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282 related items for PubMed ID: 11145654

  • 1. Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors.
    Trobridge PA, Forbush KA, Levin SD.
    J Immunol; 2001 Jan 15; 166(2):809-18. PubMed ID: 11145654
    [Abstract] [Full Text] [Related]

  • 2. Activated p56lck directs maturation of both CD4 and CD8 single-positive thymocytes.
    Sohn SJ, Forbush KA, Pan XC, Perlmutter RM.
    J Immunol; 2001 Feb 15; 166(4):2209-17. PubMed ID: 11160274
    [Abstract] [Full Text] [Related]

  • 3. A CD8/Lck transgene is able to drive thymocyte differentiation.
    Fragoso RC, Pyarajan S, Irie HY, Burakoff SJ.
    J Immunol; 2006 Nov 01; 177(9):6007-17. PubMed ID: 17056525
    [Abstract] [Full Text] [Related]

  • 4. T-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages.
    Chiang YJ, Hodes RJ.
    Eur J Immunol; 2016 Oct 01; 46(10):2401-2408. PubMed ID: 27469439
    [Abstract] [Full Text] [Related]

  • 5. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
    Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A.
    J Exp Med; 1993 Nov 01; 178(5):1701-12. PubMed ID: 8228817
    [Abstract] [Full Text] [Related]

  • 6. The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck).
    Pingel S, Baker M, Turner M, Holmes N, Alexander DR.
    Eur J Immunol; 1999 Aug 01; 29(8):2376-84. PubMed ID: 10458749
    [Abstract] [Full Text] [Related]

  • 7. Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity.
    Shimizu C, Kawamoto H, Yamashita M, Kimura M, Kondou E, Kaneko Y, Okada S, Tokuhisa T, Yokoyama M, Taniguchi M, Katsura Y, Nakayama T.
    Int Immunol; 2001 Jan 01; 13(1):105-17. PubMed ID: 11133839
    [Abstract] [Full Text] [Related]

  • 8. Transgenic expression of RasGRP1 induces the maturation of double-negative thymocytes and enhances the production of CD8 single-positive thymocytes.
    Norment AM, Bogatzki LY, Klinger M, Ojala EW, Bevan MJ, Kay RJ.
    J Immunol; 2003 Feb 01; 170(3):1141-9. PubMed ID: 12538669
    [Abstract] [Full Text] [Related]

  • 9. ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
    Ashe JM, Wiest DL, Abe R, Singer A.
    J Exp Med; 1999 Apr 05; 189(7):1163-8. PubMed ID: 10190908
    [Abstract] [Full Text] [Related]

  • 10. Programmed death-1 (PD-1):PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes.
    Keir ME, Latchman YE, Freeman GJ, Sharpe AH.
    J Immunol; 2005 Dec 01; 175(11):7372-9. PubMed ID: 16301644
    [Abstract] [Full Text] [Related]

  • 11. Early growth response gene 3 regulates thymocyte proliferation during the transition from CD4-CD8- to CD4+CD8+.
    Xi H, Kersh GJ.
    J Immunol; 2004 Jan 15; 172(2):964-71. PubMed ID: 14707069
    [Abstract] [Full Text] [Related]

  • 12. Delayed thymocyte development induced by augmented expression of p56lck.
    Abraham KM, Levin SD, Marth JD, Forbush KA, Perlmutter RM.
    J Exp Med; 1991 Jun 01; 173(6):1421-32. PubMed ID: 1709675
    [Abstract] [Full Text] [Related]

  • 13. Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.
    Stephen TL, Wilson BS, Laufer TM.
    Proc Natl Acad Sci U S A; 2012 May 08; 109(19):7415-20. PubMed ID: 22529380
    [Abstract] [Full Text] [Related]

  • 14. Human CD4 expression at the late single-positive stage of thymic development supports T cell maturation and peripheral export in CD4-deficient mice.
    Boyer O, Marodon G, Cohen JL, Lejeune L, Irinopoulou T, Liblau R, Bruneval P, Klatzmann D.
    J Immunol; 2002 Oct 15; 169(8):4347-53. PubMed ID: 12370367
    [Abstract] [Full Text] [Related]

  • 15. Defective thymocyte maturation by transgenic expression of a truncated form of the T lymphocyte adapter molecule and Fyn substrate, Sin.
    Donlin LT, Roman CA, Adlam M, Regelmann AG, Alexandropoulos K.
    J Immunol; 2002 Dec 15; 169(12):6900-9. PubMed ID: 12471123
    [Abstract] [Full Text] [Related]

  • 16. p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function.
    Henning SW, Cantrell DA.
    J Exp Med; 1998 Sep 07; 188(5):931-9. PubMed ID: 9730894
    [Abstract] [Full Text] [Related]

  • 17. MEK activity regulates negative selection of immature CD4+CD8+ thymocytes.
    Bommhardt U, Scheuring Y, Bickel C, Zamoyska R, Hünig T.
    J Immunol; 2000 Mar 01; 164(5):2326-37. PubMed ID: 10679067
    [Abstract] [Full Text] [Related]

  • 18. CD4 and CD8: hogging all the Lck.
    Kappes DJ.
    Immunity; 2007 Nov 01; 27(5):691-3. PubMed ID: 18031691
    [Abstract] [Full Text] [Related]

  • 19. An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.
    Mombaerts P, Anderson SJ, Perlmutter RM, Mak TW, Tonegawa S.
    Immunity; 1994 Jul 01; 1(4):261-7. PubMed ID: 7889413
    [Abstract] [Full Text] [Related]

  • 20. Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor.
    Norment AM, Forbush KA, Nguyen N, Malissen M, Perlmutter RM.
    J Exp Med; 1997 Jan 06; 185(1):121-30. PubMed ID: 8996248
    [Abstract] [Full Text] [Related]

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