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276 related items for PubMed ID: 11021749

  • 1. Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis.
    Kitamura K, Minami Y, Yamamoto K, Akao Y, Kiyoi H, Saito H, Naoe T.
    Leukemia; 2000 Oct; 14(10):1743-50. PubMed ID: 11021749
    [Abstract] [Full Text] [Related]

  • 2. Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia.
    Cai X, Shen YL, Zhu Q, Jia PM, Yu Y, Zhou L, Huang Y, Zhang JW, Xiong SM, Chen SJ, Wang ZY, Chen Z, Chen GQ.
    Leukemia; 2000 Feb; 14(2):262-70. PubMed ID: 10673743
    [Abstract] [Full Text] [Related]

  • 3. Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner.
    Wang ZG, Rivi R, Delva L, König A, Scheinberg DA, Gambacorti-Passerini C, Gabrilove JL, Warrell RP, Pandolfi PP.
    Blood; 1998 Sep 01; 92(5):1497-504. PubMed ID: 9716575
    [Abstract] [Full Text] [Related]

  • 4. In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins.
    Chen GQ, Zhu J, Shi XG, Ni JH, Zhong HJ, Si GY, Jin XL, Tang W, Li XS, Xong SM, Shen ZX, Sun GL, Ma J, Zhang P, Zhang TD, Gazin C, Naoe T, Chen SJ, Wang ZY, Chen Z.
    Blood; 1996 Aug 01; 88(3):1052-61. PubMed ID: 8704214
    [Abstract] [Full Text] [Related]

  • 5. Arsenic trioxide induces apoptosis in leukemia/lymphoma cell lines via the CD95/CD95L system.
    Zhu J, Okumura H, Ohtake S, Nakamura S, Nakao S.
    Oncol Rep; 2003 Aug 01; 10(3):705-9. PubMed ID: 12684647
    [Abstract] [Full Text] [Related]

  • 6. In acute promyelocytic leukemia NB4 cells, the synthetic retinoid CD437 induces contemporaneously apoptosis, a caspase-3-mediated degradation of PML/RARalpha protein and the PML retargeting on PML-nuclear bodies.
    Giannì M, de Thé H.
    Leukemia; 1999 May 01; 13(5):739-49. PubMed ID: 10374879
    [Abstract] [Full Text] [Related]

  • 7. A novel differentiation-inducing therapy for acute promyelocytic leukemia with a combination of arsenic trioxide and GM-CSF.
    Muto A, Kizaki M, Kawamura C, Matsushita H, Fukuchi Y, Umezawa A, Yamada T, Hata J, Hozumi N, Yamato K, Ito M, Ueyama Y, Ikeda Y.
    Leukemia; 2001 Aug 01; 15(8):1176-84. PubMed ID: 11480559
    [Abstract] [Full Text] [Related]

  • 8. Phenylarsine oxide (PAO) more intensely induces apoptosis in acute promyelocytic leukemia and As2O3-resistant APL cell lines than As2O3 by activating the mitochondrial pathway.
    Sahara N, Takeshita A, Kobayashi M, Shigeno K, Nakamura S, Shinjo K, Naito K, Maekawa M, Horii T, Ohnishi K, Kitamura K, Naoe T, Hayash H, Ohno R.
    Leuk Lymphoma; 2004 May 01; 45(5):987-95. PubMed ID: 15291359
    [Abstract] [Full Text] [Related]

  • 9. Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations.
    Zhu XH, Shen YL, Jing YK, Cai X, Jia PM, Huang Y, Tang W, Shi GY, Sun YP, Dai J, Wang ZY, Chen SJ, Zhang TD, Waxman S, Chen Z, Chen GQ.
    J Natl Cancer Inst; 1999 May 05; 91(9):772-8. PubMed ID: 10328107
    [Abstract] [Full Text] [Related]

  • 10. Arsenic trioxide induces apoptosis in HTLV-I infected T-cell lines and fresh adult T-cell leukemia cells through CD95 or tumor necrosis factor alpha receptor independent caspase activation.
    Ishitsuka K, Ikeda R, Utsunomiya A, Uozumi K, Hanada S, Suzuki S, Takeuchi S, Takatsuka Y, Takeshita T, Ohno N, Arima T.
    Leuk Lymphoma; 2002 May 05; 43(5):1107-14. PubMed ID: 12148893
    [Abstract] [Full Text] [Related]

