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Journal Abstract Search


162 related items for PubMed ID: 11123991

  • 1. (2,2':6',2"-Terpyridine)platinum(II) complexes are irreversible inhibitors of Trypanosoma cruzi trypanothione reductase but not of human glutathione reductase.
    Bonse S, Richards JM, Ross SA, Lowe G, Krauth-Siegel RL.
    J Med Chem; 2000 Dec 14; 43(25):4812-21. PubMed ID: 11123991
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  • 3. Transfer of 4'-chloro-2,2':6',2"-terpyridine platinum(II) between human serum albumin, glutathione and other thiolate ligands. A possible selective natural transport mechanism for the delivery of platinum(II) drugs to tumour cells.
    Ross SA, Carr CA, Brïet JW, Lowe G.
    Anticancer Drug Des; 2000 Dec 14; 15(6):431-9. PubMed ID: 11716436
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  • 7. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
    Chan C, Yin H, Garforth J, McKie JH, Jaouhari R, Speers P, Douglas KT, Rock PJ, Yardley V, Croft SL, Fairlamb AH.
    J Med Chem; 1998 Jan 15; 41(2):148-56. PubMed ID: 9457238
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  • 8. Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds.
    Jockers-Scherübl MC, Schirmer RH, Krauth-Siegel RL.
    Eur J Biochem; 1989 Mar 15; 180(2):267-72. PubMed ID: 2647489
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  • 9. Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase.
    Duyzend MH, Clark CT, Simmons SL, Johnson WB, Larson AM, Leconte AM, Wills AW, Ginder-Vogel M, Wilhelm AK, Czechowicz JA, Alberg DG.
    J Enzyme Inhib Med Chem; 2012 Dec 15; 27(6):784-94. PubMed ID: 22085139
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  • 11. Structure-activity relationships in 2-aminodiphenylsulfides against trypanothione reductase from Trypanosoma cruzi.
    Girault S, Davioud-Charvet E, Salmon L, Berecibar A, Debreu MA, Sergheraert C.
    Bioorg Med Chem Lett; 1998 May 19; 8(10):1175-80. PubMed ID: 9871730
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  • 13. Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma.
    De Gasparo R, Brodbeck-Persch E, Bryson S, Hentzen NB, Kaiser M, Pai EF, Krauth-Siegel RL, Diederich F.
    ChemMedChem; 2018 May 08; 13(9):957-967. PubMed ID: 29624890
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  • 20. Synthesis and 2D-QSAR studies of neolignan-based diaryl-tetrahydrofuran and -furan analogues with remarkable activity against Trypanosoma cruzi and assessment of the trypanothione reductase activity.
    Hartmann AP, de Carvalho MR, Bernardes LSC, Moraes MH, de Melo EB, Lopes CD, Steindel M, da Silva JS, Carvalho I.
    Eur J Med Chem; 2017 Nov 10; 140():187-199. PubMed ID: 28926763
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