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Journal Abstract Search

46 related items for PubMed ID: 11159810

  • 1. Methanol solvent may cause increased apparent metabolic instability in in vitro assays.
    Yin H, Tran P, Greenberg GE, Fischer V.
    Drug Metab Dispos; 2001 Feb; 29(2):185-93. PubMed ID: 11159810
    [Abstract] [Full Text] [Related]

  • 2. Identification of a novel in vitro metabonate from liver microsomal incubations.
    Li C, Surapaneni S, Zeng Q, Marquez B, Chow D, Kumar G.
    Drug Metab Dispos; 2006 Jun; 34(6):901-5. PubMed ID: 16554371
    [Abstract] [Full Text] [Related]

  • 3. Effect of regular organic solvents on cytochrome P450-mediated metabolic activities in rat liver microsomes.
    Li D, Han Y, Meng X, Sun X, Yu Q, Li Y, Wan L, Huo Y, Guo C.
    Drug Metab Dispos; 2010 Nov; 38(11):1922-5. PubMed ID: 20729275
    [Abstract] [Full Text] [Related]

  • 4. 3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid.
    Deo AK, Bandiera SM.
    Drug Metab Dispos; 2009 Sep; 37(9):1938-47. PubMed ID: 19487251
    [Abstract] [Full Text] [Related]

  • 5. In vitro metabolism of BYZX in human liver microsomes and the structural elucidation of metabolite by liquid chromatography-mass spectrometry method.
    Xia ZL, Ying JY, Sheng R, Zeng S, Hu YZ, Yao TW.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Oct 01; 857(2):266-74. PubMed ID: 17709305
    [Abstract] [Full Text] [Related]

  • 6. CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
    Prakash C, Wang W, O'Connell T, Johnson KA.
    Drug Metab Dispos; 2008 Oct 01; 36(10):2093-103. PubMed ID: 18653741
    [Abstract] [Full Text] [Related]

  • 7. Catalyzation of cocaine N-demethylation by cytochromes P4502B, P4503A, and P4502D in fish liver.
    Arinç E, Bozcaarmutlu A.
    J Biochem Mol Toxicol; 2003 Oct 01; 17(3):169-76. PubMed ID: 12815613
    [Abstract] [Full Text] [Related]

  • 8. Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: a case study with melanocortin-4 receptor agonists.
    Tang W, Stearns RA, Wang RW, Miller RR, Chen Q, Ngui J, Bakshi RK, Nargund RP, Dean DC, Baillie TA.
    Xenobiotica; 2008 Nov 01; 38(11):1437-51. PubMed ID: 18841517
    [Abstract] [Full Text] [Related]

  • 9. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2001 Feb 01; 29(2):200-5. PubMed ID: 11159812
    [Abstract] [Full Text] [Related]

  • 10. Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes.
    Abass K, Reponen P, Turpeinen M, Jalonen J, Pelkonen O.
    Drug Metab Dispos; 2007 Sep 01; 35(9):1634-41. PubMed ID: 17576805
    [Abstract] [Full Text] [Related]

  • 11. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 01; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

  • 12. In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam.
    Tang J, Amin Usmani K, Hodgson E, Rose RL.
    Chem Biol Interact; 2004 Apr 15; 147(3):319-29. PubMed ID: 15135087
    [Abstract] [Full Text] [Related]

  • 13. A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation.
    Grillo MP, Ma J, Teffera Y, Waldon DJ.
    Drug Metab Dispos; 2008 Sep 15; 36(9):1740-4. PubMed ID: 18541695
    [Abstract] [Full Text] [Related]

  • 14. Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450.
    Miller KK, Cai J, Ripp SL, Pierce WM, Rushmore TH, Prough RA.
    Drug Metab Dispos; 2004 Mar 15; 32(3):305-13. PubMed ID: 14977864
    [Abstract] [Full Text] [Related]

  • 15. Human hepatic cytochrome p450-specific metabolism of parathion and chlorpyrifos.
    Foxenberg RJ, McGarrigle BP, Knaak JB, Kostyniak PJ, Olson JR.
    Drug Metab Dispos; 2007 Feb 15; 35(2):189-93. PubMed ID: 17079358
    [Abstract] [Full Text] [Related]

  • 16. Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes.
    Hanioka N, Yamamoto M, Iwabu H, Jinno H, Tanaka-Kagawa T, Naito S, Shimizu T, Masuda K, Katsu T, Narimatsu S.
    Life Sci; 2007 Oct 27; 81(19-20):1436-45. PubMed ID: 17935737
    [Abstract] [Full Text] [Related]

  • 17. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
    Zhao SX, Dalvie DK, Kelly JM, Soglia JR, Frederick KS, Smith EB, Obach RS, Kalgutkar AS.
    Chem Res Toxicol; 2007 Nov 27; 20(11):1649-57. PubMed ID: 17907785
    [Abstract] [Full Text] [Related]

  • 18. Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro.
    Dai Y, Hebert MF, Isoherranen N, Davis CL, Marsh C, Shen DD, Thummel KE.
    Drug Metab Dispos; 2006 May 27; 34(5):836-47. PubMed ID: 16501005
    [Abstract] [Full Text] [Related]

  • 19. Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes.
    Li W, Liu Y, He YQ, Zhang JW, Gao Y, Ge GB, Liu HX, Huo H, Liu HT, Wang LM, Sun J, Wang Q, Yang L.
    Xenobiotica; 2008 Dec 27; 38(12):1551-65. PubMed ID: 18982531
    [Abstract] [Full Text] [Related]

  • 20. Stereoselective metabolism of cisapride and enantiomer-enantiomer interaction in human cytochrome P450 enzymes: major role of CYP3A.
    Desta Z, Soukhova N, Morocho AM, Flockhart DA.
    J Pharmacol Exp Ther; 2001 Aug 27; 298(2):508-20. PubMed ID: 11454912
    [Abstract] [Full Text] [Related]

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