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191 related items for PubMed ID: 11085933

  • 1. A single amino acid substitution (N297A) in the conserved NPXXY sequence of the human N-formyl peptide receptor results in inhibition of desensitization and endocytosis, and a dose-dependent shift in p42/44 mitogen-activated protein kinase activation and chemotaxis.
    Gripentrog JM, Jesaitis AJ, Miettinen HM.
    Biochem J; 2000 Dec 01; 352 Pt 2(Pt 2):399-407. PubMed ID: 11085933
    [Abstract] [Full Text] [Related]

  • 2. Differential roles of the NPXXY motif in formyl peptide receptor signaling.
    He R, Browning DD, Ye RD.
    J Immunol; 2001 Mar 15; 166(6):4099-105. PubMed ID: 11238659
    [Abstract] [Full Text] [Related]

  • 3. Experimental evidence for lack of homodimerization of the G protein-coupled human N-formyl peptide receptor.
    Gripentrog JM, Kantele KP, Jesaitis AJ, Miettinen HM.
    J Immunol; 2003 Sep 15; 171(6):3187-93. PubMed ID: 12960347
    [Abstract] [Full Text] [Related]

  • 4. Identification of putative sites of interaction between the human formyl peptide receptor and G protein.
    Miettinen HM, Gripentrog JM, Mason MM, Jesaitis AJ.
    J Biol Chem; 1999 Sep 24; 274(39):27934-42. PubMed ID: 10488141
    [Abstract] [Full Text] [Related]

  • 5. Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu.
    Mills JS, Miettinen HM, Cummings D, Jesaitis AJ.
    J Biol Chem; 2000 Dec 15; 275(50):39012-7. PubMed ID: 10960471
    [Abstract] [Full Text] [Related]

  • 6. The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met is a potent chemotactic agonist for mouse formyl peptide receptor.
    He R, Tan L, Browning DD, Wang JM, Ye RD.
    J Immunol; 2000 Oct 15; 165(8):4598-605. PubMed ID: 11035102
    [Abstract] [Full Text] [Related]

  • 7. Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on beta-arrestin translocation or receptor endocytosis.
    Gripentrog JM, Miettinen HM.
    Cell Signal; 2005 Oct 15; 17(10):1300-11. PubMed ID: 16038804
    [Abstract] [Full Text] [Related]

  • 8. Mutations of F110 and C126 of the formyl peptide receptor interfere with G-protein coupling and chemotaxis.
    Jones BE, Miettinen HM, Jesaitis AJ, Mills JS.
    J Periodontol; 2003 Apr 15; 74(4):475-84. PubMed ID: 12747452
    [Abstract] [Full Text] [Related]

  • 9. Chemotaxis of chinese hamster ovary cells expressing the human neutrophil formyl peptide receptor: role of signal transduction molecules and alpha5beta1 integrin.
    Miettinen HM, Gripentrog JM, Jesaitis AJ.
    J Cell Sci; 1998 Jul 30; 111 ( Pt 14)():1921-8. PubMed ID: 9645940
    [Abstract] [Full Text] [Related]

  • 10. Normal cell surface expression and selective loss of functions resulting from Phe110 to Ser and Cys126 to Trp substitutions in the formyl peptide receptor.
    Nanamori M, He R, Sang H, Ye RD.
    Immunol Invest; 2004 May 30; 33(2):193-212. PubMed ID: 15195697
    [Abstract] [Full Text] [Related]

  • 11. Identification of a ligand binding site in the human neutrophil formyl peptide receptor using a site-specific fluorescent photoaffinity label and mass spectrometry.
    Mills JS, Miettinen HM, Barnidge D, Vlases MJ, Wimer-Mackin S, Dratz EA, Sunner J, Jesaitis AJ.
    J Biol Chem; 1998 Apr 24; 273(17):10428-35. PubMed ID: 9553101
    [Abstract] [Full Text] [Related]

  • 12. Dexras1/AGS-1 inhibits signal transduction from the Gi-coupled formyl peptide receptor to Erk-1/2 MAP kinases.
    Graham TE, Prossnitz ER, Dorin RI.
    J Biol Chem; 2002 Mar 29; 277(13):10876-82. PubMed ID: 11751935
    [Abstract] [Full Text] [Related]

  • 13. Differential activation of formyl peptide receptor signaling by peptide ligands.
    Bae YS, Song JY, Kim Y, He R, Ye RD, Kwak JY, Suh PG, Ryu SH.
    Mol Pharmacol; 2003 Oct 29; 64(4):841-7. PubMed ID: 14500740
    [Abstract] [Full Text] [Related]

  • 14. The ligand binding site of the formyl peptide receptor maps in the transmembrane region.
    Miettinen HM, Mills JS, Gripentrog JM, Dratz EA, Granger BL, Jesaitis AJ.
    J Immunol; 1997 Oct 15; 159(8):4045-54. PubMed ID: 9378994
    [Abstract] [Full Text] [Related]

  • 15. Phosphorylation of the N-formyl peptide receptor is required for receptor internalization but not chemotaxis.
    Hsu MH, Chiang SC, Ye RD, Prossnitz ER.
    J Biol Chem; 1997 Nov 21; 272(47):29426-9. PubMed ID: 9367998
    [Abstract] [Full Text] [Related]

  • 16. Internalization of the human N-formyl peptide and C5a chemoattractant receptors occurs via clathrin-independent mechanisms.
    Gilbert TL, Bennett TA, Maestas DC, Cimino DF, Prossnitz ER.
    Biochemistry; 2001 Mar 27; 40(12):3467-75. PubMed ID: 11297412
    [Abstract] [Full Text] [Related]

  • 17. Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence.
    Bennett TA, Maestas DC, Prossnitz ER.
    J Biol Chem; 2000 Aug 11; 275(32):24590-4. PubMed ID: 10823817
    [Abstract] [Full Text] [Related]

  • 18. The thyrotropin receptor is not involved in the activation of p42/p44 mitogen-activated protein kinases by thyrotropin preparations in Chinese hamster ovary cells expressing the human thyrotropin receptor.
    Corrèze C, Blondeau JP, Pomerance M.
    Thyroid; 2000 Sep 11; 10(9):747-52. PubMed ID: 11041451
    [Abstract] [Full Text] [Related]

  • 19. Formyl peptide receptors are coupled to multiple mitogen-activated protein kinase cascades by distinct signal transduction pathways: role in activation of reduced nicotinamide adenine dinucleotide oxidase.
    Rane MJ, Carrithers SL, Arthur JM, Klein JB, McLeish KR.
    J Immunol; 1997 Nov 15; 159(10):5070-8. PubMed ID: 9366435
    [Abstract] [Full Text] [Related]

  • 20. The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR.
    Liang TS, Gao JL, Fatemi O, Lavigne M, Leto TL, Murphy PM.
    J Immunol; 2001 Dec 01; 167(11):6609-14. PubMed ID: 11714831
    [Abstract] [Full Text] [Related]

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