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90 related items for PubMed ID: 11162245

  • 1. Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum.
    Kim GW, Chan PH.
    Neurobiol Dis; 2001 Feb; 8(1):114-26. PubMed ID: 11162245
    [Abstract] [Full Text] [Related]

  • 2. Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid.
    Kim GW, Copin JC, Kawase M, Chen SF, Sato S, Gobbel GT, Chan PH.
    J Cereb Blood Flow Metab; 2000 Jan; 20(1):119-29. PubMed ID: 10616800
    [Abstract] [Full Text] [Related]

  • 3. Enhanced expression of C/EBP homologous protein (CHOP) precedes degeneration of fibrocytes in the lateral wall after acute cochlear mitochondrial dysfunction induced by 3-nitropropionic acid.
    Fujinami Y, Mutai H, Kamiya K, Mizutari K, Fujii M, Matsunaga T.
    Neurochem Int; 2010 Feb; 56(3):487-94. PubMed ID: 20026213
    [Abstract] [Full Text] [Related]

  • 4. Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid.
    Kim GW, Chan PH.
    J Cereb Blood Flow Metab; 2002 Jul; 22(7):798-809. PubMed ID: 12142565
    [Abstract] [Full Text] [Related]

  • 5. Metabolic compromise with systemic 3-nitropropionic acid produces striatal apoptosis in Sprague-Dawley rats but not in BALB/c ByJ mice.
    Alexi T, Hughes PE, Knüsel B, Tobin AJ.
    Exp Neurol; 1998 Sep; 153(1):74-93. PubMed ID: 9743569
    [Abstract] [Full Text] [Related]

  • 6. Creatine protects against 3-nitropropionic acid-induced cell death in murine corticostriatal slice cultures.
    Vis JC, de Boer-Van Huizen RT, Verbeek MM, de Waal RM, ten Donkelaar HJ, Kremer B.
    Brain Res; 2004 Oct 22; 1024(1-2):16-24. PubMed ID: 15451363
    [Abstract] [Full Text] [Related]

  • 7. Cytochrome c oxidase isoform IV-2 is involved in 3-nitropropionic acid-induced toxicity in striatal astrocytes.
    Singh S, Misiak M, Beyer C, Arnold S.
    Glia; 2009 Nov 01; 57(14):1480-91. PubMed ID: 19306371
    [Abstract] [Full Text] [Related]

  • 8. Whole body hyperthermia reduces oxidative stress in the striatum of rats in an animal model of mitochondrial toxicity with 3-nitropropionic acid.
    Medina-Navarro R, Guerrero-Linares I.
    Int J Hyperthermia; 2009 Jun 01; 25(4):280-8. PubMed ID: 19440936
    [Abstract] [Full Text] [Related]

  • 9. Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons.
    Almeida S, Brett AC, Góis IN, Oliveira CR, Rego AC.
    J Cell Biochem; 2006 May 01; 98(1):93-101. PubMed ID: 16365893
    [Abstract] [Full Text] [Related]

  • 10. Induction of apoptosis signal-regulating kinase 1 and oxidative stress mediate age-dependent vulnerability to 3-nitropropionic acid in the mouse striatum.
    Minn Y, Cho KJ, Kim HW, Kim HJ, Suk SH, Lee BI, Kim GW.
    Neurosci Lett; 2008 Jan 10; 430(2):142-6. PubMed ID: 18063477
    [Abstract] [Full Text] [Related]

  • 11. Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine.
    Silva-Adaya D, Pérez-De La Cruz V, Herrera-Mundo MN, Mendoza-Macedo K, Villeda-Hernández J, Binienda Z, Ali SF, Santamaría A.
    J Neurochem; 2008 May 10; 105(3):677-89. PubMed ID: 18194214
    [Abstract] [Full Text] [Related]

  • 12. FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures.
    Almeida S, Domingues A, Rodrigues L, Oliveira CR, Rego AC.
    Neurobiol Dis; 2004 Dec 10; 17(3):435-44. PubMed ID: 15571979
    [Abstract] [Full Text] [Related]

  • 13. Apoptosis in the striatum of rats following intraperitoneal injection of 3-nitropropionic acid.
    Sato S, Gobbel GT, Honkaniemi J, Li Y, Kondo T, Murakami K, Sato M, Copin JC, Chan PH.
    Brain Res; 1997 Jan 16; 745(1-2):343-7. PubMed ID: 9037431
    [Abstract] [Full Text] [Related]

  • 14. Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c From mitochondria in a rat forebrain ischemia model.
    Zhan RZ, Wu C, Fujihara H, Taga K, Qi S, Naito M, Shimoji K.
    J Cereb Blood Flow Metab; 2001 May 16; 21(5):529-40. PubMed ID: 11333363
    [Abstract] [Full Text] [Related]

  • 15. Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress.
    Diaz-Hernandez JI, Moncada S, Bolaños JP, Almeida A.
    Cell Death Differ; 2007 Jun 16; 14(6):1211-21. PubMed ID: 17347665
    [Abstract] [Full Text] [Related]

  • 16. Melatonin protects against neuronal damage induced by 3-nitropropionic acid in rat striatum.
    Nam E, Lee SM, Koh SE, Joo WS, Maeng S, Im HI, Kim YS.
    Brain Res; 2005 Jun 07; 1046(1-2):90-6. PubMed ID: 15882841
    [Abstract] [Full Text] [Related]

  • 17. Protective role of sertraline against 3-nitropropionic acid-induced cognitive dysfunction and redox ratio in striatum, cortex and hippocampus of rat brain.
    Kumar P, Kumar A.
    Indian J Exp Biol; 2009 Sep 07; 47(9):715-22. PubMed ID: 19957883
    [Abstract] [Full Text] [Related]

  • 18. Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's disease.
    Novikova L, Garris BL, Garris DR, Lau YS.
    Neuroscience; 2006 Jun 19; 140(1):67-76. PubMed ID: 16533572
    [Abstract] [Full Text] [Related]

  • 19. Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production.
    Villarán RF, Tomás-Camardiel M, de Pablos RM, Santiago M, Herrera AJ, Navarro A, Machado A, Cano J.
    Neurotoxicology; 2008 Mar 19; 29(2):244-58. PubMed ID: 18093658
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