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185 related items for PubMed ID: 10995035

  • 1. Significance of the Grb2 and son of sevenless (Sos) proteins in human bladder cancer cell lines.
    Watanabe T, Shinohara N, Moriya K, Sazawa A, Kobayashi Y, Ogiso Y, Takiguchi M, Yasuda J, Koyanagi T, Kuzumaki N, Hashimoto A.
    IUBMB Life; 2000 Apr; 49(4):317-20. PubMed ID: 10995035
    [Abstract] [Full Text] [Related]

  • 2. Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2.
    Janes PW, Daly RJ, deFazio A, Sutherland RL.
    Oncogene; 1994 Dec; 9(12):3601-8. PubMed ID: 7970720
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of the Grb2 gene in human breast cancer cell lines.
    Daly RJ, Binder MD, Sutherland RL.
    Oncogene; 1994 Sep; 9(9):2723-7. PubMed ID: 8058337
    [Abstract] [Full Text] [Related]

  • 4. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
    Hu Y, Bowtell DD.
    Oncogene; 1996 May 02; 12(9):1865-72. PubMed ID: 8649846
    [Abstract] [Full Text] [Related]

  • 5. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
    Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA.
    Nature; 1993 May 06; 363(6424):45-51. PubMed ID: 8479536
    [Abstract] [Full Text] [Related]

  • 6. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.
    Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J.
    Nature; 1993 May 06; 363(6424):85-8. PubMed ID: 8479541
    [Abstract] [Full Text] [Related]

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  • 8. Ha-ras induction of the invasive phenotype results in up-regulation of epidermal growth factor receptors and altered responsiveness to epidermal growth factor in human papillary transitional cell carcinoma cells.
    Theodorescu D, Cornil I, Sheehan C, Man MS, Kerbel RS.
    Cancer Res; 1991 Aug 15; 51(16):4486-91. PubMed ID: 1868471
    [Abstract] [Full Text] [Related]

  • 9. p21Ras activation by the guanine nucleotide exchange factor Sos, requires the Sos/Grb2 interaction and a second ligand-dependent signal involving the Sos N-terminus.
    Byrne JL, Paterson HF, Marshall CJ.
    Oncogene; 1996 Nov 21; 13(10):2055-65. PubMed ID: 8950972
    [Abstract] [Full Text] [Related]

  • 10. The Grb2 binding domain of mSos1 is not required for downstream signal transduction.
    Wang W, Fisher EM, Jia Q, Dunn JM, Porfiri E, Downward J, Egan SE.
    Nat Genet; 1995 Jul 21; 10(3):294-300. PubMed ID: 7670467
    [Abstract] [Full Text] [Related]

  • 11. Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells.
    Rubio I, Rennert K, Wittig U, Beer K, Dürst M, Stang SL, Stone J, Wetzker R.
    Biochem J; 2006 Sep 01; 398(2):243-56. PubMed ID: 16709153
    [Abstract] [Full Text] [Related]

  • 12. Growth inhibition of breast cancer cells by Grb2 downregulation is correlated with inactivation of mitogen-activated protein kinase in EGFR, but not in ErbB2, cells.
    Tari AM, Hung MC, Li K, Lopez-Berestein G.
    Oncogene; 1999 Feb 11; 18(6):1325-32. PubMed ID: 10022814
    [Abstract] [Full Text] [Related]

  • 13. Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling.
    Zhang T, Ma J, Cao X.
    Biochem J; 2003 Dec 01; 376(Pt 2):457-64. PubMed ID: 14498832
    [Abstract] [Full Text] [Related]

  • 14. Insulin-induced dissociation of Sos from Grb2 does not contribute to the down regulation of Ras activation.
    Corbalan-Garcia S, Degenhardt KR, Bar-Sagi D.
    Oncogene; 1996 Mar 07; 12(5):1063-8. PubMed ID: 8649797
    [Abstract] [Full Text] [Related]

  • 15. The gene structure of the human growth factor bound protein GRB2.
    Bochmann H, Gehrisch S, Jaross W.
    Genomics; 1999 Mar 01; 56(2):203-7. PubMed ID: 10051406
    [Abstract] [Full Text] [Related]

  • 16. Overexpression of epidermal growth factor receptor in urothelium elicits urothelial hyperplasia and promotes bladder tumor growth.
    Cheng J, Huang H, Zhang ZT, Shapiro E, Pellicer A, Sun TT, Wu XR.
    Cancer Res; 2002 Jul 15; 62(14):4157-63. PubMed ID: 12124355
    [Abstract] [Full Text] [Related]

  • 17. Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling.
    Najib S, Sánchez-Margalet V.
    J Cell Biochem; 2002 Jul 15; 86(1):99-106. PubMed ID: 12112020
    [Abstract] [Full Text] [Related]

  • 18. VEGF receptor expression and signaling in human bladder tumors.
    Wu W, Shu X, Hovsepyan H, Mosteller RD, Broek D.
    Oncogene; 2003 May 29; 22(22):3361-70. PubMed ID: 12776187
    [Abstract] [Full Text] [Related]

  • 19. A novel crosstalk mechanism between nuclear receptor-mediated and growth factor/Ras-mediated pathways through PNRC-Grb2 interaction.
    Zhou D, Chen B, Ye JJ, Chen S.
    Oncogene; 2004 Jul 08; 23(31):5394-404. PubMed ID: 15122321
    [Abstract] [Full Text] [Related]

  • 20. Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.
    Boerner JL, Danielsen AJ, Lovejoy CA, Wang Z, Juneja SC, Faupel-Badger JM, Darce JR, Maihle NJ.
    Oncogene; 2003 Oct 02; 22(43):6679-89. PubMed ID: 14555981
    [Abstract] [Full Text] [Related]

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