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Journal Abstract Search

274 related items for PubMed ID: 11024027

  • 1. Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti protein.
    Oosterom J, Garner KM, den Dekker WK, Nijenhuis WA, Gispen WH, Burbach JP, Barsh GS, Adan RA.
    J Biol Chem; 2001 Jan 12; 276(2):931-6. PubMed ID: 11024027
    [Abstract] [Full Text] [Related]

  • 2. Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants.
    Haskell-Luevano C, Cone RD, Monck EK, Wan YP.
    Biochemistry; 2001 May 22; 40(20):6164-79. PubMed ID: 11352754
    [Abstract] [Full Text] [Related]

  • 3. Conformation of the core sequence in melanocortin peptides directs selectivity for the melanocortin MC3 and MC4 receptors.
    Oosterom J, Nijenhuis WA, Schaaper WM, Slootstra J, Meloen RH, Gispen WH, Burbach JP, Adan RA.
    J Biol Chem; 1999 Jun 11; 274(24):16853-60. PubMed ID: 10358030
    [Abstract] [Full Text] [Related]

  • 4. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A, Wang XS, Joseph CG, Xiang Z, Bauzo RM, Scott JW, Sorensen NB, Shaw AM, Millard WJ, Richards NG, Haskell-Luevano C.
    J Med Chem; 2004 Apr 22; 47(9):2194-207. PubMed ID: 15084118
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  • 6. Identification of domains directing specificity of coupling to G-proteins for the melanocortin MC3 and MC4 receptors.
    Kim CS, Lee SH, Kim RY, Kim BJ, Li SZ, Lee IH, Lee EJ, Lim SK, Bae YS, Lee W, Baik JH.
    J Biol Chem; 2002 Aug 30; 277(35):31310-7. PubMed ID: 12045190
    [Abstract] [Full Text] [Related]

  • 7. Chimeras of the agouti-related protein: insights into agonist and antagonist selectivity of melanocortin receptors.
    Jackson PJ, Yu B, Hunrichs B, Thompson DA, Chai B, Gantz I, Millhauser GL.
    Peptides; 2005 Oct 30; 26(10):1978-87. PubMed ID: 16009463
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  • 9. Molecular determination of agouti-related protein binding to human melanocortin-4 receptor.
    Yang Y, Chen M, Lai Y, Gantz I, Yagmurlu A, Georgeson KE, Harmon CM.
    Mol Pharmacol; 2003 Jul 30; 64(1):94-103. PubMed ID: 12815165
    [Abstract] [Full Text] [Related]

  • 10. Characterization of Agouti-related protein binding to melanocortin receptors.
    Yang YK, Thompson DA, Dickinson CJ, Wilken J, Barsh GS, Kent SB, Gantz I.
    Mol Endocrinol; 1999 Jan 30; 13(1):148-55. PubMed ID: 9892020
    [Abstract] [Full Text] [Related]

  • 11. Chimeric NDP-MSH and MTII melanocortin peptides with agouti-related protein (AGRP) Arg-Phe-Phe amino acids possess agonist melanocortin receptor activity.
    Joseph CG, Wilczynski A, Holder JR, Xiang Z, Bauzo RM, Scott JW, Haskell-Luevano C.
    Peptides; 2003 Dec 30; 24(12):1899-908. PubMed ID: 15127941
    [Abstract] [Full Text] [Related]

  • 12. Differential regulation of cAMP-mediated gene transcription and ligand selectivity by MC3R and MC4R melanocortin receptors.
    Lee EJ, Lee SH, Jung JW, Lee W, Kim BJ, Park KW, Lim SK, Yoon CJ, Baik JH.
    Eur J Biochem; 2001 Feb 30; 268(3):582-91. PubMed ID: 11168397
    [Abstract] [Full Text] [Related]

  • 13. Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist.
    Xiang Z, Litherland SA, Sorensen NB, Proneth B, Wood MS, Shaw AM, Millard WJ, Haskell-Luevano C.
    Biochemistry; 2006 Jun 13; 45(23):7277-88. PubMed ID: 16752916
    [Abstract] [Full Text] [Related]

  • 14. Biased signaling initiated by agouti-related peptide through human melanocortin-3 and -4 receptors.
    Yang Z, Tao YX.
    Biochim Biophys Acta; 2016 Sep 13; 1862(9):1485-94. PubMed ID: 27208795
    [Abstract] [Full Text] [Related]

  • 15. Minimization of MC1R selectivity by modification of the core structure of alpha-MSH-ND.
    Lim S, Li S, Lee C, Yoon C, Baik J, Lee W.
    Chem Biol; 2001 Sep 13; 8(9):857-70. PubMed ID: 11564554
    [Abstract] [Full Text] [Related]

  • 16. Inverse agonist activity of agouti and agouti-related protein.
    Chai BX, Neubig RR, Millhauser GL, Thompson DA, Jackson PJ, Barsh GS, Dickinson CJ, Li JY, Lai YM, Gantz I.
    Peptides; 2003 Apr 13; 24(4):603-9. PubMed ID: 12860205
    [Abstract] [Full Text] [Related]

  • 17. Novel agouti-related-protein-based melanocortin-1 receptor antagonist.
    Thirumoorthy R, Holder JR, Bauzo RM, Richards NG, Edison AS, Haskell-Luevano C.
    J Med Chem; 2001 Nov 22; 44(24):4114-24. PubMed ID: 11708914
    [Abstract] [Full Text] [Related]

  • 18. Elongation studies of the human agouti-related protein (AGRP) core decapeptide (Yc[CRFFNAFC]Y) results in antagonism at the mouse melanocortin-3 receptor.
    Joseph CG, Bauzo RM, Xiang Z, Shaw AM, Millard WJ, Haskell-Luevano C.
    Peptides; 2003 Feb 22; 24(2):263-70. PubMed ID: 12668211
    [Abstract] [Full Text] [Related]

  • 19. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
    Hruby VJ, Lu D, Sharma SD, Castrucci AL, Kesterson RA, al-Obeidi FA, Hadley ME, Cone RD.
    J Med Chem; 1995 Sep 01; 38(18):3454-61. PubMed ID: 7658432
    [Abstract] [Full Text] [Related]

  • 20. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA, Doufexis M, Kapas S, Chhajlani V.
    Biochem Biophys Res Commun; 2001 Mar 09; 281(4):851-7. PubMed ID: 11237737
    [Abstract] [Full Text] [Related]

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