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Journal Abstract Search

402 related items for PubMed ID: 11069675

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  • 2. Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis.
    Larsen MH, Vilchèze C, Kremer L, Besra GS, Parsons L, Salfinger M, Heifets L, Hazbon MH, Alland D, Sacchettini JC, Jacobs WR.
    Mol Microbiol; 2002 Oct; 46(2):453-66. PubMed ID: 12406221
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  • 3. Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.
    Kremer L, Dover LG, Morbidoni HR, Vilchèze C, Maughan WN, Baulard A, Tu SC, Honoré N, Deretic V, Sacchettini JC, Locht C, Jacobs WR, Besra GS.
    J Biol Chem; 2003 Jun 06; 278(23):20547-54. PubMed ID: 12654922
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  • 4. Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB.
    Schaeffer ML, Agnihotri G, Volker C, Kallender H, Brennan PJ, Lonsdale JT.
    J Biol Chem; 2001 Dec 14; 276(50):47029-37. PubMed ID: 11600501
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  • 5. The role of KasA and KasB in the biosynthesis of meromycolic acids and isoniazid resistance in Mycobacterium tuberculosis.
    Slayden RA, Barry CE.
    Tuberculosis (Edinb); 2002 Dec 14; 82(4-5):149-60. PubMed ID: 12464486
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  • 6. Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.
    Mdluli K, Slayden RA, Zhu Y, Ramaswamy S, Pan X, Mead D, Crane DD, Musser JM, Barry CE.
    Science; 1998 Jun 05; 280(5369):1607-10. PubMed ID: 9616124
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  • 8. Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis.
    Vilchèze C, Morbidoni HR, Weisbrod TR, Iwamoto H, Kuo M, Sacchettini JC, Jacobs WR.
    J Bacteriol; 2000 Jul 05; 182(14):4059-67. PubMed ID: 10869086
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  • 9. The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance.
    Banerjee A, Sugantino M, Sacchettini JC, Jacobs WR.
    Microbiology (Reading); 1998 Oct 05; 144 ( Pt 10)():2697-2704. PubMed ID: 9802011
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  • 14. Biological evaluation of potent triclosan-derived inhibitors of the enoyl-acyl carrier protein reductase InhA in drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis.
    Stec J, Vilchèze C, Lun S, Perryman AL, Wang X, Freundlich JS, Bishai W, Jacobs WR, Kozikowski AP.
    ChemMedChem; 2014 Nov 05; 9(11):2528-37. PubMed ID: 25165007
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  • 15. Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid.
    Parikh SL, Xiao G, Tonge PJ.
    Biochemistry; 2000 Jul 04; 39(26):7645-50. PubMed ID: 10869170
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  • 16. Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis.
    Kremer L, Douglas JD, Baulard AR, Morehouse C, Guy MR, Alland D, Dover LG, Lakey JH, Jacobs WR, Brennan PJ, Minnikin DE, Besra GS.
    J Biol Chem; 2000 Jun 02; 275(22):16857-64. PubMed ID: 10747933
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  • 17. Protein-protein interactions within the Fatty Acid Synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability.
    Veyron-Churlet R, Guerrini O, Mourey L, Daffé M, Zerbib D.
    Mol Microbiol; 2004 Dec 02; 54(5):1161-72. PubMed ID: 15554959
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  • 18. Biphenyl-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme.
    Senior SJ, Illarionov PA, Gurcha SS, Campbell IB, Schaeffer ML, Minnikin DE, Besra GS.
    Bioorg Med Chem Lett; 2003 Nov 03; 13(21):3685-8. PubMed ID: 14552758
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  • 19. Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis.
    Kremer L, Dover LG, Carrère S, Nampoothiri KM, Lesjean S, Brown AK, Brennan PJ, Minnikin DE, Locht C, Besra GS.
    Biochem J; 2002 Jun 01; 364(Pt 2):423-30. PubMed ID: 12023885
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