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Journal Abstract Search


268 related items for PubMed ID: 11159809

  • 1. Stereochemical aspects of vinylcyclohexene bioactivation in rodent hepatic microsomes and purified human cytochrome P450 enzyme systems.
    Fontaine SM, Mash EA, Hoyer PB, Sipes IG.
    Drug Metab Dispos; 2001 Feb; 29(2):179-84. PubMed ID: 11159809
    [Abstract] [Full Text] [Related]

  • 2. Role of induction of specific hepatic cytochrome P450 isoforms in epoxidation of 4-vinylcyclohexene.
    Fontaine SM, Hoyer PB, Halpert JR, Sipes IG.
    Drug Metab Dispos; 2001 Sep; 29(9):1236-42. PubMed ID: 11502734
    [Abstract] [Full Text] [Related]

  • 3. Stereochemical aspects in the 4-vinylcyclohexene biotransformation with rat liver microsomes and purified cytochrome P450s: diepoxide formation and hydrolysis.
    Chiappe C, De Rubertis A, Piegari G, Amato G, Gervasi PG.
    Chem Res Toxicol; 2003 Jan; 16(1):56-65. PubMed ID: 12693031
    [Abstract] [Full Text] [Related]

  • 4. In vitro metabolism of 4-vinylcyclohexene in rat and mouse liver, lung, and ovary.
    Keller DA, Carpenter SC, Cagen SZ, Reitman FA.
    Toxicol Appl Pharmacol; 1997 May; 144(1):36-44. PubMed ID: 9169067
    [Abstract] [Full Text] [Related]

  • 5. Induction of cytochrome P-450 enzymes after repeated exposure to 4-vinylcyclohexene in B6C3F1 mice.
    Doerr-Stevens JK, Liu J, Stevens GJ, Kraner JC, Fontaine SM, Halpert JR, Sipes IG.
    Drug Metab Dispos; 1999 Feb; 27(2):281-7. PubMed ID: 9929517
    [Abstract] [Full Text] [Related]

  • 6. Evaluation of hepatic cytochrome P4502E1 in the species-dependent bioactivation of 4-vinylcyclohexene.
    Fontaine SM, Hoyer PB, Sipes IG.
    Life Sci; 2001 Jul 13; 69(8):923-34. PubMed ID: 11488405
    [Abstract] [Full Text] [Related]

  • 7. Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: the effect of 4-vinylcyclohexene and its diepoxide metabolite.
    Cannady EA, Dyer CA, Christian PJ, Sipes IG, Hoyer PB.
    Toxicol Sci; 2003 Jun 13; 73(2):423-30. PubMed ID: 12700394
    [Abstract] [Full Text] [Related]

  • 8. Stereochemical aspects in the 4-vinylcyclohexene biotransformation with rat liver microsomes and purified p450s. monoepoxides and diols.
    Chiappe C, De Rubertis A, De Carlo M, Amato G, Gervasi PG.
    Chem Res Toxicol; 2001 May 13; 14(5):492-9. PubMed ID: 11368546
    [Abstract] [Full Text] [Related]

  • 9. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM, Oudshoorn MJ, Van Ommen B, Haenen GR, Van Bladeren PJ.
    Chem Res Toxicol; 1996 Dec 13; 9(8):1249-56. PubMed ID: 8951226
    [Abstract] [Full Text] [Related]

  • 10. The biotransformation of isoprene and the two isoprene monoepoxides by human cytochrome P450 enzymes, compared to mouse and rat liver microsomes.
    Bogaards JJ, Venekamp JC, van Bladeren PJ.
    Chem Biol Interact; 1996 Dec 20; 102(3):169-82. PubMed ID: 9021169
    [Abstract] [Full Text] [Related]

  • 11. The biochemical basis for the species difference in hepatic microsomal 4-vinylcyclohexene epoxidation between female mice and rats.
    Smith BJ, Sipes IG, Stevens JC, Halpert JR.
    Carcinogenesis; 1990 Nov 20; 11(11):1951-7. PubMed ID: 2225327
    [Abstract] [Full Text] [Related]

  • 12. Ovarian toxicity of 4-vinylcyclohexene and related olefins in B6C3F1 mice: role of diepoxides.
    Doerr JK, Hooser SB, Smith BJ, Sipes IG.
    Chem Res Toxicol; 1995 Nov 20; 8(7):963-9. PubMed ID: 8555412
    [Abstract] [Full Text] [Related]

  • 13. Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index.
    Borman SM, Christian PJ, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2000 Sep 15; 167(3):191-8. PubMed ID: 10986010
    [Abstract] [Full Text] [Related]

  • 14. Epoxidation of 4-vinylcyclohexene by human hepatic microsomes.
    Smith BJ, Sipes IG.
    Toxicol Appl Pharmacol; 1991 Jun 15; 109(2):367-71. PubMed ID: 2068732
    [Abstract] [Full Text] [Related]

  • 15. Stereochemical and kinetic comparisons of mono- and diepoxide formation in the in vitro metabolism of isoprene by liver microsomes from rats, mice, and humans.
    Golding BT, Cottrell L, Mackay D, Zhang D, Watson WP.
    Chem Res Toxicol; 2003 Jul 15; 16(7):933-44. PubMed ID: 12870896
    [Abstract] [Full Text] [Related]

  • 16. Development of an animal model for ovotoxicity using 4-vinylcyclohexene: a case study.
    Hoyer PB, Sipes IG.
    Birth Defects Res B Dev Reprod Toxicol; 2007 Apr 15; 80(2):113-25. PubMed ID: 17342769
    [Abstract] [Full Text] [Related]

  • 17. Comparison of the disposition and in vitro metabolism of 4-vinylcyclohexene in the female mouse and rat.
    Smith BJ, Carter DE, Sipes IG.
    Toxicol Appl Pharmacol; 1990 Sep 15; 105(3):364-71. PubMed ID: 2237911
    [Abstract] [Full Text] [Related]

  • 18. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 15; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

  • 19. Cytochrome P-450-dependent bioactivation of 1,1-dichloroethylene to a reactive epoxide in human lung and liver microsomes.
    Dowsley TF, Reid K, Petsikas D, Ulreich JB, Fisher RL, Forkert PG.
    J Pharmacol Exp Ther; 1999 May 15; 289(2):641-8. PubMed ID: 10215634
    [Abstract] [Full Text] [Related]

  • 20. Characterization of verlukast metabolites arising from an epoxide intermediate produced with hepatic microsomes from beta-naphthoflavone-treated rodents (P-4501A1).
    Nicoll-Griffith DA, Chauret N, Yergey JA, Trimble LA, Favreau L, Zamboni R, Grossman SJ, Drey J, Herold E.
    Drug Metab Dispos; 1993 May 15; 21(5):861-7. PubMed ID: 7902249
    [Abstract] [Full Text] [Related]


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