiu WQ.
    J Alzheimers Dis; 2012 Apr 30; 29(2):329-40. PubMed ID: 22232014
    [Abstract] [Full Text] [Related]

  • 20. Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme.
    Adamek RN, Suire CN, Stokes RW, Brizuela MK, Cohen SM, Leissring MA.
    ChemMedChem; 2021 Jun 07; 16(11):1775-1787. PubMed ID: 33686743
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 14.