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163 related items for PubMed ID: 11076527

  • 1. Spectroscopic detection of transient thiamin diphosphate-bound intermediates on benzoylformate decarboxylase.
    Sergienko EA, Wang J, Polovnikova L, Hasson MS, McLeish MJ, Kenyon GL, Jordan F.
    Biochemistry; 2000 Nov 14; 39(45):13862-9. PubMed ID: 11076527
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  • 2. Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.
    Chakraborty S, Nemeria NS, Balakrishnan A, Brandt GS, Kneen MM, Yep A, McLeish MJ, Kenyon GL, Petsko GA, Ringe D, Jordan F.
    Biochemistry; 2009 Feb 10; 48(5):981-94. PubMed ID: 19140682
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  • 4. Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate, benzoylformate, and pyruvate as substrates.
    Schütz A, Golbik R, König S, Hübner G, Tittmann K.
    Biochemistry; 2005 Apr 26; 44(16):6164-79. PubMed ID: 15835904
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  • 6. Structural and kinetic studies on native intermediates and an intermediate analogue in benzoylformate decarboxylase reveal a least motion mechanism with an unprecedented short-lived predecarboxylation intermediate.
    Bruning M, Berheide M, Meyer D, Golbik R, Bartunik H, Liese A, Tittmann K.
    Biochemistry; 2009 Apr 21; 48(15):3258-68. PubMed ID: 19182954
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  • 7. Mechanism of benzaldehyde lyase studied via thiamin diphosphate-bound intermediates and kinetic isotope effects.
    Chakraborty S, Nemeria N, Yep A, McLeish MJ, Kenyon GL, Jordan F.
    Biochemistry; 2008 Mar 25; 47(12):3800-9. PubMed ID: 18314961
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  • 8. Reactivity of intermediates in benzoylformate decarboxylase: avoiding the path to destruction.
    Hu Q, Kluger R.
    J Am Chem Soc; 2002 Dec 18; 124(50):14858-9. PubMed ID: 12475322
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  • 9. Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.
    Nemeria N, Baykal A, Joseph E, Zhang S, Yan Y, Furey W, Jordan F.
    Biochemistry; 2004 Jun 01; 43(21):6565-75. PubMed ID: 15157089
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  • 10. Accelerating unimolecular decarboxylation by preassociated acid catalysis in thiamin-derived intermediates: implicating Brønsted acids as carbanion traps in enzymes.
    Kluger R, Ikeda G, Hu Q, Cao P, Drewry J.
    J Am Chem Soc; 2006 Dec 13; 128(49):15856-64. PubMed ID: 17147398
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  • 11. The crystal structure of benzoylformate decarboxylase at 1.6 A resolution: diversity of catalytic residues in thiamin diphosphate-dependent enzymes.
    Hasson MS, Muscate A, McLeish MJ, Polovnikova LS, Gerlt JA, Kenyon GL, Petsko GA, Ringe D.
    Biochemistry; 1998 Jul 14; 37(28):9918-30. PubMed ID: 9665697
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  • 12. Radical phosphate transfer mechanism for the thiamin diphosphate- and FAD-dependent pyruvate oxidase from Lactobacillus plantarum. Kinetic coupling of intercofactor electron transfer with phosphate transfer to acetyl-thiamin diphosphate via a transient FAD semiquinone/hydroxyethyl-ThDP radical pair.
    Tittmann K, Wille G, Golbik R, Weidner A, Ghisla S, Hübner G.
    Biochemistry; 2005 Oct 11; 44(40):13291-303. PubMed ID: 16201755
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  • 16. Factors mediating activity, selectivity, and substrate specificity for the thiamin diphosphate-dependent enzymes benzaldehyde lyase and benzoylformate decarboxylase.
    Knoll M, Müller M, Pleiss J, Pohl M.
    Chembiochem; 2006 Dec 11; 7(12):1928-34. PubMed ID: 17051662
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  • 17. Dual catalytic apparatus of the thiamin diphosphate coenzyme: acid-base via the 1',4'-iminopyrimidine tautomer along with its electrophilic role.
    Jordan F, Nemeria NS, Zhang S, Yan Y, Arjunan P, Furey W.
    J Am Chem Soc; 2003 Oct 22; 125(42):12732-8. PubMed ID: 14558820
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  • 18. Kinetics and mechanism of benzoylformate decarboxylase using 13C and solvent deuterium isotope effects on benzoylformate and benzoylformate analogues.
    Weiss PM, Garcia GA, Kenyon GL, Cleland WW, Cook PF.
    Biochemistry; 1988 Mar 22; 27(6):2197-205. PubMed ID: 3378056
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  • 19. Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor.
    Brandt GS, Kneen MM, Chakraborty S, Baykal AT, Nemeria N, Yep A, Ruby DI, Petsko GA, Kenyon GL, McLeish MJ, Jordan F, Ringe D.
    Biochemistry; 2009 Apr 21; 48(15):3247-57. PubMed ID: 19320438
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  • 20. A bulky hydrophobic residue is not required to maintain the V-conformation of enzyme-bound thiamin diphosphate.
    Andrews FH, Tom AR, Gunderman PR, Novak WR, McLeish MJ.
    Biochemistry; 2013 May 07; 52(18):3028-30. PubMed ID: 23607689
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