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175 related items for PubMed ID: 11159748

  • 1. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
    Prokopczyk B, Trushin N, Leszczynska J, Waggoner SE, El-Bayoumy K.
    Carcinogenesis; 2001 Jan; 22(1):107-14. PubMed ID: 11159748
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  • 2. Carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in cytosol of mouse liver and lung.
    Atalla A, Maser E.
    Toxicology; 1999 Nov 29; 139(1-2):155-66. PubMed ID: 10614696
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  • 4. Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reductase important in (R)-NNAL formation in human lung.
    Ashmore JH, Luo S, Watson CJW, Lazarus P.
    Carcinogenesis; 2018 Jul 30; 39(8):1079-1088. PubMed ID: 29788210
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  • 5. Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
    Staretz ME, Murphy SE, Patten CJ, Nunes MG, Koehl W, Amin S, Koenig LA, Guengerich FP, Hecht SS.
    Drug Metab Dispos; 1997 Feb 30; 25(2):154-62. PubMed ID: 9029045
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  • 6. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E, Engl J, Friesenegger S, Tricker AR.
    Chem Res Toxicol; 2009 Jun 30; 22(6):1008-17. PubMed ID: 19408892
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  • 7. Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver.
    Breyer-Pfaff U, Martin HJ, Ernst M, Maser E.
    Drug Metab Dispos; 2004 Sep 30; 32(9):915-22. PubMed ID: 15319331
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  • 9. The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols.
    Trushin N, Leder G, El-Bayoumy K, Hoffmann D, Beger HG, Henne-Bruns D, Ramadani M, Prokopczyk B.
    Langenbecks Arch Surg; 2008 Jul 30; 393(4):571-9. PubMed ID: 18259773
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  • 10. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.
    Collazo NR, Sultatos LG.
    Biochem Pharmacol; 1995 Nov 27; 50(11):1933-41. PubMed ID: 8615875
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  • 13. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Smith TJ, Liao AM, Liu Y, Jones AB, Anderson LM, Yang CS.
    Carcinogenesis; 1997 Aug 27; 18(8):1577-84. PubMed ID: 9276633
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  • 15. Carbonyl reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytosolic enzymes in human liver and lung.
    Maser E, Stinner B, Atalla A.
    Cancer Lett; 2000 Feb 01; 148(2):135-44. PubMed ID: 10695989
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  • 16. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Smith TJ, Stoner GD, Yang CS.
    Cancer Res; 1995 Dec 01; 55(23):5566-73. PubMed ID: 7585636
    [Abstract] [Full Text] [Related]

  • 17. Formation of NADP(H) analogs of tobacco-specific nitrosamines in rat liver and pancreatic microsomes.
    Peterson LA, Ng DK, Stearns RA, Hecht SS.
    Chem Res Toxicol; 1994 Dec 01; 7(5):599-608. PubMed ID: 7841337
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  • 19. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
    Jalas JR, Ding X, Murphy SE.
    Drug Metab Dispos; 2003 Oct 01; 31(10):1199-202. PubMed ID: 12975327
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  • 20. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
    Guo Z, Smith TJ, Thomas PE, Yang CS.
    Arch Biochem Biophys; 1992 Oct 01; 298(1):279-86. PubMed ID: 1524438
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