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162 related items for PubMed ID: 11093739

  • 1. Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome.
    Keitel V, Kartenbeck J, Nies AT, Spring H, Brom M, Keppler D.
    Hepatology; 2000 Dec; 32(6):1317-28. PubMed ID: 11093739
    [Abstract] [Full Text] [Related]

  • 2. A common Dubin-Johnson syndrome mutation impairs protein maturation and transport activity of MRP2 (ABCC2).
    Keitel V, Nies AT, Brom M, Hummel-Eisenbeiss J, Spring H, Keppler D.
    Am J Physiol Gastrointest Liver Physiol; 2003 Jan; 284(1):G165-74. PubMed ID: 12388192
    [Abstract] [Full Text] [Related]

  • 3. Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome.
    Hashimoto K, Uchiumi T, Konno T, Ebihara T, Nakamura T, Wada M, Sakisaka S, Maniwa F, Amachi T, Ueda K, Kuwano M.
    Hepatology; 2002 Nov; 36(5):1236-45. PubMed ID: 12395335
    [Abstract] [Full Text] [Related]

  • 4. Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome.
    Tsujii H, König J, Rost D, Stöckel B, Leuschner U, Keppler D.
    Gastroenterology; 1999 Sep; 117(3):653-60. PubMed ID: 10464142
    [Abstract] [Full Text] [Related]

  • 5. A new mutation of the ATP-binding cassette, sub-family C, member 2 (ABCC2) gene in a Japanese patient with Dubin-Johnson syndrome.
    Tate G, Li M, Suzuki T, Mitsuya T.
    Genes Genet Syst; 2002 Apr; 77(2):117-21. PubMed ID: 12087194
    [Abstract] [Full Text] [Related]

  • 6. Hepatic secretion of conjugated drugs and endogenous substances.
    Keppler D, König J.
    Semin Liver Dis; 2000 Apr; 20(3):265-72. PubMed ID: 11076395
    [Abstract] [Full Text] [Related]

  • 7. Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome.
    Mor-Cohen R, Zivelin A, Rosenberg N, Shani M, Muallem S, Seligsohn U.
    J Biol Chem; 2001 Oct 05; 276(40):36923-30. PubMed ID: 11477083
    [Abstract] [Full Text] [Related]

  • 8. Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome.
    Kartenbeck J, Leuschner U, Mayer R, Keppler D.
    Hepatology; 1996 May 05; 23(5):1061-6. PubMed ID: 8621134
    [Abstract] [Full Text] [Related]

  • 9. Dual hereditary jaundice: simultaneous occurrence of mutations causing Gilbert's and Dubin-Johnson syndrome.
    Cebecauerova D, Jirasek T, Budisova L, Mandys V, Volf V, Novotna Z, Subhanova I, Hrebicek M, Elleder M, Jirsa M.
    Gastroenterology; 2005 Jul 05; 129(1):315-20. PubMed ID: 16012956
    [Abstract] [Full Text] [Related]

  • 10. Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.
    König J, Nies AT, Cui Y, Leier I, Keppler D.
    Biochim Biophys Acta; 1999 Dec 06; 1461(2):377-94. PubMed ID: 10581368
    [Abstract] [Full Text] [Related]

  • 11. The roles of MRP2, MRP3, OATP1B1, and OATP1B3 in conjugated hyperbilirubinemia.
    Keppler D.
    Drug Metab Dispos; 2014 Apr 06; 42(4):561-5. PubMed ID: 24459177
    [Abstract] [Full Text] [Related]

  • 12. Mutation and functional analysis of ABCC2/multidrug resistance protein 2 in a Japanese patient with Dubin-Johnson syndrome.
    Uchiumi T, Tanamachi H, Kuchiwaki K, Kajita M, Matsumoto S, Yagi M, Kanki T, Kang D.
    Hepatol Res; 2013 May 06; 43(5):569-75. PubMed ID: 23045960
    [Abstract] [Full Text] [Related]

  • 13. Structural requirements for the apical sorting of human multidrug resistance protein 2 (ABCC2).
    Nies AT, König J, Cui Y, Brom M, Spring H, Keppler D.
    Eur J Biochem; 2002 Apr 06; 269(7):1866-76. PubMed ID: 11952788
    [Abstract] [Full Text] [Related]

  • 14. Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
    Jedlitschky G, Hoffmann U, Kroemer HK.
    Expert Opin Drug Metab Toxicol; 2006 Jun 06; 2(3):351-66. PubMed ID: 16863439
    [Abstract] [Full Text] [Related]

  • 15. A recurrent ABCC2 p.G693R mutation resulting in loss of function of MRP2 and hyperbilirubinemia in Dubin-Johnson syndrome in China.
    Wu L, Li Y, Song Y, Zhou D, Jia S, Xu A, Zhang W, You H, Jia J, Huang J, Ou X.
    Orphanet J Rare Dis; 2020 Mar 18; 15(1):74. PubMed ID: 32183854
    [Abstract] [Full Text] [Related]

  • 16. Identification of a novel 974C-->G nonsense mutation of the MRP2/ABCC2 gene in a patient with Dubin-Johnson syndrome and analysis of the effects of rifampicin and ursodeoxycholic acid on serum bilirubin and bile acids.
    Corpechot C, Ping C, Wendum D, Matsuda F, Barbu V, Poupon R.
    Am J Gastroenterol; 2006 Oct 18; 101(10):2427-32. PubMed ID: 16952291
    [Abstract] [Full Text] [Related]

  • 17. Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells.
    Cui Y, König J, Buchholz JK, Spring H, Leier I, Keppler D.
    Mol Pharmacol; 1999 May 18; 55(5):929-37. PubMed ID: 10220572
    [Abstract] [Full Text] [Related]

  • 18. The apical conjugate efflux pump ABCC2 (MRP2).
    Nies AT, Keppler D.
    Pflugers Arch; 2007 Feb 18; 453(5):643-59. PubMed ID: 16847695
    [Abstract] [Full Text] [Related]

  • 19. Dubin-Johnson syndrome.
    Nisa AU, Ahmad Z.
    J Coll Physicians Surg Pak; 2008 Mar 18; 18(3):188-9. PubMed ID: 18460254
    [Abstract] [Full Text] [Related]

  • 20. Novel mutations in the Dubin-Johnson syndrome gene ABCC2/MRP2 and associated biochemical changes.
    Devgun MS, El-Nujumi AM, O'Dowd GJ, Barbu V, Poupon R.
    Ann Clin Biochem; 2012 Nov 18; 49(Pt 6):609-12. PubMed ID: 23065530
    [Abstract] [Full Text] [Related]

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