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Journal Abstract Search

151 related items for PubMed ID: 11082700

  • 1. [Natural organic compounds that affect to microtubule functions: syntheses and structure-activity relationships of combretastatins, curacin A and their analogs as the colchicine-site ligands on tubulin].
    Iwasaki S, Shirai R.
    Yakugaku Zasshi; 2000 Oct; 120(10):875-89. PubMed ID: 11082700
    [Abstract] [Full Text] [Related]

  • 2. Natural organic compounds that affect to microtubule functions.
    Iwasaki S.
    Yakugaku Zasshi; 1998 Apr; 118(4):112-26. PubMed ID: 9564789
    [Abstract] [Full Text] [Related]

  • 3. Characterization of the interaction of the marine cyanobacterial natural product curacin A with the colchicine site of tubulin and initial structure-activity studies with analogues.
    Blokhin AV, Yoo HD, Geralds RS, Nagle DG, Gerwick WH, Hamel E.
    Mol Pharmacol; 1995 Sep; 48(3):523-31. PubMed ID: 7565634
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells.
    Verdier-Pinard P, Lai JY, Yoo HD, Yu J, Marquez B, Nagle DG, Nambu M, White JD, Falck JR, Gerwick WH, Day BW, Hamel E.
    Mol Pharmacol; 1998 Jan; 53(1):62-76. PubMed ID: 9443933
    [Abstract] [Full Text] [Related]

  • 5. Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin.
    Lin CM, Ho HH, Pettit GR, Hamel E.
    Biochemistry; 1989 Aug 22; 28(17):6984-91. PubMed ID: 2819042
    [Abstract] [Full Text] [Related]

  • 6. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM, Singh SB, Chu PS, Dempcy RO, Schmidt JM, Pettit GR, Hamel E.
    Mol Pharmacol; 1988 Aug 22; 34(2):200-8. PubMed ID: 3412321
    [Abstract] [Full Text] [Related]

  • 7. Development of combretastatins as potent tubulin polymerization inhibitors.
    Bukhari SNA, Kumar GB, Revankar HM, Qin HL.
    Bioorg Chem; 2017 Jun 22; 72():130-147. PubMed ID: 28460355
    [Abstract] [Full Text] [Related]

  • 8. Podophyllotoxin, steganacin and combretastatin: natural products that bind at the colchicine site of tubulin.
    Sackett DL.
    Pharmacol Ther; 1993 Aug 22; 59(2):163-228. PubMed ID: 8278462
    [Abstract] [Full Text] [Related]

  • 9. Chemistry and biology of curacin A.
    Wipf P, Reeves JT, Day BW.
    Curr Pharm Des; 2004 Aug 22; 10(12):1417-37. PubMed ID: 15134491
    [Abstract] [Full Text] [Related]

  • 10. Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum.
    Pettit GR, Singh SB, Niven ML, Hamel E, Schmidt JM.
    J Nat Prod; 1987 Aug 22; 50(1):119-31. PubMed ID: 3598594
    [Abstract] [Full Text] [Related]

  • 11. Isolation, structure, synthesis, and antimitotic properties of combretastatins B-3 and B-4 from Combretum caffrum.
    Pettit GR, Singh SB, Schmidt JM, Niven ML, Hamel E, Lin CM.
    J Nat Prod; 1988 Aug 22; 51(3):517-27. PubMed ID: 3404149
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of the cytotoxic mechanism mediated by baccatin III, the synthetic precursor of taxol.
    Pengsuparp T, Kingston DG, Neidigh KA, Cordell GA, Pezzuto JM.
    Chem Biol Interact; 1996 Aug 14; 101(2):103-14. PubMed ID: 8760392
    [Abstract] [Full Text] [Related]

  • 13. The interaction of the B-ring of colchicine with alpha-tubulin: a novel footprinting approach.
    Chaudhuri AR, Seetharamalu P, Schwarz PM, Hausheer FH, Ludueña RF.
    J Mol Biol; 2000 Nov 10; 303(5):679-92. PubMed ID: 11061968
    [Abstract] [Full Text] [Related]

  • 14. Discovery, synthesis, activities, structure-activity relationships, and clinical development of combretastatins and analogs as anticancer drugs. A comprehensive review.
    Singh SB.
    Nat Prod Rep; 2024 Feb 21; 41(2):298-322. PubMed ID: 38009216
    [Abstract] [Full Text] [Related]

  • 15. Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones.
    Ducki S, Mackenzie G, Greedy B, Armitage S, Chabert JF, Bennett E, Nettles J, Snyder JP, Lawrence NJ.
    Bioorg Med Chem; 2009 Nov 15; 17(22):7711-22. PubMed ID: 19837594
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and antimicrotubule activity of combretatropone derivatives.
    Janik ME, Bane SL.
    Bioorg Med Chem; 2002 Jun 15; 10(6):1895-903. PubMed ID: 11937347
    [Abstract] [Full Text] [Related]

  • 17. Biosynthesis of radiolabeled curacin A and its rapid and apparently irreversible binding to the colchicine site of tubulin.
    Verdier-Pinard P, Sitachitta N, Rossi JV, Sackett DL, Gerwick WH, Hamel E.
    Arch Biochem Biophys; 1999 Oct 01; 370(1):51-8. PubMed ID: 10496976
    [Abstract] [Full Text] [Related]

  • 18. A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach.
    Nguyen TL, McGrath C, Hermone AR, Burnett JC, Zaharevitz DW, Day BW, Wipf P, Hamel E, Gussio R.
    J Med Chem; 2005 Sep 22; 48(19):6107-16. PubMed ID: 16162011
    [Abstract] [Full Text] [Related]

  • 19. Microtubulin binding sites as target for developing anticancer agents.
    Islam MN, Iskander MN.
    Mini Rev Med Chem; 2004 Dec 22; 4(10):1077-104. PubMed ID: 15579115
    [Abstract] [Full Text] [Related]

  • 20. Anti-tubulin agents of natural origin: Targeting taxol, vinca, and colchicine binding domains.
    Naaz F, Haider MR, Shafi S, Yar MS.
    Eur J Med Chem; 2019 Jun 01; 171():310-331. PubMed ID: 30953881
    [Abstract] [Full Text] [Related]

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