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Journal Abstract Search

151 related items for PubMed ID: 11040039

  • 1. Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
    Balzarini J, Aquaro S, Knispel T, Rampazzo C, Bianchi V, Perno CF, De Clercq E, Meier C.
    Mol Pharmacol; 2000 Nov; 58(5):928-35. PubMed ID: 11040039
    [Abstract] [Full Text] [Related]

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  • 3. cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine monophosphate (cycloSal-d4TMP): synthesis and antiviral evaluation of a new d4TMP delivery system.
    Meier C, Lorey M, De Clercq E, Balzarini J.
    J Med Chem; 1998 Apr 23; 41(9):1417-27. PubMed ID: 9554875
    [Abstract] [Full Text] [Related]

  • 4. Comparative study of bis(benzyl)phosphate triesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) and cyclosal-d4TMP--hydrolysis, mechanistic insights and anti-HIV activity.
    Meier C, Muus U, Renze J, Naesens L, De Clercq E, Balzarini J.
    Antivir Chem Chemother; 2002 Mar 23; 13(2):101-14. PubMed ID: 12238528
    [Abstract] [Full Text] [Related]

  • 5. Bis-cycloSal-d4T-monophosphates: drugs that deliver two molecules of bioactive nucleotides.
    Ducho C, Görbig U, Jessel S, Gisch N, Balzarini J, Meier C.
    J Med Chem; 2007 Mar 22; 50(6):1335-46. PubMed ID: 17328534
    [Abstract] [Full Text] [Related]

  • 6. Aryl-substituted and benzo-annulated cyc/osal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate--correlation of structure, hydrolysis properties and anti-HIV activity.
    Ducho C, Balzarini J, Naesens L, De Clercq E, Meier C.
    Antivir Chem Chemother; 2002 Mar 22; 13(2):129-41. PubMed ID: 12238530
    [Abstract] [Full Text] [Related]

  • 7. Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
    Saboulard D, Naesens L, Cahard D, Salgado A, Pathirana R, Velazquez S, McGuigan C, De Clercq E, Balzarini J.
    Mol Pharmacol; 1999 Oct 22; 56(4):693-704. PubMed ID: 10496951
    [Abstract] [Full Text] [Related]

  • 8. Stereoselective synthesis and antiviral activity of methyl-substituted cycloSal-pronucleotides.
    Rios Morales EH, Balzarini J, Meier C.
    J Med Chem; 2012 Aug 23; 55(16):7245-52. PubMed ID: 22827702
    [Abstract] [Full Text] [Related]

  • 9. Enzymatically activated cycloSal-d4T-monophosphates: The third generation of cycloSal-pronucleotides.
    Gisch N, Balzarini J, Meier C.
    J Med Chem; 2007 Apr 05; 50(7):1658-67. PubMed ID: 17335187
    [Abstract] [Full Text] [Related]

  • 10. 5-(1-Acetoxyvinyl)-cycloSaligenyl-2',3'-dideoxy-2',3'- didehydrothymidine monophosphates, a second type of new, enzymatically activated cycloSaligenyl pronucleotides.
    Gisch N, Pertenbreiter F, Balzarini J, Meier C.
    J Med Chem; 2008 Dec 25; 51(24):8115-23. PubMed ID: 19053827
    [Abstract] [Full Text] [Related]

  • 11. Doubly loaded cycloSaligenyl-pronucleotides - 5,5'-Bis-(cycloSaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine monophosphates).
    Gisch N, Balzarini J, Meier C.
    J Med Chem; 2009 Jun 11; 52(11):3464-73. PubMed ID: 19438207
    [Abstract] [Full Text] [Related]

  • 12. d4TMP delivery from 7-substituted cycloSal-d4TMPs.
    Meier C, Renze JT, Balzarini J, De Clercq E.
    Nucleosides Nucleotides Nucleic Acids; 2003 Jun 11; 22(5-8):825-7. PubMed ID: 14565288
    [Abstract] [Full Text] [Related]

  • 13. Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates.
    Meyer PR, Matsuura SE, Schinazi RF, So AG, Scott WA.
    Antimicrob Agents Chemother; 2000 Dec 11; 44(12):3465-72. PubMed ID: 11083661
    [Abstract] [Full Text] [Related]

  • 14. 5-diacetoxymethyl-cycloSal-d4TMP - A prototype of enzymatically activated cycloSal-pronucleotides.
    Gisch N, Balzarini J, Meier C.
    Nucleosides Nucleotides Nucleic Acids; 2007 Dec 11; 26(6-7):861-4. PubMed ID: 18066914
    [Abstract] [Full Text] [Related]

  • 15. Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
    Paintsil E, Dutschman GE, Hu R, Grill SP, Lam W, Baba M, Tanaka H, Cheng YC.
    Antimicrob Agents Chemother; 2007 Nov 11; 51(11):3870-9. PubMed ID: 17724147
    [Abstract] [Full Text] [Related]

  • 16. Benzyl-functionalized cycloSal-d4T monophosphates.
    Renze J, Plath M, Ducho C, Balzarini J, De Clercq E, Meier C.
    Nucleosides Nucleotides Nucleic Acids; 2001 Nov 11; 20(4-7):931-4. PubMed ID: 11563147
    [Abstract] [Full Text] [Related]

  • 17. cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.
    Meiera C, Renzea J, Ducho C, Balzarini J.
    Curr Top Med Chem; 2002 Oct 11; 2(10):1111-21. PubMed ID: 12173970
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, and in vitro enzymatic and antiviral evaluation of d4T polyphosphate derivatives as chain terminators.
    Yang S, Pannecouque C, Herdewijn P.
    Chem Biodivers; 2012 Oct 11; 9(10):2186-94. PubMed ID: 23081918
    [Abstract] [Full Text] [Related]

  • 19. Effects of cycloSal-d4TMP derivatives in H9 cells with induced AZT resistance phenotype.
    Gröschel B, Meier C, Zehner R, Cinatl J, Doerr HW, Cinatl J.
    Nucleosides Nucleotides; 1999 Oct 11; 18(4-5):933-6. PubMed ID: 10432712
    [Abstract] [Full Text] [Related]

  • 20. Lack of evidence for in vivo transformation of zidovudine triphosphate to stavudine triphosphate in human immunodeficiency virus-infected patients.
    Meléndez M, Blanco R, Delgado W, García R, Santana J, García H, Rosario O, Rodríguez JF.
    Antimicrob Agents Chemother; 2006 Mar 11; 50(3):835-40. PubMed ID: 16495240
    [Abstract] [Full Text] [Related]

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