  • 11. Arsenic trioxide (As2O3)-induced apoptosis and differentiation in retinoic acid-resistant acute promyelocytic leukemia model in hGM-CSF-producing transgenic SCID mice.
    Kinjo K, Kizaki M, Muto A, Fukuchi Y, Umezawa A, Yamato K, Nishihara T, Hata J, Ito M, Ueyama Y, Ikeda Y.
    Leukemia; 2000 Mar 05; 14(3):431-8. PubMed ID: 10720138
    [Abstract] [Full Text] [Related]

  • 12. Combined arsenic and retinoic acid treatment enhances differentiation and apoptosis in arsenic-resistant NB4 cells.
    Giannì M, Koken MH, Chelbi-Alix MK, Benoit G, Lanotte M, Chen Z, de Thé H.
    Blood; 1998 Jun 01; 91(11):4300-10. PubMed ID: 9596679
    [Abstract] [Full Text] [Related]

  • 13. Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells.
    Shao W, Fanelli M, Ferrara FF, Riccioni R, Rosenauer A, Davison K, Lamph WW, Waxman S, Pelicci PG, Lo Coco F, Avvisati G, Testa U, Peschle C, Gambacorti-Passerini C, Nervi C, Miller WH.
    J Natl Cancer Inst; 1998 Jan 21; 90(2):124-33. PubMed ID: 9450572
    [Abstract] [Full Text] [Related]

  • 14. PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.
    Sternsdorf T, Puccetti E, Jensen K, Hoelzer D, Will H, Ottmann OG, Ruthardt M.
    Mol Cell Biol; 1999 Jul 21; 19(7):5170-8. PubMed ID: 10373566
    [Abstract] [Full Text] [Related]

  • 15. Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system.
    Dai J, Weinberg RS, Waxman S, Jing Y.
    Blood; 1999 Jan 01; 93(1):268-77. PubMed ID: 9864170
    [Abstract] [Full Text] [Related]

  • 16. Role of GSTP1-1 in mediating the effect of As2O3 in the Acute Promyelocytic Leukemia cell line NB4.
    Bernardini S, Nuccetelli M, Noguera NI, Bellincampi L, Lunghi P, Bonati A, Mann K, Miller WH, Federici G, Lo Coco F.
    Ann Hematol; 2006 Oct 01; 85(10):681-7. PubMed ID: 16733740
    [Abstract] [Full Text] [Related]

  • 17. Arsenic trioxide therapy for relapsed acute promyelocytic leukemia: an useful salvage therapy.
    Huan SY, Yang CH, Chen YC.
    Leuk Lymphoma; 2000 Jul 01; 38(3-4):283-93. PubMed ID: 10830735
    [Abstract] [Full Text] [Related]

  • 18. The effects of arsenic trioxide (As2O3) on human megakaryocytic leukemia cell lines. With a comparison of its effects on other cell lineages.
    Alemany M, Levin J.
    Leuk Lymphoma; 2000 Jun 01; 38(1-2):153-63. PubMed ID: 10811458
    [Abstract] [Full Text] [Related]

  • 19. MicroRNAs contribute to promyelocyte apoptosis in As2O3-treated APL cells.
    Liang H, Li X, Wang L, Yu S, Xu Z, Gu Y, Pan Z, Li T, Hu M, Cui H, Liu X, Zhang Y, Xu C, Guo R, Lu Y, Yang B, Shan H.
    Cell Physiol Biochem; 2013 Jun 01; 32(6):1818-29. PubMed ID: 24356076
    [Abstract] [Full Text] [Related]

  • 20. Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells.
    Chen GQ, Shi XG, Tang W, Xiong SM, Zhu J, Cai X, Han ZG, Ni JH, Shi GY, Jia PM, Liu MM, He KL, Niu C, Ma J, Zhang P, Zhang TD, Paul P, Naoe T, Kitamura K, Miller W, Waxman S, Wang ZY, de The H, Chen SJ, Chen Z.
    Blood; 1997 May 01; 89(9):3345-53. PubMed ID: 9129041
    [Abstract] [Full Text] [Related]

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