These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Novel, potent, and selective phosphodiesterase 5 inhibitors: synthesis and biological activities of a series of 4-aryl-1-isoquinolinone derivatives. Ukita T, Nakamura Y, Kubo A, Yamamoto Y, Moritani Y, Saruta K, Higashijima T, Kotera J, Takagi M, Kikkawa K, Omori K. J Med Chem; 2001 Jun 21; 44(13):2204-18. PubMed ID: 11405657 [Abstract] [Full Text] [Related]
5. Phosphodiesterase 5 and effects of sildenafil on cerebral arteries of man and guinea pig. Kruuse C, Khurana TS, Rybalkin SD, Birk S, Engel U, Edvinsson L, Olesen J. Eur J Pharmacol; 2005 Oct 03; 521(1-3):105-14. PubMed ID: 16182282 [Abstract] [Full Text] [Related]
6. Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships. Ko WC, Shih CM, Lai YH, Chen JH, Huang HL. Biochem Pharmacol; 2004 Nov 15; 68(10):2087-94. PubMed ID: 15476679 [Abstract] [Full Text] [Related]
10. Pharmacological profile of T-1032, a novel specific phosphodiesterase type 5 inhibitor, in isolated rat aorta and rabbit corpus cavernosum. Takagi M, Mochida H, Noto T, Yano K, Inoue H, Ikeo T, Kikkawa K. Eur J Pharmacol; 2001 Jan 05; 411(1-2):161-168. PubMed ID: 11137871 [Abstract] [Full Text] [Related]
15. The role of phosphodiesterase isoforms 2, 5, and 9 in the regulation of NO-dependent and NO-independent cGMP production in the rat cervical spinal cord. de Vente J, Markerink-van Ittersum M, Vles JS. J Chem Neuroanat; 2006 Jun 05; 31(4):275-303. PubMed ID: 16621445 [Abstract] [Full Text] [Related]
17. Role of cyclic AMP- and cyclic GMP-phosphodiesterases in the control of cyclic nucleotide levels and smooth muscle tone in rat isolated aorta. A study with selective inhibitors. Schoeffter P, Lugnier C, Demesy-Waeldele F, Stoclet JC. Biochem Pharmacol; 1987 Nov 15; 36(22):3965-72. PubMed ID: 2825708 [Abstract] [Full Text] [Related]
19. Angiotensin II increases phosphodiesterase 5A expression in vascular smooth muscle cells: a mechanism by which angiotensin II antagonizes cGMP signaling. Kim D, Aizawa T, Wei H, Pi X, Rybalkin SD, Berk BC, Yan C. J Mol Cell Cardiol; 2005 Jan 15; 38(1):175-84. PubMed ID: 15623434 [Abstract] [Full Text] [Related]