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135 related items for PubMed ID: 11023830

  • 1. Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea.
    Mackintosh CA, Pegg AE.
    Biochem J; 2000 Oct 15; 351 Pt 2(Pt 2):439-47. PubMed ID: 11023830
    [Abstract] [Full Text] [Related]

  • 2. Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells.
    Stefanelli C, Pignatti C, Tantini B, Fattori M, Stanic I, Mackintosh CA, Flamigni F, Guarnieri C, Caldarera CM, Pegg AE.
    Biochem J; 2001 Apr 01; 355(Pt 1):199-206. PubMed ID: 11256964
    [Abstract] [Full Text] [Related]

  • 3. Partial deletion of both the spermine synthase gene and the Pex gene in the X-linked hypophosphatemic, gyro (Gy) mouse.
    Meyer RA, Henley CM, Meyer MH, Morgan PL, McDonald AG, Mills C, Price DK.
    Genomics; 1998 Mar 15; 48(3):289-95. PubMed ID: 9545633
    [Abstract] [Full Text] [Related]

  • 4. Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene.
    Lorenz B, Francis F, Gempel K, Böddrich A, Josten M, Schmahl W, Schmidt J, Lehrach H, Meitinger T, Strom TM.
    Hum Mol Genet; 1998 Mar 15; 7(3):541-7. PubMed ID: 9467015
    [Abstract] [Full Text] [Related]

  • 5. Skin fibroblasts from spermine synthase-deficient hemizygous gyro male (Gy/Y) mice overproduce spermidine and exhibit increased resistance to oxidative stress but decreased resistance to UV irradiation.
    Nilsson J, Gritli-Linde A, Heby O.
    Biochem J; 2000 Dec 01; 352 Pt 2(Pt 2):381-7. PubMed ID: 11085931
    [Abstract] [Full Text] [Related]

  • 6. Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis.
    Lopatin AN, Shantz LM, Mackintosh CA, Nichols CG, Pegg AE.
    J Mol Cell Cardiol; 2000 Nov 01; 32(11):2007-24. PubMed ID: 11040105
    [Abstract] [Full Text] [Related]

  • 7. Effect of spermine synthase on the sensitivity of cells to anti-tumour agents.
    Ikeguchi Y, Mackintosh CA, McCloskey DE, Pegg AE.
    Biochem J; 2003 Aug 01; 373(Pt 3):885-92. PubMed ID: 12737625
    [Abstract] [Full Text] [Related]

  • 8. Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine.
    Wang X, Levic S, Gratton MA, Doyle KJ, Yamoah EN, Pegg AE.
    J Biol Chem; 2009 Jan 09; 284(2):930-7. PubMed ID: 19001365
    [Abstract] [Full Text] [Related]

  • 9. Spermine synthesis is required for normal viability, growth, and fertility in the mouse.
    Wang X, Ikeguchi Y, McCloskey DE, Nelson P, Pegg AE.
    J Biol Chem; 2004 Dec 03; 279(49):51370-5. PubMed ID: 15459188
    [Abstract] [Full Text] [Related]

  • 10. (R,R)-1,12-Dimethylspermine can mitigate abnormal spermidine accumulation in Snyder-Robinson syndrome.
    Murray Stewart T, Khomutov M, Foley JR, Guo X, Holbert CE, Dunston TT, Schwartz CE, Gabrielson K, Khomutov A, Casero RA.
    J Biol Chem; 2020 Mar 06; 295(10):3247-3256. PubMed ID: 31996374
    [Abstract] [Full Text] [Related]

  • 11. Characterization of transgenic mice with widespread overexpression of spermine synthase.
    Ikeguchi Y, Wang X, McCloskey DE, Coleman CS, Nelson P, Hu G, Shantz LM, Pegg AE.
    Biochem J; 2004 Aug 01; 381(Pt 3):701-7. PubMed ID: 15104536
    [Abstract] [Full Text] [Related]

  • 12. Major increases in spermidine/spermine-N1-acetyltransferase activity by spermine analogues and their relationship to polyamine depletion and growth inhibition in L1210 cells.
    Libby PR, Henderson M, Bergeron RJ, Porter CW.
    Cancer Res; 1989 Nov 15; 49(22):6226-31. PubMed ID: 2804970
    [Abstract] [Full Text] [Related]

  • 13. Selective cellular depletion of mitochondrial DNA by the polyamine analog N1,N12-bis(ethyl)spermine and its relationship to polyamine structure and function.
    Vertino PM, Beerman TA, Kelly EJ, Bergeron RJ, Porter CW.
    Mol Pharmacol; 1991 Apr 15; 39(4):487-94. PubMed ID: 2017149
    [Abstract] [Full Text] [Related]

  • 14. Spermine synthase deficiency resulting in X-linked intellectual disability (Snyder-Robinson syndrome).
    Schwartz CE, Wang X, Stevenson RE, Pegg AE.
    Methods Mol Biol; 2011 Apr 15; 720():437-45. PubMed ID: 21318891
    [Abstract] [Full Text] [Related]

  • 15. Relative abilities of bis(ethyl) derivatives of putrescine, spermidine, and spermine to regulate polyamine biosynthesis and inhibit L1210 leukemia cell growth.
    Porter CW, McManis J, Casero RA, Bergeron RJ.
    Cancer Res; 1987 Jun 01; 47(11):2821-5. PubMed ID: 3567905
    [Abstract] [Full Text] [Related]

  • 16. Antitumor activity of N1,N11-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action.
    Porter CW, Bernacki RJ, Miller J, Bergeron RJ.
    Cancer Res; 1993 Feb 01; 53(3):581-6. PubMed ID: 8425191
    [Abstract] [Full Text] [Related]

  • 17. Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
    Cavanaugh PF, Pavelic ZP, Porter CW.
    Cancer Res; 1984 Sep 01; 44(9):3856-61. PubMed ID: 6430555
    [Abstract] [Full Text] [Related]

  • 18. Use of (Gyro) Gy and spermine synthase transgenic mice to study functions of spermine.
    Wang X, Pegg AE.
    Methods Mol Biol; 2011 Sep 01; 720():159-70. PubMed ID: 21318872
    [Abstract] [Full Text] [Related]

  • 19. Catabolism of polyamines.
    Seiler N.
    Amino Acids; 2004 Jun 01; 26(3):217-33. PubMed ID: 15221502
    [Abstract] [Full Text] [Related]

  • 20. Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine.
    Alhonen L, Pietilä M, Halmekytö M, Kramer DL, Jänne J, Porter CW.
    Mol Pharmacol; 1999 Apr 01; 55(4):693-8. PubMed ID: 10101027
    [Abstract] [Full Text] [Related]

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