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343 related items for PubMed ID: 11146160

  • 1. Combined corticosteroid/granulocyte colony-stimulating factor (G-CSF) therapy in the treatment of severe congenital neutropenia unresponsive to G-CSF: Activated glucocorticoid receptors synergize with G-CSF signals.
    Dror Y, Ward AC, Touw IP, Freedman MH.
    Exp Hematol; 2000 Dec; 28(12):1381-9. PubMed ID: 11146160
    [Abstract] [Full Text] [Related]

  • 2. Increased granulocyte colony-stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony-stimulating factor receptor mutation derived from a patient with severe congenital neutropenia.
    McLemore ML, Poursine-Laurent J, Link DC.
    J Clin Invest; 1998 Aug 01; 102(3):483-92. PubMed ID: 9691084
    [Abstract] [Full Text] [Related]

  • 3. Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene.
    Hermans MH, Antonissen C, Ward AC, Mayen AE, Ploemacher RE, Touw IP.
    J Exp Med; 1999 Feb 15; 189(4):683-92. PubMed ID: 9989983
    [Abstract] [Full Text] [Related]

  • 4. Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment.
    Ward AC, van Aesch YM, Gits J, Schelen AM, de Koning JP, van Leeuwen D, Freedman MH, Touw IP.
    J Exp Med; 1999 Aug 16; 190(4):497-507. PubMed ID: 10449521
    [Abstract] [Full Text] [Related]

  • 5. Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia.
    Druhan LJ, Ai J, Massullo P, Kindwall-Keller T, Ranalli MA, Avalos BR.
    Blood; 2005 Jan 15; 105(2):584-91. PubMed ID: 15353486
    [Abstract] [Full Text] [Related]

  • 6. Defects of granulopoiesis in patients with severe congenital neutropenia.
    Nakamura K, Kobayashi M, Konishi N, Kawaguchi H, Miyagawa S, Sato T, Katoh O, Ueda K.
    Hiroshima J Med Sci; 2002 Sep 15; 51(3):63-74. PubMed ID: 12422946
    [Abstract] [Full Text] [Related]

  • 7. The granulocyte colony-stimulating factor receptor supports erythroid differentiation in the absence of the erythropoietin receptor or Stat5.
    Millot GA, Svinarchuk F, Lacout C, Vainchenker W, Dumenil D.
    Br J Haematol; 2001 Feb 15; 112(2):449-58. PubMed ID: 11167846
    [Abstract] [Full Text] [Related]

  • 8. Abnormalities of primitive myeloid progenitor cells expressing granulocyte colony-stimulating factor receptor in patients with severe congenital neutropenia.
    Nakamura K, Kobayashi M, Konishi N, Kawaguchi H, Miyagawa S, Sato T, Toyoda H, Komada Y, Kojima S, Katoh O, Ueda K.
    Blood; 2000 Dec 15; 96(13):4366-9. PubMed ID: 11110716
    [Abstract] [Full Text] [Related]

  • 9. Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia.
    Dong F, Brynes RK, Tidow N, Welte K, Löwenberg B, Touw IP.
    N Engl J Med; 1995 Aug 24; 333(8):487-93. PubMed ID: 7542747
    [Abstract] [Full Text] [Related]

  • 10. Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia.
    Tidow N, Pilz C, Teichmann B, Müller-Brechlin A, Germeshausen M, Kasper B, Rauprich P, Sykora KW, Welte K.
    Blood; 1997 Apr 01; 89(7):2369-75. PubMed ID: 9116280
    [Abstract] [Full Text] [Related]

  • 11. G-CSF receptor truncations found in SCN/AML relieve SOCS3-controlled inhibition of STAT5 but leave suppression of STAT3 intact.
    van de Geijn GJ, Gits J, Aarts LH, Heijmans-Antonissen C, Touw IP.
    Blood; 2004 Aug 01; 104(3):667-74. PubMed ID: 15069015
    [Abstract] [Full Text] [Related]

  • 12. Thrombopoietin enhances neutrophil production by bone marrow hematopoietic progenitors with the aid of stem cell factor in congenital neutropenia.
    Sawai N, Koike K, Mwamtemi HH, Ito S, Kurokawa Y, Sakashita K, Kinoshita T, Higuchi T, Takeuchi K, Shiohara M, Kamijo T, Higuchi Y, Miyazaki H, Kato T, Kobayashi M, Miyake M, Yasui K, Komiyama A.
    J Leukoc Biol; 2000 Jul 01; 68(1):137-43. PubMed ID: 10914501
    [Abstract] [Full Text] [Related]

  • 13. Loss of SHIP and CIS recruitment to the granulocyte colony-stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia/acute myelogenous leukemia.
    Hunter MG, Jacob A, O'donnell LC, Agler A, Druhan LJ, Coggeshall KM, Avalos BR.
    J Immunol; 2004 Oct 15; 173(8):5036-45. PubMed ID: 15470047
    [Abstract] [Full Text] [Related]

  • 14. Deletional mutation of the external domain of the human granulocyte colony-stimulating factor receptor in a patient with severe chronic neutropenia refractory to granulocyte colony-stimulating factor.
    Sinha S, Zhu QS, Romero G, Corey SJ.
    J Pediatr Hematol Oncol; 2003 Oct 15; 25(10):791-6. PubMed ID: 14528102
    [Abstract] [Full Text] [Related]

  • 15. Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration.
    Ward AC, Hermans MH, Smith L, van Aesch YM, Schelen AM, Antonissen C, Touw IP.
    Blood; 1999 Jan 01; 93(1):113-24. PubMed ID: 9864153
    [Abstract] [Full Text] [Related]

  • 16. Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia.
    Ward AC, van Aesch YM, Schelen AM, Touw IP.
    Blood; 1999 Jan 15; 93(2):447-58. PubMed ID: 9885206
    [Abstract] [Full Text] [Related]

  • 17. Delineation and mapping of Stat5 isoforms activated by granulocyte colony-stimulating factor in myeloid cells.
    Chakraborty A, Dyer KF, Tweardy DJ.
    Blood Cells Mol Dis; 2000 Aug 15; 26(4):320-30. PubMed ID: 11042034
    [Abstract] [Full Text] [Related]

  • 18. Bivalent binding and signaling characteristics of Leridistim, a novel chimeric dual agonist of interleukin-3 and granulocyte colony-stimulating factor receptors.
    Monahan JB, Hood WF, Welply JK, Shieh JJ, Polazzi JO, Li X.
    Exp Hematol; 2001 Apr 15; 29(4):416-24. PubMed ID: 11301181
    [Abstract] [Full Text] [Related]

  • 19. The G-CSF receptor carboxyl terminus, truncated in AML/SCN, is required for induction of a Stat5 protease activity.
    Qiu Y, Zhuang D, MacRae A, Dong F.
    Leuk Res; 2005 Oct 15; 29(10):1153-62. PubMed ID: 16111533
    [Abstract] [Full Text] [Related]

  • 20. A novel mutation in the juxtamembrane intracellular sequence of the granulocyte colony-stimulating factor (G-CSF) receptor gene in a patient with severe congenital neutropenia augments GCSF proliferation activity but not through the MAP kinase cascade.
    Yokoyama T, Okamura S, Asano Y, Kamezaki K, Numata A, Kakumitsu H, Shide K, Nakashima H, Taisuke K, Sekine Y, Mizuno Y, Okamura J, Matsuda T, Harada M, Yoshiyuki N, Shimoda K.
    Int J Hematol; 2005 Jul 15; 82(1):28-34. PubMed ID: 16229088
    [Abstract] [Full Text] [Related]

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