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385 related items for PubMed ID: 11114166

  • 1. Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation.
    Kim JE, Chen J.
    Proc Natl Acad Sci U S A; 2000 Dec 19; 97(26):14340-5. PubMed ID: 11114166
    [Abstract] [Full Text] [Related]

  • 2. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1.
    Burnett PE, Barrow RK, Cohen NA, Snyder SH, Sabatini DM.
    Proc Natl Acad Sci U S A; 1998 Feb 17; 95(4):1432-7. PubMed ID: 9465032
    [Abstract] [Full Text] [Related]

  • 3. Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein.
    Peterson RT, Desai BN, Hardwick JS, Schreiber SL.
    Proc Natl Acad Sci U S A; 1999 Apr 13; 96(8):4438-42. PubMed ID: 10200280
    [Abstract] [Full Text] [Related]

  • 4. Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
    Lekmine F, Uddin S, Sassano A, Parmar S, Brachmann SM, Majchrzak B, Sonenberg N, Hay N, Fish EN, Platanias LC.
    J Biol Chem; 2003 Jul 25; 278(30):27772-80. PubMed ID: 12759354
    [Abstract] [Full Text] [Related]

  • 5. Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling.
    Sabatini DM, Barrow RK, Blackshaw S, Burnett PE, Lai MM, Field ME, Bahr BA, Kirsch J, Betz H, Snyder SH.
    Science; 1999 May 14; 284(5417):1161-4. PubMed ID: 10325225
    [Abstract] [Full Text] [Related]

  • 6. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism.
    Hara K, Yonezawa K, Weng QP, Kozlowski MT, Belham C, Avruch J.
    J Biol Chem; 1998 Jun 05; 273(23):14484-94. PubMed ID: 9603962
    [Abstract] [Full Text] [Related]

  • 7. Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation.
    Kumar V, Pandey P, Sabatini D, Kumar M, Majumder PK, Bharti A, Carmichael G, Kufe D, Kharbanda S.
    EMBO J; 2000 Mar 01; 19(5):1087-97. PubMed ID: 10698949
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1.
    El-Chaâr D, Gagnon A, Sorisky A.
    Int J Obes Relat Metab Disord; 2004 Feb 01; 28(2):191-8. PubMed ID: 14970836
    [Abstract] [Full Text] [Related]

  • 9. Regulation of eIF-4E BP1 phosphorylation by mTOR.
    Hara K, Yonezawa K, Kozlowski MT, Sugimoto T, Andrabi K, Weng QP, Kasuga M, Nishimoto I, Avruch J.
    J Biol Chem; 1997 Oct 17; 272(42):26457-63. PubMed ID: 9334222
    [Abstract] [Full Text] [Related]

  • 10. Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
    Wang X, Beugnet A, Murakami M, Yamanaka S, Proud CG.
    Mol Cell Biol; 2005 Apr 17; 25(7):2558-72. PubMed ID: 15767663
    [Abstract] [Full Text] [Related]

  • 11. Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.
    Pham PT, Heydrick SJ, Fox HL, Kimball SR, Jefferson LS, Lynch CJ.
    J Cell Biochem; 2000 Sep 07; 79(3):427-41. PubMed ID: 10972980
    [Abstract] [Full Text] [Related]

  • 12. RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.
    Villalonga P, Fernández de Mattos S, Ridley AJ.
    J Biol Chem; 2009 Dec 18; 284(51):35287-96. PubMed ID: 19850923
    [Abstract] [Full Text] [Related]

  • 13. p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation.
    Horton LE, Bushell M, Barth-Baus D, Tilleray VJ, Clemens MJ, Hensold JO.
    Oncogene; 2002 Aug 08; 21(34):5325-34. PubMed ID: 12149653
    [Abstract] [Full Text] [Related]

  • 14. Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps.
    Wang L, Wang X, Proud CG.
    Am J Physiol Heart Circ Physiol; 2000 Apr 08; 278(4):H1056-68. PubMed ID: 10749698
    [Abstract] [Full Text] [Related]

  • 15. Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.
    Beugnet A, Tee AR, Taylor PM, Proud CG.
    Biochem J; 2003 Jun 01; 372(Pt 2):555-66. PubMed ID: 12611592
    [Abstract] [Full Text] [Related]

  • 16. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.
    Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N.
    Genes Dev; 1998 Feb 15; 12(4):502-13. PubMed ID: 9472019
    [Abstract] [Full Text] [Related]

  • 17. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A, Usui I, Haruta T, Kawahara J, Uno T, Iwata M, Kobayashi M.
    Mol Cell Biol; 2001 Aug 15; 21(15):5050-62. PubMed ID: 11438661
    [Abstract] [Full Text] [Related]

  • 18. Identification of a conserved motif required for mTOR signaling.
    Schalm SS, Blenis J.
    Curr Biol; 2002 Apr 16; 12(8):632-9. PubMed ID: 11967149
    [Abstract] [Full Text] [Related]

  • 19. Regulation of cap-dependent translation by insulin-like growth factor-1 in neuronal cells.
    Quevedo C, Salinas M, Alcázar A.
    Biochem Biophys Res Commun; 2002 Mar 01; 291(3):560-6. PubMed ID: 11855825
    [Abstract] [Full Text] [Related]

  • 20. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.
    Gingras AC, Gygi SP, Raught B, Polakiewicz RD, Abraham RT, Hoekstra MF, Aebersold R, Sonenberg N.
    Genes Dev; 1999 Jun 01; 13(11):1422-37. PubMed ID: 10364159
    [Abstract] [Full Text] [Related]

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