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196 related items for PubMed ID: 11113703

  • 1. Micronuclei and gene mutations in transgenic big Blue((R)) mouse and rat fibroblasts after exposure to the epoxide metabolites of 1, 3-butadiene.
    Erexson GL, Tindall KR.
    Mutat Res; 2000 Dec 20; 472(1-2):105-17. PubMed ID: 11113703
    [Abstract] [Full Text] [Related]

  • 2. Reduction of diepoxybutane-induced sister chromatid exchanges by glutathione peroxidase and erythrocytes in transgenic Big Blue mouse and rat fibroblasts.
    Erexson GL, Tindall KR.
    Mutat Res; 2000 Feb 14; 447(2):267-74. PubMed ID: 10751610
    [Abstract] [Full Text] [Related]

  • 3. Genetic effects of 1,3-butadiene and associated risk for heritable damage.
    Pacchierotti F, Adler ID, Anderson D, Brinkworth M, Demopoulos NA, Lähdetie J, Osterman-Golkar S, Peltonen K, Russo A, Tates A, Waters R.
    Mutat Res; 1998 Jan 16; 397(1):93-115. PubMed ID: 9463556
    [Abstract] [Full Text] [Related]

  • 4. Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure.
    Koivisto P, Kilpeläinen I, Rasanen I, Adler ID, Pacchierotti F, Peltonen K.
    Carcinogenesis; 1999 Jul 16; 20(7):1253-9. PubMed ID: 10383898
    [Abstract] [Full Text] [Related]

  • 5. Germ cell mutagenicity of three metabolites of 1,3-butadiene in the rat: induction of spermatid micronuclei by butadiene mono-, di-, and diolepoxides in vivo.
    Lähdetie J, Peltonen K, Sjöblom T.
    Environ Mol Mutagen; 1997 Jul 16; 29(3):230-9. PubMed ID: 9142165
    [Abstract] [Full Text] [Related]

  • 6. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
    Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF, Health Review Committee.
    Res Rep Health Eff Inst; 2009 Aug 16; (144):3-79. PubMed ID: 20017413
    [Abstract] [Full Text] [Related]

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  • 8. Mutational spectrum of 1,3-butadiene and metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane to assess mutagenic mechanisms.
    Recio L, Steen AM, Pluta LJ, Meyer KG, Saranko CJ.
    Chem Biol Interact; 2001 Jun 01; 135-136():325-41. PubMed ID: 11397399
    [Abstract] [Full Text] [Related]

  • 9. Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.
    Himmelstein MW, Turner MJ, Asgharian B, Bond JA.
    Carcinogenesis; 1994 Aug 01; 15(8):1479-86. PubMed ID: 8055623
    [Abstract] [Full Text] [Related]

  • 10. Epidemiological and mechanistic data suggest that 1,3-butadiene will not be carcinogenic to humans at exposures likely to be encountered in the environment or workplace.
    Bond JA, Recio L, Andjelkovich D.
    Carcinogenesis; 1995 Feb 01; 16(2):165-71. PubMed ID: 7859344
    [Abstract] [Full Text] [Related]

  • 11. Insights into the toxicokinetics and toxicodynamics of 1,3-butadiene.
    Bond JA, Medinsky MA.
    Chem Biol Interact; 2001 Jun 01; 135-136():599-614. PubMed ID: 11397415
    [Abstract] [Full Text] [Related]

  • 12. Physiologically based pharmacokinetic modeling of 1,3-butadiene, 1,2-epoxy-3-butene, and 1,2:3,4-diepoxybutane toxicokinetics in mice and rats.
    Sweeney LM, Schlosser PM, Medinsky MA, Bond JA.
    Carcinogenesis; 1997 Apr 01; 18(4):611-25. PubMed ID: 9111190
    [Abstract] [Full Text] [Related]

  • 13. 1,3-butadiene: cancer, mutations, and adducts. Part III: In vivo mutation of the endogenous hprt genes of mice and rats by 1,3-butadiene and its metabolites.
    Walker VE, Meng Q.
    Res Rep Health Eff Inst; 2000 Mar 01; (92):89-139; discussion 141-9. PubMed ID: 10925840
    [Abstract] [Full Text] [Related]

  • 14. Characterization of new transgenic Big Blue(R) mouse and rat primary fibroblast cell strains for use in molecular toxicology studies.
    Erexson GL, Watson DE, Tindall KR.
    Environ Mol Mutagen; 1999 Mar 01; 34(2-3):90-6. PubMed ID: 10529731
    [Abstract] [Full Text] [Related]

  • 15. Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice.
    Csanády GA, Guengerich FP, Bond JA.
    Carcinogenesis; 1992 Jul 01; 13(7):1143-53. PubMed ID: 1638680
    [Abstract] [Full Text] [Related]

  • 16. Determination of mutagenicity in tissues of transgenic mice following exposure to 1,3-butadiene and N-ethyl-N-nitrosourea.
    Recio L, Osterman-Golkar S, Csanády GA, Turner MJ, Myhr B, Moss O, Bond JA.
    Toxicol Appl Pharmacol; 1992 Nov 01; 117(1):58-64. PubMed ID: 1440614
    [Abstract] [Full Text] [Related]

  • 17. Mutations induced by 1,3-butadiene metabolites, butadiene diolepoxide, and 1,2,3,4-diepoxybutane at the Hprt locus in CHO-K1 cells.
    Lee DH, Kim TH, Lee SY, Kim HJ, Rhee SK, Yoon B, Pfeifer GP, Lee CS.
    Mol Cells; 2002 Dec 31; 14(3):411-9. PubMed ID: 12521305
    [Abstract] [Full Text] [Related]

  • 18. The butadiene metabolite, 1,2:3,4-diepoxybutane, induces micronuclei but is only weakly mutagenic at lacI in the Big Blue Rat2 lacI transgenic cell line.
    Saranko CJ, Recio L.
    Environ Mol Mutagen; 1998 Dec 31; 31(1):32-40. PubMed ID: 9464313
    [Abstract] [Full Text] [Related]

  • 19. A review of the genetic and related effects of 1,3-butadiene in rodents and humans.
    Jackson MA, Stack HF, Rice JM, Waters MD.
    Mutat Res; 2000 Oct 31; 463(3):181-213. PubMed ID: 11018742
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats.
    Filser JG, Hutzler C, Meischner V, Veereshwarayya V, Csanády GA.
    Chem Biol Interact; 2007 Mar 20; 166(1-3):93-103. PubMed ID: 16616907
    [Abstract] [Full Text] [Related]

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