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2. Kinetic characterization of channel impaired mutants of tryptophan synthase. Anderson KS, Kim AY, Quillen JM, Sayers E, Yang XJ, Miles EW. J Biol Chem; 1995 Dec 15; 270(50):29936-44. PubMed ID: 8530393 [Abstract] [Full Text] [Related]
6. Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the beta-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium. Brzović PS, Kayastha AM, Miles EW, Dunn MF. Biochemistry; 1992 Feb 04; 31(4):1180-90. PubMed ID: 1346502 [Abstract] [Full Text] [Related]
7. Serine modulates substrate channeling in tryptophan synthase. A novel intersubunit triggering mechanism. Anderson KS, Miles EW, Johnson KA. J Biol Chem; 1991 May 05; 266(13):8020-33. PubMed ID: 1902468 [Abstract] [Full Text] [Related]
11. Ligand-mediated changes in the tryptophan synthase indole tunnel probed by nile red fluorescence with wild type, mutant, and chemically modified enzymes. Ruvinov SB, Yang XJ, Parris KD, Banik U, Ahmed SA, Miles EW, Sackett DL. J Biol Chem; 1995 Mar 17; 270(11):6357-69. PubMed ID: 7890774 [Abstract] [Full Text] [Related]
12. Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme. Weyand M, Schlichting I, Herde P, Marabotti A, Mozzarelli A. J Biol Chem; 2002 Mar 22; 277(12):10653-60. PubMed ID: 11756454 [Abstract] [Full Text] [Related]
13. Tryptophan synthase: a multienzyme complex with an intramolecular tunnel. Miles EW. Chem Rec; 2001 Mar 22; 1(2):140-51. PubMed ID: 11893063 [Abstract] [Full Text] [Related]
15. The reaction of indole with the aminoacrylate intermediate of Salmonella typhimurium tryptophan synthase: observation of a primary kinetic isotope effect with 3-[(2)H]indole. Cash MT, Miles EW, Phillips RS. Arch Biochem Biophys; 2004 Dec 15; 432(2):233-43. PubMed ID: 15542062 [Abstract] [Full Text] [Related]