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Journal Abstract Search

121 related items for PubMed ID: 11172732

  • 1. Structure-activity investigation of the inhibition of 3-hydroxypyridin-4-ones on mammalian tyrosine hydroxylase.
    Liu ZD, Lockwood M, Rose S, Theobald AE, Hider RC.
    Biochem Pharmacol; 2001 Feb 01; 61(3):285-90. PubMed ID: 11172732
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure-activity investigation of metalloenzyme inhibition by iron chelators.
    Liu ZD, Kayyali R, Hider RC, Porter JB, Theobald AE.
    J Med Chem; 2002 Jan 31; 45(3):631-9. PubMed ID: 11806714
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, physicochemical characterization, and biological evaluation of 2-(1'-hydroxyalkyl)-3-hydroxypyridin-4-ones: novel iron chelators with enhanced pFe(3+) values.
    Liu ZD, Khodr HH, Liu DY, Lu SL, Hider RC.
    J Med Chem; 1999 Nov 18; 42(23):4814-23. PubMed ID: 10579844
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of catechol-O-methyltransferase (COMT) as well as tyrosine and tryptophan hydroxylase by the orally active iron chelator, 1,2-dimethyl-3-hydroxypyridin-4-one (L1, CP20), in rat brain in vivo.
    Waldmeier PC, Buchle AM, Steulet AF.
    Biochem Pharmacol; 1993 Jun 22; 45(12):2417-24. PubMed ID: 7687131
    [Abstract] [Full Text] [Related]

  • 5. Structure-function investigation of the interaction of 1- and 2-substituted 3-hydroxypyridin-4-ones with 5-lipoxygenase and ribonucleotide reductase.
    Kayyali R, Porter JB, Liu ZD, Davies NA, Nugent JH, Cooper CE, Hider RC.
    J Biol Chem; 2001 Dec 28; 276(52):48814-22. PubMed ID: 11602611
    [Abstract] [Full Text] [Related]

  • 6. Hexadentate 3-hydroxypyridin-4-ones with high iron(III) affinity: design, synthesis and inhibition on methicillin resistant Staphylococcus aureus and Pseudomonas strains.
    Zhou YJ, Liu MS, Osamah AR, Kong XL, Alsam S, Battah S, Xie YY, Hider RC, Zhou T.
    Eur J Med Chem; 2015 Apr 13; 94():8-21. PubMed ID: 25747496
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and physicochemical assessment of novel 2-substituted 3-hydroxypyridin-4-ones, novel iron chelators.
    Moridani MY, Tilbrook GS, Khodr HH, Hider RC.
    J Pharm Pharmacol; 2002 Mar 13; 54(3):349-64. PubMed ID: 11902801
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and evaluation of N-basic substituted 3-hydroxypyridin-4-ones: orally active iron chelators with lysosomotrophic potential.
    Liu ZD, Khodr HH, Lu SL, Hider RC.
    J Pharm Pharmacol; 2000 Mar 13; 52(3):263-72. PubMed ID: 10757413
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of 2-amido-3-hydroxypyridin-4(1H)-ones: novel iron chelators with enhanced pFe3+ values.
    Liu ZD, Piyamongkol S, Liu DY, Khodr HH, Lu SL, Hider RC.
    Bioorg Med Chem; 2001 Mar 13; 9(3):563-73. PubMed ID: 11310590
    [Abstract] [Full Text] [Related]

  • 10. Iron mobilization from hepatocyte monolayer cultures by chelators: the importance of membrane permeability and the iron-binding constant.
    Porter JB, Gyparaki M, Burke LC, Huehns ER, Sarpong P, Saez V, Hider RC.
    Blood; 1988 Nov 13; 72(5):1497-503. PubMed ID: 3179437
    [Abstract] [Full Text] [Related]

  • 11. Basic 3-hydroxypyridin-4-ones: potential antimalarial agents.
    Dehkordi LS, Liu ZD, Hider RC.
    Eur J Med Chem; 2008 May 13; 43(5):1035-47. PubMed ID: 17869385
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and in-vitro antimicrobial evaluation of a high-affinity iron chelator in combination with chloramphenicol.
    Zhu CF, Qiu DH, Kong XL, Hider RC, Zhou T.
    J Pharm Pharmacol; 2013 Apr 13; 65(4):512-20. PubMed ID: 23488779
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, physicochemical properties, and evaluation of N-substituted-2-alkyl-3-hydroxy-4(1H)-pyridinones.
    Rai BL, Dekhordi LS, Khodr H, Jin Y, Liu Z, Hider RC.
    J Med Chem; 1998 Aug 27; 41(18):3347-59. PubMed ID: 9719587
    [Abstract] [Full Text] [Related]

  • 14. Design and synthesis of fluorinated iron chelators for metabolic study and brain uptake.
    Ma Y, Roy S, Kong X, Chen Y, Liu D, Hider RC.
    J Med Chem; 2012 Mar 08; 55(5):2185-95. PubMed ID: 22339047
    [Abstract] [Full Text] [Related]

  • 15. Identification of the di-pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti-tumour agents.
    Becker EM, Lovejoy DB, Greer JM, Watts R, Richardson DR.
    Br J Pharmacol; 2003 Mar 08; 138(5):819-30. PubMed ID: 12642383
    [Abstract] [Full Text] [Related]

  • 16. Iron mobilization from myocardial cells by 3-hydroxypyridin-4-one chelators: studies in rat heart cells in culture.
    Hershko C, Link G, Pinson A, Peter HH, Dobbin P, Hider RC.
    Blood; 1991 May 01; 77(9):2049-53. PubMed ID: 2018841
    [Abstract] [Full Text] [Related]

  • 17. Hydrolyzable Tannins Are Iron Chelators That Inhibit DNA Repair Enzyme ALKBH2.
    Chen F, Tang Q, Ma H, Bian K, Seeram NP, Li D.
    Chem Res Toxicol; 2019 Jun 17; 32(6):1082-1086. PubMed ID: 31088072
    [Abstract] [Full Text] [Related]

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  • 19. Hydrolytic and metabolic characteristics of the esters of 1-(3'-hydroxypropyl)-2-methyl-3-hydroxypyridin-4-one (CP41), potentially useful iron chelators.
    Liu DY, Liu ZD, Lu SL, Hider RC.
    Pharmacol Toxicol; 2000 May 17; 86(5):228-33. PubMed ID: 10862505
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, physical-chemical characterisation and biological evaluation of novel 2-amido-3-hydroxypyridin-4(1H)-ones: Iron chelators with the potential for treating Alzheimer's disease.
    Gaeta A, Molina-Holgado F, Kong XL, Salvage S, Fakih S, Francis PT, Williams RJ, Hider RC.
    Bioorg Med Chem; 2011 Feb 01; 19(3):1285-97. PubMed ID: 21236688
    [Abstract] [Full Text] [Related]

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