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Journal Abstract Search


1379 related items for PubMed ID: 11032030

  • 1. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.
    Iwamoto T, Senga T, Naito Y, Matsuda S, Miyake Y, Yoshimura A, Hamaguchi M.
    Oncogene; 2000 Sep 28; 19(41):4795-801. PubMed ID: 11032030
    [Abstract] [Full Text] [Related]

  • 2. A new protein containing an SH2 domain that inhibits JAK kinases.
    Endo TA, Masuhara M, Yokouchi M, Suzuki R, Sakamoto H, Mitsui K, Matsumoto A, Tanimura S, Ohtsubo M, Misawa H, Miyazaki T, Leonor N, Taniguchi T, Fujita T, Kanakura Y, Komiya S, Yoshimura A.
    Nature; 1997 Jun 26; 387(6636):921-4. PubMed ID: 9202126
    [Abstract] [Full Text] [Related]

  • 3. Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity.
    Zhang Y, Turkson J, Carter-Su C, Smithgall T, Levitzki A, Kraker A, Krolewski JJ, Medveczky P, Jove R.
    J Biol Chem; 2000 Aug 11; 275(32):24935-44. PubMed ID: 10823829
    [Abstract] [Full Text] [Related]

  • 4. A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons.
    Sakamoto H, Yasukawa H, Masuhara M, Tanimura S, Sasaki A, Yuge K, Ohtsubo M, Ohtsuka A, Fujita T, Ohta T, Furukawa Y, Iwase S, Yamada H, Yoshimura A.
    Blood; 1998 Sep 01; 92(5):1668-76. PubMed ID: 9716595
    [Abstract] [Full Text] [Related]

  • 5. CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells.
    Suzuki R, Sakamoto H, Yasukawa H, Masuhara M, Wakioka T, Sasaki A, Yuge K, Komiya S, Inoue A, Yoshimura A.
    Oncogene; 1998 Oct 29; 17(17):2271-8. PubMed ID: 9811457
    [Abstract] [Full Text] [Related]

  • 6. Involvement of JAK/STAT (Janus kinase/signal transducer and activator of transcription) in the thyrotropin signaling pathway.
    Park ES, Kim H, Suh JM, Park SJ, You SH, Chung HK, Lee KW, Kwon OY, Cho BY, Kim YK, Ro HK, Chung J, Shong M.
    Mol Endocrinol; 2000 May 29; 14(5):662-70. PubMed ID: 10809230
    [Abstract] [Full Text] [Related]

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  • 8. Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo.
    Hamanaka I, Saito Y, Yasukawa H, Kishimoto I, Kuwahara K, Miyamoto Y, Harada M, Ogawa E, Kajiyama N, Takahashi N, Izumi T, Kawakami R, Masuda I, Yoshimura A, Nakao K.
    Circ Res; 2001 Apr 13; 88(7):727-32. PubMed ID: 11304496
    [Abstract] [Full Text] [Related]

  • 9. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM, Heinrich PC.
    Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [Abstract] [Full Text] [Related]

  • 10. Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1.
    Chang YJ, Holtzman MJ, Chen CC.
    Mol Pharmacol; 2004 Mar 01; 65(3):589-98. PubMed ID: 14978237
    [Abstract] [Full Text] [Related]

  • 11. Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells.
    Nishimura R, Moriyama K, Yasukawa K, Mundy GR, Yoneda T.
    J Bone Miner Res; 1998 May 01; 13(5):777-85. PubMed ID: 9610741
    [Abstract] [Full Text] [Related]

  • 12. Thyrotropin induces SOCS-1 (suppressor of cytokine signaling-1) and SOCS-3 in FRTL-5 thyroid cells.
    Park ES, Kim H, Suh JM, Park SJ, Kwon OY, Kim YK, Ro HK, Cho BY, Chung J, Shong M.
    Mol Endocrinol; 2000 Mar 01; 14(3):440-8. PubMed ID: 10707961
    [Abstract] [Full Text] [Related]

  • 13. Suppressor of cytokine signaling 1/JAB and suppressor of cytokine signaling 3/cytokine-inducible SH2 containing protein 3 negatively regulate the signal transducers and activators of transcription signaling pathway in normal human epidermal keratinocytes.
    Yamasaki K, Hanakawa Y, Tokumaru S, Shirakata Y, Sayama K, Hanada T, Yoshimura A, Hashimoto K.
    J Invest Dermatol; 2003 Apr 01; 120(4):571-80. PubMed ID: 12648219
    [Abstract] [Full Text] [Related]

  • 14. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.
    Smit LS, Meyer DJ, Billestrup N, Norstedt G, Schwartz J, Carter-Su C.
    Mol Endocrinol; 1996 May 01; 10(5):519-33. PubMed ID: 8732683
    [Abstract] [Full Text] [Related]

  • 15. Prolactin-induced expression of cytokine-inducible SH2 signaling inhibitors in human hematopoietic progenitors.
    Cwikel S, Silvian-Drachsler I, Prolov L, Hooghe-Peters EL, Merchav S.
    Exp Hematol; 2001 Aug 01; 29(8):937-42. PubMed ID: 11495699
    [Abstract] [Full Text] [Related]

  • 16. Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia.
    Kim HY, Park EJ, Joe EH, Jou I.
    J Immunol; 2003 Dec 01; 171(11):6072-9. PubMed ID: 14634121
    [Abstract] [Full Text] [Related]

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  • 18. Epigenetic modification of SOCS-1 differentially regulates STAT3 activation in response to interleukin-6 receptor and epidermal growth factor receptor signaling through JAK and/or MEK in head and neck squamous cell carcinomas.
    Lee TL, Yeh J, Van Waes C, Chen Z.
    Mol Cancer Ther; 2006 Jan 01; 5(1):8-19. PubMed ID: 16432158
    [Abstract] [Full Text] [Related]

  • 19. A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.
    Hanada T, Yoshida T, Kinjyo I, Minoguchi S, Yasukawa H, Kato S, Mimata H, Nomura Y, Seki Y, Kubo M, Yoshimura A.
    J Biol Chem; 2001 Nov 02; 276(44):40746-54. PubMed ID: 11522790
    [Abstract] [Full Text] [Related]

  • 20. Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.
    Radaeva S, Jaruga B, Kim WH, Heller T, Liang TJ, Gao B.
    Biochem J; 2004 Apr 01; 379(Pt 1):199-208. PubMed ID: 14690454
    [Abstract] [Full Text] [Related]


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