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417 related items for PubMed ID: 11145953

  • 1. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells.
    Panka DJ, Mano T, Suhara T, Walsh K, Mier JW.
    J Biol Chem; 2001 Mar 09; 276(10):6893-6. PubMed ID: 11145953
    [Abstract] [Full Text] [Related]

  • 2. Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).
    Suhara T, Mano T, Oliveira BE, Walsh K.
    Circ Res; 2001 Jul 06; 89(1):13-9. PubMed ID: 11440972
    [Abstract] [Full Text] [Related]

  • 3. Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance.
    Thakkar H, Chen X, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK.
    J Biol Chem; 2001 Oct 19; 276(42):38361-9. PubMed ID: 11461904
    [Abstract] [Full Text] [Related]

  • 4. Blocking of c-FLIP(L)--independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction.
    Youn BS, Kim YJ, Mantel C, Yu KY, Broxmeyer HE.
    Blood; 2001 Aug 15; 98(4):925-33. PubMed ID: 11493434
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis.
    Madge LA, Li JH, Choi J, Pober JS.
    J Biol Chem; 2003 Jun 06; 278(23):21295-306. PubMed ID: 12663669
    [Abstract] [Full Text] [Related]

  • 6. Tumor necrosis factor-alpha supports the survival of osteoclasts through the activation of Akt and ERK.
    Lee SE, Chung WJ, Kwak HB, Chung CH, Kwack KB, Lee ZH, Kim HH.
    J Biol Chem; 2001 Dec 28; 276(52):49343-9. PubMed ID: 11675379
    [Abstract] [Full Text] [Related]

  • 7. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM, Tazzari PL, Tabellini G, Bortul R, Billi AM, Manzoli L, Ruggeri A, Conte R, Cocco L.
    Leukemia; 2003 Sep 28; 17(9):1794-805. PubMed ID: 12970779
    [Abstract] [Full Text] [Related]

  • 8. TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2.
    Alladina SJ, Song JH, Davidge ST, Hao C, Easton AS.
    J Vasc Res; 2005 Sep 28; 42(4):337-47. PubMed ID: 15985761
    [Abstract] [Full Text] [Related]

  • 9. Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer.
    Chen X, Thakkar H, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK.
    Oncogene; 2001 Sep 20; 20(42):6073-83. PubMed ID: 11593415
    [Abstract] [Full Text] [Related]

  • 10. The Akt-regulated forkhead transcription factor FOXO3a controls endothelial cell viability through modulation of the caspase-8 inhibitor FLIP.
    Skurk C, Maatz H, Kim HS, Yang J, Abid MR, Aird WC, Walsh K.
    J Biol Chem; 2004 Jan 09; 279(2):1513-25. PubMed ID: 14551207
    [Abstract] [Full Text] [Related]

  • 11. Serum bioactive lysophospholipids prevent TRAIL-induced apoptosis via PI3K/Akt-dependent cFLIP expression and Bad phosphorylation.
    Kang YC, Kim KM, Lee KS, Namkoong S, Lee SJ, Han JA, Jeoung D, Ha KS, Kwon YG, Kim YM.
    Cell Death Differ; 2004 Dec 09; 11(12):1287-98. PubMed ID: 15297884
    [Abstract] [Full Text] [Related]

  • 12. The molecular mechanism of sensitization to Fas-mediated apoptosis by 2-methoxyestradiol in PC3 prostate cancer cells.
    Shimada K, Nakamura M, Ishida E, Kishi M, Matsuyoshi S, Konishi N.
    Mol Carcinog; 2004 Jan 09; 39(1):1-9. PubMed ID: 14694442
    [Abstract] [Full Text] [Related]

  • 13. Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.
    Somervaille TC, Linch DC, Khwaja A.
    Blood; 2001 Sep 01; 98(5):1374-81. PubMed ID: 11520785
    [Abstract] [Full Text] [Related]

  • 14. Caspase-8 activation is necessary but not sufficient for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in the prostatic carcinoma cell line LNCaP.
    Rokhlin OW, Guseva NV, Tagiyev AF, Glover RA, Cohen MB.
    Prostate; 2002 Jun 01; 52(1):1-11. PubMed ID: 11992615
    [Abstract] [Full Text] [Related]

  • 15. Calcium/calmodulin-dependent protein kinase II regulation of c-FLIP expression and phosphorylation in modulation of Fas-mediated signaling in malignant glioma cells.
    Yang BF, Xiao C, Roa WH, Krammer PH, Hao C.
    J Biol Chem; 2003 Feb 28; 278(9):7043-50. PubMed ID: 12496285
    [Abstract] [Full Text] [Related]

  • 16. Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
    Song JH, Bellail A, Tse MC, Yong VW, Hao C.
    J Neurosci; 2006 Mar 22; 26(12):3299-308. PubMed ID: 16554480
    [Abstract] [Full Text] [Related]

  • 17. Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.
    Zhang HM, Yuan J, Cheung P, Luo H, Yanagawa B, Chau D, Stephan-Tozy N, Wong BW, Zhang J, Wilson JE, McManus BM, Yang D.
    J Biol Chem; 2003 Aug 29; 278(35):33011-9. PubMed ID: 12819192
    [Abstract] [Full Text] [Related]

  • 18. Cripto-1 induces phosphatidylinositol 3'-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells.
    Ebert AD, Wechselberger C, Frank S, Wallace-Jones B, Seno M, Martinez-Lacaci I, Bianco C, De Santis M, Weitzel HK, Salomon DS.
    Cancer Res; 1999 Sep 15; 59(18):4502-5. PubMed ID: 10493495
    [Abstract] [Full Text] [Related]

  • 19. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C, Rahmani M, Dai Y, Conrad D, Krystal G, Dent P, Grant S.
    Cancer Res; 2003 Apr 15; 63(8):1822-33. PubMed ID: 12702569
    [Abstract] [Full Text] [Related]

  • 20. Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes.
    Uriarte SM, Joshi-Barve S, Song Z, Sahoo R, Gobejishvili L, Jala VR, Haribabu B, McClain C, Barve S.
    Cell Death Differ; 2005 Mar 15; 12(3):233-42. PubMed ID: 15665818
    [Abstract] [Full Text] [Related]


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