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213 related items for PubMed ID: 11158349

  • 1. Construction and analysis of ss-lactamase-inhibitory protein (BLIP) non-producer mutants of Streptomyces clavuligerus.
    Thai W, Paradkar AS, Jensen SE.
    Microbiology (Reading); 2001 Feb; 147(Pt 2):325-335. PubMed ID: 11158349
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  • 2. Expression of ccaR, encoding the positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus, is dependent on bldG.
    Bignell DR, Tahlan K, Colvin KR, Jensen SE, Leskiw BK.
    Antimicrob Agents Chemother; 2005 Apr; 49(4):1529-41. PubMed ID: 15793135
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  • 3. An rplKDelta29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus.
    Gomez-Escribano JP, Liras P, Pisabarro A, Martín JF.
    Mol Microbiol; 2006 Aug; 61(3):758-70. PubMed ID: 16803595
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  • 4. A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds.
    Pérez-Llarena FJ, Liras P, Rodríguez-García A, Martín JF.
    J Bacteriol; 1997 Mar; 179(6):2053-9. PubMed ID: 9068654
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  • 5. A gene located downstream of the clavulanic acid gene cluster in Streptomyces clavuligerus ATCC 27064 encodes a putative response regulator that affects clavulanic acid production.
    Song JY, Kim ES, Kim DW, Jensen SE, Lee KJ.
    J Ind Microbiol Biotechnol; 2009 Feb; 36(2):301-11. PubMed ID: 19011915
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  • 6. The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene.
    Pérez-Redondo R, Rodríguez-García A, Martín JF, Liras P.
    Gene; 1998 May 12; 211(2):311-21. PubMed ID: 9602162
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  • 7. The positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is mistranslated in a bldA mutant.
    Trepanier NK, Jensen SE, Alexander DC, Leskiw BK.
    Microbiology (Reading); 2002 Mar 12; 148(Pt 3):643-656. PubMed ID: 11882698
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  • 8. Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus.
    Mosher RH, Paradkar AS, Anders C, Barton B, Jensen SE.
    Antimicrob Agents Chemother; 1999 May 12; 43(5):1215-24. PubMed ID: 10223939
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  • 9. Transcriptional Studies on a Streptomyces clavuligerus oppA2 Deletion Mutant: N-Acetylglycyl-Clavaminic Acid Is an Intermediate of Clavulanic Acid Biosynthesis.
    Álvarez-Álvarez R, Rodríguez-García A, Martínez-Burgo Y, Martín JF, Liras P.
    Appl Environ Microbiol; 2018 Nov 15; 84(22):. PubMed ID: 30194098
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  • 12. Applications of gene replacement technology to Streptomyces clavuligerus strain development for clavulanic acid production.
    Paradkar AS, Mosher RH, Anders C, Griffin A, Griffin J, Hughes C, Greaves P, Barton B, Jensen SE.
    Appl Environ Microbiol; 2001 May 15; 67(5):2292-7. PubMed ID: 11319114
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  • 17. Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp.
    Gomez-Escribano JP, Martín JF, Hesketh A, Bibb MJ, Liras P.
    Microbiology (Reading); 2008 Mar 15; 154(Pt 3):744-755. PubMed ID: 18310021
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  • 18. Insight into Structure-Function Relationships of β-Lactamase and BLIPs Interface Plasticity using Protein-Protein Interactions.
    Yadav TC, Agarwal V, Srivastava AK, Raghuwanshi N, Varadwaj P, Prasad R, Pruthi V.
    Curr Pharm Des; 2019 Mar 15; 25(31):3378-3389. PubMed ID: 31544712
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  • 20. Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways.
    de la Fuente A, Lorenzana LM, Martín JF, Liras P.
    J Bacteriol; 2002 Dec 15; 184(23):6559-65. PubMed ID: 12426344
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