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Journal Abstract Search

165 related items for PubMed ID: 10991972

  • 1. Limited distribution of new quinolone antibacterial agents into brain caused by multiple efflux transporters at the blood-brain barrier.
    Tamai I, Yamashita J, Kido Y, Ohnari A, Sai Y, Shima Y, Naruhashi K, Koizumi S, Tsuji A.
    J Pharmacol Exp Ther; 2000 Oct; 295(1):146-52. PubMed ID: 10991972
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  • 3. Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein.
    Naruhashi K, Tamai I, Inoue N, Muraoka H, Sai Y, Suzuki N, Tsuji A.
    J Pharm Pharmacol; 2001 May; 53(5):699-709. PubMed ID: 11370709
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  • 4. Secretory mechanisms of grepafloxacin and levofloxacin in the human intestinal cell line caco-2.
    Yamaguchi H, Yano I, Hashimoto Y, Inui KI.
    J Pharmacol Exp Ther; 2000 Oct; 295(1):360-6. PubMed ID: 10992002
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  • 5. Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo.
    Yamaguchi H, Yano I, Saito H, Inui K.
    J Pharmacol Exp Ther; 2002 Mar; 300(3):1063-9. PubMed ID: 11861816
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  • 7. Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.
    Yu XY, Lin SG, Chen X, Zhou ZW, Liang J, Duan W, Chowbay B, Wen JY, Chan E, Cao J, Li CG, Zhou SF.
    Curr Drug Metab; 2007 May; 8(4):365-78. PubMed ID: 17504224
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  • 9. The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice.
    Zhou L, Schmidt K, Nelson FR, Zelesky V, Troutman MD, Feng B.
    Drug Metab Dispos; 2009 May; 37(5):946-55. PubMed ID: 19225039
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  • 12. Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation.
    Roberts LM, Black DS, Raman C, Woodford K, Zhou M, Haggerty JE, Yan AT, Cwirla SE, Grindstaff KK.
    Neuroscience; 2008 Aug 13; 155(2):423-38. PubMed ID: 18619525
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  • 13. Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate.
    Kodaira H, Kusuhara H, Fujita T, Ushiki J, Fuse E, Sugiyama Y.
    J Pharmacol Exp Ther; 2011 Dec 13; 339(3):935-44. PubMed ID: 21934030
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  • 15. In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin.
    de Lange EC, Marchand S, van den Berg D, van der Sandt IC, de Boer AG, Delon A, Bouquet S, Couet W.
    Eur J Pharm Sci; 2000 Dec 13; 12(2):85-93. PubMed ID: 11102735
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  • 16. Distribution characteristics of levofloxacin and grepafloxacin in rat kidney.
    Ito T, Yano I, Masuda S, Hashimoto Y, Inui K.
    Pharm Res; 1999 Apr 13; 16(4):534-9. PubMed ID: 10227708
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  • 17. Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays.
    Baltes S, Fedrowitz M, Tortós CL, Potschka H, Löscher W.
    J Pharmacol Exp Ther; 2007 Jan 13; 320(1):331-43. PubMed ID: 17043155
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  • 18. Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier.
    Robillard KR, Hoque T, Bendayan R.
    J Pharmacol Exp Ther; 2012 Jan 13; 340(1):96-108. PubMed ID: 21990609
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  • 19. Multidrug resistance-associated protein 1 functions as an efflux pump of xenobiotics in the skin.
    Li Q, Kato Y, Sai Y, Imai T, Tsuji A.
    Pharm Res; 2005 Jun 13; 22(6):842-6. PubMed ID: 15948026
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  • 20. Fluoroquinolone efflux mediated by ABC transporters.
    Alvarez AI, Pérez M, Prieto JG, Molina AJ, Real R, Merino G.
    J Pharm Sci; 2008 Sep 13; 97(9):3483-93. PubMed ID: 18200507
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