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78 related items for PubMed ID: 11095102

  • 1. Role of tyrosine kinase signaling for beta-cell replication and survival.
    Welsh M, Annerén C, Lindholm C, Kriz V, Oberg-Welsh C.
    Ups J Med Sci; 2000; 105(2):7-15. PubMed ID: 11095102
    [Abstract] [Full Text] [Related]

  • 2. Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK.
    Annerén C, Welsh M.
    Mol Med; 2001 May; 7(5):301-10. PubMed ID: 11474576
    [Abstract] [Full Text] [Related]

  • 3. Dual role of the tyrosine kinase GTK and the adaptor protein SHB in beta-cell growth: enhanced beta-cell replication after 60% pancreatectomy and increased sensitivity to streptozotocin.
    Annerén C.
    J Endocrinol; 2002 Jan; 172(1):145-53. PubMed ID: 11786382
    [Abstract] [Full Text] [Related]

  • 4. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C, Welsh M.
    Mol Med; 2002 Nov; 8(11):705-13. PubMed ID: 12520087
    [Abstract] [Full Text] [Related]

  • 5. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N, Makeeva N, Welsh M.
    Mol Med; 2002 Nov; 8(11):695-704. PubMed ID: 12520086
    [Abstract] [Full Text] [Related]

  • 6. The FRK/RAK-SHB signaling cascade: a versatile signal-transduction pathway that regulates cell survival, differentiation and proliferation.
    Annerén C, Lindholm CK, Kriz V, Welsh M.
    Curr Mol Med; 2003 Jun; 3(4):313-24. PubMed ID: 12776987
    [Abstract] [Full Text] [Related]

  • 7. GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase.
    Annerén C, Reedquist KA, Bos JL, Welsh M.
    J Biol Chem; 2000 Sep 15; 275(37):29153-61. PubMed ID: 10878015
    [Abstract] [Full Text] [Related]

  • 8. Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.
    Welsh M, Christmansson L, Karlsson T, Sandler S, Welsh N.
    Mol Med; 1999 Mar 15; 5(3):169-80. PubMed ID: 10404514
    [Abstract] [Full Text] [Related]

  • 9. The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity.
    Welsh M, Welsh C, Ekman M, Dixelius J, Hägerkvist R, Annerén C, Akerblom B, Mahboobi S, Chandrasekharan S, Liu ET.
    Biochem J; 2004 Aug 15; 382(Pt 1):261-8. PubMed ID: 15186217
    [Abstract] [Full Text] [Related]

  • 10. Role of the Bsk/Iyk non-receptor tyrosine kinase for the control of growth and hormone production in RINm5F cells.
    Annerén C, Welsh M.
    Growth Factors; 2000 Aug 15; 17(4):233-47. PubMed ID: 10801074
    [Abstract] [Full Text] [Related]

  • 11. Shb is a ubiquitously expressed Src homology 2 protein.
    Welsh M, Mares J, Karlsson T, Lavergne C, Bréant B, Claesson-Welsh L.
    Oncogene; 1994 Jan 15; 9(1):19-27. PubMed ID: 8302579
    [Abstract] [Full Text] [Related]

  • 12. The Src homology 2 domain protein Shb transmits basic fibroblast growth factor- and nerve growth factor-dependent differentiation signals in PC12 cells.
    Karlsson T, Kullander K, Welsh M.
    Cell Growth Differ; 1998 Sep 15; 9(9):757-66. PubMed ID: 9751119
    [Abstract] [Full Text] [Related]

  • 13. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
    Cousin SP, Hügl SR, Myers MG, White MF, Reifel-Miller A, Rhodes CJ.
    Biochem J; 1999 Dec 15; 344 Pt 3(Pt 3):649-58. PubMed ID: 10585851
    [Abstract] [Full Text] [Related]

  • 14. Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.
    Welsh M, Claesson-Welsh L, Hallberg A, Welsh N, Betsholtz C, Arkhammar P, Nilsson T, Heldin CH, Berggren PO.
    Proc Natl Acad Sci U S A; 1990 Aug 15; 87(15):5807-11. PubMed ID: 2165603
    [Abstract] [Full Text] [Related]

  • 15. The role of the Src Homology-2 domain containing protein B (SHB) in β cells.
    Welsh M, Jamalpour M, Zang G, Åkerblom B.
    J Mol Endocrinol; 2016 Jan 15; 56(1):R21-31. PubMed ID: 26489764
    [Abstract] [Full Text] [Related]

  • 16. The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.
    Cross MJ, Lu L, Magnusson P, Nyqvist D, Holmqvist K, Welsh M, Claesson-Welsh L.
    Mol Biol Cell; 2002 Aug 15; 13(8):2881-93. PubMed ID: 12181353
    [Abstract] [Full Text] [Related]

  • 17. Tyrosine phosphorylation of Shc is not required for proliferation or viability signaling by granulocyte-macrophage colony-stimulating factor in hematopoietic cell lines.
    Durstin M, Inhorn RC, Griffin JD.
    J Immunol; 1996 Jul 15; 157(2):534-40. PubMed ID: 8752899
    [Abstract] [Full Text] [Related]

  • 18. Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.
    Conejo R, Lorenzo M.
    J Cell Physiol; 2001 Apr 15; 187(1):96-108. PubMed ID: 11241354
    [Abstract] [Full Text] [Related]

  • 19. Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes.
    Marzo N, Mora C, Fabregat ME, Martín J, Usac EF, Franco C, Barbacid M, Gomis R.
    Diabetologia; 2004 Apr 15; 47(4):686-94. PubMed ID: 15298346
    [Abstract] [Full Text] [Related]

  • 20. The LMP2A protein of Epstein-Barr virus regulates phosphorylation of ITSN1 and Shb adaptors by tyrosine kinases.
    Dergai O, Dergai M, Skrypkina I, Matskova L, Tsyba L, Gudkova D, Rynditch A.
    Cell Signal; 2013 Jan 15; 25(1):33-40. PubMed ID: 22975684
    [Abstract] [Full Text] [Related]

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