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148 related items for PubMed ID: 11170867

  • 1. Interactions between adenovirus proteins and the p53 pathway: the development of ONYX-015.
    McCormick F.
    Semin Cancer Biol; 2000 Dec; 10(6):453-9. PubMed ID: 11170867
    [Abstract] [Full Text] [Related]

  • 2. ONYX-015 selectivity and the p14ARF pathway.
    McCormick F.
    Oncogene; 2000 Dec 27; 19(56):6670-2. PubMed ID: 11426653
    [Abstract] [Full Text] [Related]

  • 3. Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein.
    Shen Y, Kitzes G, Nye JA, Fattaey A, Hermiston T.
    J Virol; 2001 May 27; 75(9):4297-307. PubMed ID: 11287579
    [Abstract] [Full Text] [Related]

  • 4. Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?
    Dix BR, Edwards SJ, Braithwaite AW.
    J Virol; 2001 Jun 27; 75(12):5443-7. PubMed ID: 11356950
    [No Abstract] [Full Text] [Related]

  • 5. Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts.
    Geoerger B, Grill J, Opolon P, Morizet J, Aubert G, Terrier-Lacombe MJ, Bressac De-Paillerets B, Barrois M, Feunteun J, Kirn DH, Vassal G.
    Cancer Res; 2002 Feb 01; 62(3):764-72. PubMed ID: 11830531
    [Abstract] [Full Text] [Related]

  • 6. Efficacy of a replication-selective adenovirus against ovarian carcinomatosis is dependent on tumor burden, viral replication and p53 status.
    Heise C, Ganly I, Kim YT, Sampson-Johannes A, Brown R, Kirn D.
    Gene Ther; 2000 Nov 01; 7(22):1925-9. PubMed ID: 11127580
    [Abstract] [Full Text] [Related]

  • 7. Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).
    Ries SJ, Brandts CH, Chung AS, Biederer CH, Hann BC, Lipner EM, McCormick F, Korn WM.
    Nat Med; 2000 Oct 01; 6(10):1128-33. PubMed ID: 11017144
    [Abstract] [Full Text] [Related]

  • 8. p53 selective and nonselective replication of an E1B-deleted adenovirus in hepatocellular carcinoma.
    Vollmer CM, Ribas A, Butterfield LH, Dissette VB, Andrews KJ, Eilber FC, Montejo LD, Chen AY, Hu B, Glaspy JA, McBride WH, Economou JS.
    Cancer Res; 1999 Sep 01; 59(17):4369-74. PubMed ID: 10485485
    [Abstract] [Full Text] [Related]

  • 9. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity.
    O'Shea CC, Johnson L, Bagus B, Choi S, Nicholas C, Shen A, Boyle L, Pandey K, Soria C, Kunich J, Shen Y, Habets G, Ginzinger D, McCormick F.
    Cancer Cell; 2004 Dec 01; 6(6):611-23. PubMed ID: 15607965
    [Abstract] [Full Text] [Related]

  • 10. p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication.
    Harada JN, Berk AJ.
    J Virol; 1999 Jul 01; 73(7):5333-44. PubMed ID: 10364280
    [Abstract] [Full Text] [Related]

  • 11. E1B 55K sequesters WT1 along with p53 within a cytoplasmic body in adenovirus-transformed kidney cells.
    Maheswaran S, Englert C, Lee SB, Ezzel RM, Settleman J, Haber DA.
    Oncogene; 1998 Apr 23; 16(16):2041-50. PubMed ID: 9572485
    [Abstract] [Full Text] [Related]

  • 12. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial.
    Nemunaitis J, Ganly I, Khuri F, Arseneau J, Kuhn J, McCarty T, Landers S, Maples P, Romel L, Randlev B, Reid T, Kaye S, Kirn D.
    Cancer Res; 2000 Nov 15; 60(22):6359-66. PubMed ID: 11103798
    [Abstract] [Full Text] [Related]

  • 13. A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer.
    Ganly I, Kirn D, Eckhardt G, Rodriguez GI, Soutar DS, Otto R, Robertson AG, Park O, Gulley ML, Heise C, Von Hoff DD, Kaye SB.
    Clin Cancer Res; 2000 Mar 15; 6(3):798-806. PubMed ID: 10741699
    [Abstract] [Full Text] [Related]

  • 14. Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial.
    Mulvihill S, Warren R, Venook A, Adler A, Randlev B, Heise C, Kirn D.
    Gene Ther; 2001 Feb 15; 8(4):308-15. PubMed ID: 11313805
    [Abstract] [Full Text] [Related]

  • 15. Efficient induction of cell death by adenoviruses requires binding of E1B55k and p53.
    Dix BR, O'Carroll SJ, Myers CJ, Edwards SJ, Braithwaite AW.
    Cancer Res; 2000 May 15; 60(10):2666-72. PubMed ID: 10825139
    [Abstract] [Full Text] [Related]

  • 16. In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy.
    Rogulski KR, Freytag SO, Zhang K, Gilbert JD, Paielli DL, Kim JH, Heise CC, Kirn DH.
    Cancer Res; 2000 Mar 01; 60(5):1193-6. PubMed ID: 10728673
    [Abstract] [Full Text] [Related]

  • 17. Replication and cytolysis of an E1B-attenuated adenovirus in drug-resistant ovarian tumour cells is associated with reduced apoptosis.
    Ganly I, Kim YT, Hann B, Balmain A, Brown R.
    Gene Ther; 2001 Mar 01; 8(5):369-75. PubMed ID: 11313813
    [Abstract] [Full Text] [Related]

  • 18. p53/E1b58kDa complex regulates adenovirus replication.
    Ridgway PJ, Hall AR, Myers CJ, Braithwaite AW.
    Virology; 1997 Oct 27; 237(2):404-13. PubMed ID: 9356351
    [Abstract] [Full Text] [Related]

  • 19. Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus.
    Liu TC, Wang Y, Hallden G, Brooks G, Francis J, Lemoine NR, Kirn D.
    Gene Ther; 2005 Sep 27; 12(17):1333-46. PubMed ID: 15920462
    [Abstract] [Full Text] [Related]

  • 20. Coexpression of the adenovirus 12 E1B 55 kDa oncoprotein and cellular tumor suppressor p53 is sufficient to induce metaphase fragility of the human RNU2 locus.
    Liao D, Yu A, Weiner AM.
    Virology; 1999 Feb 01; 254(1):11-23. PubMed ID: 9927570
    [Abstract] [Full Text] [Related]

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