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190 related items for PubMed ID: 11170516

  • 1. Selenoxidation by flavin-containing monooxygenases as a novel pathway for beta-elimination of selenocysteine Se-conjugates.
    Rooseboom M, Commandeur JN, Floor GC, Rettie AE, Vermeulen NP.
    Chem Res Toxicol; 2001 Jan; 14(1):127-34. PubMed ID: 11170516
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  • 2. Bioactivation of chemopreventive selenocysteine Se-conjugates and related amino acids by amino acid oxidases novel route of metabolism of selenoamino acids.
    Rooseboom M, Vermeulen NP, van Hemert N, Commandeur JN.
    Chem Res Toxicol; 2001 Aug; 14(8):996-1005. PubMed ID: 11511173
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  • 3. Comparative study on the bioactivation mechanisms and cytotoxicity of Te-phenyl-L-tellurocysteine, Se-phenyl-L-selenocysteine, and S-phenyl-L-cysteine.
    Rooseboom M, Vermeulen NP, Durgut F, Commandeur JN.
    Chem Res Toxicol; 2002 Dec; 15(12):1610-8. PubMed ID: 12482244
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  • 4. Tissue distribution of cytosolic beta-elimination reactions of selenocysteine Se-conjugates in rat and human.
    Rooseboom M, Vermeulen NP, Groot EJ, Commandeur JN.
    Chem Biol Interact; 2002 Aug 15; 140(3):243-64. PubMed ID: 12204580
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  • 5. Oxidation of cysteine S-conjugates by rabbit liver microsomes and cDNA-expressed flavin-containing mono-oxygenases: studies with S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2,2-trichlorovinyl)-L-cysteine, S-allyl-L-cysteine, and S-benzyl-L-cysteine.
    Ripp SL, Overby LH, Philpot RM, Elfarra AA.
    Mol Pharmacol; 1997 Mar 15; 51(3):507-15. PubMed ID: 9058607
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  • 8. Evaluation of the kinetics of beta-elimination reactions of selenocysteine Se-conjugates in human renal cytosol: possible implications for the use as kidney selective prodrugs.
    Rooseboom M, Vermeulen NP, Andreadou I, Commandeur JN.
    J Pharmacol Exp Ther; 2000 Aug 15; 294(2):762-9. PubMed ID: 10900258
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  • 9. Studies on the inhibition of human cytochromes P450 by selenocysteine Se-conjugates.
    Venhorst J, Rooseboom M, Vermeulen NP, Commandeur JN.
    Xenobiotica; 2003 Jan 15; 33(1):57-72. PubMed ID: 12519694
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  • 10. The imidazoacridinone antitumor drug, C-1311, is metabolized by flavin monooxygenases but not by cytochrome P450s.
    Potega A, Dabrowska E, Niemira M, Kot-Wasik A, Ronseaux S, Henderson CJ, Wolf CR, Mazerska Z.
    Drug Metab Dispos; 2011 Aug 15; 39(8):1423-32. PubMed ID: 21555506
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  • 11. Sulfoxidation of cysteine and mercapturic acid conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A).
    Altuntas TG, Park SB, Kharasch ED.
    Chem Res Toxicol; 2004 Mar 15; 17(3):435-45. PubMed ID: 15025515
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  • 12. Cyclic conversion of the novel Src kinase inhibitor [7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine (TG100435) and Its N-oxide metabolite by flavin-containing monoxygenases and cytochrome P450 reductase.
    Kousba A, Soll R, Yee S, Martin M.
    Drug Metab Dispos; 2007 Dec 15; 35(12):2242-51. PubMed ID: 17881660
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  • 13. S-(1,2,2-trichlorovinyl)-L-cysteine sulfoxide, a reactive metabolite of S-(1,2,2-Trichlorovinyl)-L-cysteine formed in rat liver and kidney microsomes, is a potent nephrotoxicant.
    Elfarra AA, Krause RJ.
    J Pharmacol Exp Ther; 2007 Jun 15; 321(3):1095-101. PubMed ID: 17347324
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  • 17. Stereoselective sulfoxidation of sulindac sulfide by flavin-containing monooxygenases. Comparison of human liver and kidney microsomes and mammalian enzymes.
    Hamman MA, Haehner-Daniels BD, Wrighton SA, Rettie AE, Hall SD.
    Biochem Pharmacol; 2000 Jul 01; 60(1):7-17. PubMed ID: 10807940
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  • 18. Methionine S-oxidation in human and rabbit liver microsomes: evidence for a high-affinity methionine S-oxidase activity that is distinct from flavin-containing monooxygenase 3.
    Ripp SL, Itagaki K, Philpot RM, Elfarra AA.
    Arch Biochem Biophys; 1999 Jul 15; 367(2):322-32. PubMed ID: 10395751
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  • 19. In vitro metabolism of clindamycin in human liver and intestinal microsomes.
    Wynalda MA, Hutzler JM, Koets MD, Podoll T, Wienkers LC.
    Drug Metab Dispos; 2003 Jul 15; 31(7):878-87. PubMed ID: 12814964
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  • 20. Comparative cytotoxicity of 14 novel selenocysteine se-conjugates in rat renal proximal tubular cells.
    Andreadou I, van de Water B, Commandeur JN, Nagelkerke FJ, Vermeulen NP.
    Toxicol Appl Pharmacol; 1996 Nov 15; 141(1):278-87. PubMed ID: 8917701
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