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264 related items for PubMed ID: 11082464

  • 1. Anxiolytic-like effects of the prototypical metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine in rodents.
    Spooren WP, Vassout A, Neijt HC, Kuhn R, Gasparini F, Roux S, Porsolt RD, Gentsch C.
    J Pharmacol Exp Ther; 2000 Dec; 295(3):1267-75. PubMed ID: 11082464
    [Abstract] [Full Text] [Related]

  • 2. Anxiolytic-like activity of the mGluR5 antagonist MPEP: a comparison with diazepam and buspirone.
    Brodkin J, Busse C, Sukoff SJ, Varney MA.
    Pharmacol Biochem Behav; 2002 Sep; 73(2):359-66. PubMed ID: 12117590
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  • 4. Anxiolytic-like effects of group I metabotropic glutamate antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) in rats.
    Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E, Pilc A.
    Pol J Pharmacol; 2000 Sep; 52(6):463-6. PubMed ID: 11334240
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  • 5. Effects of the prototypical mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats.
    Spooren WP, Gasparini F, Bergmann R, Kuhn R.
    Eur J Pharmacol; 2000 Oct 20; 406(3):403-10. PubMed ID: 11040347
    [Abstract] [Full Text] [Related]

  • 6. Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist.
    Tatarczyńska E, Klodzińska A, Chojnacka-Wójcik E, Palucha A, Gasparini F, Kuhn R, Pilc A.
    Br J Pharmacol; 2001 Apr 20; 132(7):1423-30. PubMed ID: 11264235
    [Abstract] [Full Text] [Related]

  • 7. Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, D-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice.
    Mcgeehan AJ, Janak PH, Olive MF.
    Psychopharmacology (Berl); 2004 Jul 20; 174(2):266-73. PubMed ID: 14726993
    [Abstract] [Full Text] [Related]

  • 8. Anxiolytic-like effects of mGlu1 and mGlu5 receptor antagonists in rats.
    Pietraszek M, Sukhanov I, Maciejak P, Szyndler J, Gravius A, Wisłowska A, Płaźnik A, Bespalov AY, Danysz W.
    Eur J Pharmacol; 2005 May 02; 514(1):25-34. PubMed ID: 15878321
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  • 9. Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide].
    Satow A, Maehara S, Ise S, Hikichi H, Fukushima M, Suzuki G, Kimura T, Tanak T, Ito S, Kawamoto H, Ohta H.
    J Pharmacol Exp Ther; 2008 Aug 02; 326(2):577-86. PubMed ID: 18487514
    [Abstract] [Full Text] [Related]

  • 10. The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison.
    Ballard TM, Woolley ML, Prinssen E, Huwyler J, Porter R, Spooren W.
    Psychopharmacology (Berl); 2005 Apr 02; 179(1):218-29. PubMed ID: 15739074
    [Abstract] [Full Text] [Related]

  • 11. Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking.
    Tessari M, Pilla M, Andreoli M, Hutcheson DM, Heidbreder CA.
    Eur J Pharmacol; 2004 Sep 19; 499(1-2):121-33. PubMed ID: 15363959
    [Abstract] [Full Text] [Related]

  • 12. Behavioral effects of the selective blockade of metabotropic glutamate receptor subtype 5 in experimental hypoxia.
    Nadlewska A, Car H, Wiśniewska RJ, Wiśniewski K.
    Pol J Pharmacol; 2002 Sep 19; 54(2):95-102. PubMed ID: 12139116
    [Abstract] [Full Text] [Related]

  • 13. Effects of mGlu1 receptor blockade on anxiety-related behaviour in the rat lick suppression test.
    Steckler T, Lavreysen H, Oliveira AM, Aerts N, Van Craenendonck H, Prickaerts J, Megens A, Lesage AS.
    Psychopharmacology (Berl); 2005 Apr 19; 179(1):198-206. PubMed ID: 15821950
    [Abstract] [Full Text] [Related]

  • 14. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity.
    Porter RH, Jaeschke G, Spooren W, Ballard TM, Büttelmann B, Kolczewski S, Peters JU, Prinssen E, Wichmann J, Vieira E, Mühlemann A, Gatti S, Mutel V, Malherbe P.
    J Pharmacol Exp Ther; 2005 Nov 19; 315(2):711-21. PubMed ID: 16040814
    [Abstract] [Full Text] [Related]

  • 15. mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors.
    Movsesyan VA, O'Leary DM, Fan L, Bao W, Mullins PG, Knoblach SM, Faden AI.
    J Pharmacol Exp Ther; 2001 Jan 19; 296(1):41-7. PubMed ID: 11123360
    [Abstract] [Full Text] [Related]

  • 16. Effects of mGluR5 and mGluR1 antagonists on anxiety-like behavior and learning in developing rats.
    Mikulecká A, Mares P.
    Behav Brain Res; 2009 Dec 01; 204(1):133-9. PubMed ID: 19505510
    [Abstract] [Full Text] [Related]

  • 17. Effects of a metabotropic, mglu5, glutamate receptor antagonist on ethanol consumption by genetic drinking rats.
    McMillen BA, Crawford MS, Kulers CM, Williams HL.
    Alcohol Alcohol; 2005 Dec 01; 40(6):494-7. PubMed ID: 16186143
    [Abstract] [Full Text] [Related]

  • 18. The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety.
    Busse CS, Brodkin J, Tattersall D, Anderson JJ, Warren N, Tehrani L, Bristow LJ, Varney MA, Cosford ND.
    Neuropsychopharmacology; 2004 Nov 01; 29(11):1971-9. PubMed ID: 15305166
    [Abstract] [Full Text] [Related]

  • 19. Anxiolytic-like effects of the selective metabotropic glutamate receptor 5 antagonist MPEP after its intra-amygdaloid microinjection in three different non-conditioned rat models of anxiety.
    Pérez de la Mora M, Lara-García D, Jacobsen KX, Vázquez-García M, Crespo-Ramírez M, Flores-Gracia C, Escamilla-Marvan E, Fuxe K.
    Eur J Neurosci; 2006 May 01; 23(10):2749-59. PubMed ID: 16817878
    [Abstract] [Full Text] [Related]

  • 20. The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity.
    Henry SA, Lehmann-Masten V, Gasparini F, Geyer MA, Markou A.
    Neuropharmacology; 2002 Dec 01; 43(8):1199-209. PubMed ID: 12527469
    [Abstract] [Full Text] [Related]

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