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753 related items for PubMed ID: 11162513

  • 1. The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.
    Kimball SR, Clemens MJ, Tilleray VJ, Wek RC, Horetsky RL, Jefferson LS.
    Biochem Biophys Res Commun; 2001 Jan 12; 280(1):293-300. PubMed ID: 11162513
    [Abstract] [Full Text] [Related]

  • 2. Translational resistance of late alphavirus mRNA to eIF2alpha phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR.
    Ventoso I, Sanz MA, Molina S, Berlanga JJ, Carrasco L, Esteban M.
    Genes Dev; 2006 Jan 01; 20(1):87-100. PubMed ID: 16391235
    [Abstract] [Full Text] [Related]

  • 3. trans-Autophosphorylation by the isolated kinase domain is not sufficient for dimerization or activation of the dsRNA-activated protein kinase PKR.
    Wu S, Kaufman RJ.
    Biochemistry; 2004 Aug 31; 43(34):11027-34. PubMed ID: 15323561
    [Abstract] [Full Text] [Related]

  • 4. Phosphorylation of the alpha subunit of translation initiation factor-2 by PKR mediates protein synthesis inhibition in the mouse brain during status epilepticus.
    Carnevalli LS, Pereira CM, Jaqueta CB, Alves VS, Paiva VN, Vattem KM, Wek RC, Mello LE, Castilho BA.
    Biochem J; 2006 Jul 01; 397(1):187-94. PubMed ID: 16492139
    [Abstract] [Full Text] [Related]

  • 5. Nck-1 selectively modulates eIF2alphaSer51 phosphorylation by a subset of eIF2alpha-kinases.
    Cardin E, Latreille M, Khoury C, Greenwood MT, Larose L.
    FEBS J; 2007 Nov 01; 274(22):5865-75. PubMed ID: 17944934
    [Abstract] [Full Text] [Related]

  • 6. PKR; a sentinel kinase for cellular stress.
    Williams BR.
    Oncogene; 1999 Nov 01; 18(45):6112-20. PubMed ID: 10557102
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of protein synthesis in apoptosis: differential requirements by the tumor necrosis factor alpha family and a DNA-damaging agent for caspases and the double-stranded RNA-dependent protein kinase.
    Jeffrey IW, Bushell M, Tilleray VJ, Morley S, Clemens MJ.
    Cancer Res; 2002 Apr 15; 62(8):2272-80. PubMed ID: 11956083
    [Abstract] [Full Text] [Related]

  • 8. The Atlantic salmon Z-DNA binding protein kinase phosphorylates translation initiation factor 2 alpha and constitutes a unique orthologue to the mammalian dsRNA-activated protein kinase R.
    Bergan V, Jagus R, Lauksund S, Kileng Ø, Robertsen B.
    FEBS J; 2008 Jan 15; 275(1):184-97. PubMed ID: 18076653
    [Abstract] [Full Text] [Related]

  • 9. PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha.
    Dey M, Trieselmann B, Locke EG, Lu J, Cao C, Dar AC, Krishnamoorthy T, Dong J, Sicheri F, Dever TE.
    Mol Cell Biol; 2005 Apr 15; 25(8):3063-75. PubMed ID: 15798194
    [Abstract] [Full Text] [Related]

  • 10. Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase.
    Su Q, Wang S, Baltzis D, Qu LK, Wong AH, Koromilas AE.
    Proc Natl Acad Sci U S A; 2006 Jan 03; 103(1):63-8. PubMed ID: 16373505
    [Abstract] [Full Text] [Related]

  • 11. Resistance of mRNA translation to acute endoplasmic reticulum stress-inducing agents in herpes simplex virus type 1-infected cells requires multiple virus-encoded functions.
    Mulvey M, Arias C, Mohr I.
    J Virol; 2006 Aug 03; 80(15):7354-63. PubMed ID: 16840316
    [Abstract] [Full Text] [Related]

  • 12. Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR.
    Ung TL, Cao C, Lu J, Ozato K, Dever TE.
    EMBO J; 2001 Jul 16; 20(14):3728-37. PubMed ID: 11447114
    [Abstract] [Full Text] [Related]

  • 13. Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR.
    Kim SH, Forman AP, Mathews MB, Gunnery S.
    Oncogene; 2000 Jun 22; 19(27):3086-94. PubMed ID: 10871861
    [Abstract] [Full Text] [Related]

  • 14. PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking.
    Taylor SS, Haste NM, Ghosh G.
    Cell; 2005 Sep 23; 122(6):823-5. PubMed ID: 16179248
    [Abstract] [Full Text] [Related]

  • 15. The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro.
    Cuddihy AR, Wong AH, Tam NW, Li S, Koromilas AE.
    Oncogene; 1999 Apr 29; 18(17):2690-702. PubMed ID: 10348343
    [Abstract] [Full Text] [Related]

  • 16. Nck-1 interacts with PKR and modulates its activation by dsRNA.
    Cardin E, Larose L.
    Biochem Biophys Res Commun; 2008 Dec 05; 377(1):231-5. PubMed ID: 18835251
    [Abstract] [Full Text] [Related]

  • 17. Cell cycle regulation of the double stranded RNA activated protein kinase, PKR.
    Zamanian-Daryoush M, Der SD, Williams BR.
    Oncogene; 1999 Jan 14; 18(2):315-26. PubMed ID: 9927188
    [Abstract] [Full Text] [Related]

  • 18. Expression and purification of the alpha-subunit of eukaryotic initiation factor eIF2: use as a kinase substrate.
    Kimball SR, Horetsky RL, Jagus R, Jefferson LS.
    Protein Expr Purif; 1998 Apr 14; 12(3):415-9. PubMed ID: 9535710
    [Abstract] [Full Text] [Related]

  • 19. Coping with stress: eIF2 kinases and translational control.
    Wek RC, Jiang HY, Anthony TG.
    Biochem Soc Trans; 2006 Feb 14; 34(Pt 1):7-11. PubMed ID: 16246168
    [Abstract] [Full Text] [Related]

  • 20. PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway.
    Hamanaka RB, Bennett BS, Cullinan SB, Diehl JA.
    Mol Biol Cell; 2005 Dec 14; 16(12):5493-501. PubMed ID: 16176978
    [Abstract] [Full Text] [Related]

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